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Basic Information
CAS No.: 527-62-8
Name: 2-AMINO-4,6-DICHLOROPHENOL
Article Data: 23
Molecular Structure:
Molecular Structure of 527-62-8 (2-AMINO-4,6-DICHLOROPHENOL)
Formula: C6H5 Cl2 N O
Molecular Weight: 178.018
Synonyms: 2,4-Dichloro-6-aminophenol;2-Amino-4,6-dichlorophenol; 4,6-Dichloro-2-aminophenol;4,6-Dichloro-o-aminophenol; 6-Amino-2,4-dichlorophenol; NSC 658464
EINECS: 208-421-3
Density: 1.56 g/cm3
Melting Point: 97 ºC
Boiling Point: 286.5 °C at 760 mmHg
Flash Point: 127.1 °C
Appearance: light yellow or white solid
Safety: Mutation data reported. When heated to decomposition it emits toxic vapors of NOx and Cl.
PSA: 46.25000
LogP: 2.86240
Synthetic route
609-89-2

2,4-dichloro-6-nitrophenol

527-62-8

2,4-dichloro-6-aminophenol

Conditions
ConditionsYield
With hydrogen; platinum(IV) oxide In ethanol at 20℃; under 750.06 Torr; for 96h;99%
With tin(ll) chloride In ethanol97%
With sodium dithionite In ethanol; water at 65℃; for 4h;60%
609-89-2

2,4-dichloro-6-nitrophenol

7772-99-8

stannous chloride

527-62-8

2,4-dichloro-6-aminophenol

Conditions
ConditionsYield
In ethanol80%
In ethanol80%
In ethanol80%
139137-46-5

trans-2,4-dichloro-6-phenylazo-phenol

527-62-8

2,4-dichloro-6-aminophenol

Conditions
ConditionsYield
With sodium dithionite
7647-01-0

hydrogenchloride

858013-68-0

4,6,4',6'-tetrachloro-2,2'-azo-di-phenol

tin (II)-chloride

tin (II)-chloride

527-62-8

2,4-dichloro-6-aminophenol

2,4-dichloro-6-isopropylideneamino-phenol

527-62-8

2,4-dichloro-6-aminophenol

Conditions
ConditionsYield
With hydrogenchloride In benzene

propan-2-one O-(2,4-dichloro-phenyl)-oxime

527-62-8

2,4-dichloro-6-aminophenol

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: ZrCl4 / benzene / 0.2 h / reflux
2: 10 percent HCl / benzene
View Scheme
120-83-2

2,4-dichlorophenol

527-62-8

2,4-dichloro-6-aminophenol

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: fuming nitric acid
2: tin; hydrochloric acid
View Scheme
108-95-2

phenol

527-62-8

2,4-dichloro-6-aminophenol

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: chlorine
2: fuming nitric acid
3: tin; hydrochloric acid
View Scheme

sodium dithionate

609-89-2

2,4-dichloro-6-nitrophenol

527-62-8

2,4-dichloro-6-aminophenol

Conditions
ConditionsYield
In water; sodium hydrogencarbonate
527-62-8

2,4-dichloro-6-aminophenol

219963-60-7

4-methoxy-3-(4-(2,2,2-trichloro-acetyl)piperazin-1-yl)benzene-1-sulfonylchloride

1331830-34-2

N-(3,5-dichloro-2-hydroxyphenyl)-4-methoxy-3-[4-(2,2,2-trichloroethanoyl)-piperazin-1-yl]-benzenesulfonamide

Conditions
ConditionsYield
With pyridine In dichloromethane at 0 - 20℃; Inert atmosphere;96%
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Chemistry

Empirical Formula: C6H5Cl2NO
Molecular Weight: 178.016 
EINECS: 208-421-3
Index of Refraction: 1.661 Molar
Density: 1.56 g/cm3
Flash Point: 127.1 °C
Enthalpy of Vaporization: 54.67 kJ/mol
Boiling Point: 286.5 °C at 760 mmHg
Vapour Pressure: 0.00153 mmHg at 25 °C 
Melting point: 97 °C
Appearance: Long needles
Product categories of 2-Amino-4,6-dichlorophenol (CAS.527-62-8): Aromatic Phenols
Structure of 2-Amino-4,6-dichlorophenol (CAS.527-62-8):

Toxicity Data With Reference

1.    

mnt-ham-lng 200 mg/L

    MUREAV    Mutation Research. 368 (1996),149.
2.    

sce-ham-lng 100 mg/L

    MUREAV    Mutation Research. 368 (1996),149.

Safety Profile

Mutation data reported. When heated to decomposition it emits toxic vapors of NOx and Cl.
 

Hazard Note: Irritant

Specification

 2-Amino-4,6-dichlorophenol (CAS.527-62-8) also can be called 2,4-Dichloro-6-aminophenol and; Phenol, 2-amino-4,6-dichloro- . It is probably combustible, and may react with strong oxidizers and mineral acids or bases .