Reference

Cinnamic acid-containing sun protectant for human skin

Cinnamic acid-containing sun protectant for human skin.Some chemicals with cas registry numbers like 36861-47-9 and 103-36-6 are also used. Moeller, Hinrich; Thimm, Hans J. (Henkel und Cie. G.m.b.H., Ger.). Ger. Offen. DE 2529511 20 Jan 1977, 11 pp. (German). (Germany). CODEN: GWXXBX. CLASS: IC: A61K007-42. APPLICATION: DE 75-2529511 2 Jul 1975. DOCUMENT TYPE: Patent CA Section: 63 (Pharmaceuticals) Section cross-reference(s): 1 Antiinflammatory sun-protective compns. for human skin contain 1-10% of a UV light-filtering substance and 1-10% of a cinnamic acid ester (PhCH:CHCO2R, R = C1-6 alkyl). For example, 40g Et cinnamate (I) [103-36-6] and 40 g 2-ethylhexyl p-methoxycinnamate [5466-77-3] were suspended in 100 g paraffin oil by warming, and 300 g lecithin-contg. vegetable oil, 400 g olive oil, 100 g iso-Pr myristate, and 100 g purcillin oil were mixed with the suspension to give a sun-protecting oil. I and Me cinnamate [103-26-4] administered orally to rats inhibited dextran edema by 37 and 35%, resp., UV edema in hairless mice by 71 and 68%, resp., after 63 h. UV erythema was inhibited 55 and 54% by 5% tinctures of these compds., resp. .

Sunscreen

Sunscreen. Mutzhas, Maximilian Friedrich P. (Fed. Rep. Ger. ). Ger. Offen. DE 3238514 A1 19 Apr 1984,24 pp. (German). (Germany). CODEN: GWXXBX. CLASS: IC: A61K007-42; A61K007-44. APPLICATION: DE 82-3238514 18 Oct 1982. DOCUMENT TYPE: Patent CA Section: 62 (Essential Oils and Cosmetics) Sunscreens contain an oil-sol. UV absorber in a hydrophobic oil and a H2O-sol. UV absorber in an alc. and 310% of an aq. component contg. a polyhydric or monohydric alc. The sunscreens provide high sun protection factors without feeling sticky on the skin. The components are packaged in a container that allows mixing before application to the skin. A prepn. that had a refreshing feel on the skin contained equal parts by wt. of a soln. of 3,3,5-trimethylcyclohexyl salicylate [118-56-9] 10, isoamyl p-methoxycinnamate [71617-10-2] 10, ethylhexyl p-methoxycinnamate [5466-77-3] 10, 2-ethylhexyl p-dimethylaminobenzoate [21245-02-3] 8, in iso-PrOH 12% and a soln. of ethoxylated p-methoxybenzoate ester 10, 2-hydroxy-4-methoxybenzophenone-5-sulfonic acid [4065-45-6] 5, iso-PrOH 15, and H2O 20%.