Reference

The INOC approach to the hydroazulenone ring system - a potential entry to the guaianolides and pseudoguaianolides

The INOC approach to the hydroazulenone ring system - a potential entry to the guaianolides and pseudoguaianolides. Kozikowski, Alan P.; Mugrage, Benjamin B.; Wang, B. C.; Xu, Zhangbao (Dep. Chem., Univ. Pittsburgh, Pittsburgh, PA 15260, USA). Tetrahedron Lett., 24(35), 3705-8 (English) 1983. CODEN: TELEAY. ISSN: 0040-4039. DOCUMENT TYPE: Journal CA Section: 30 (Terpenes and Terpenoids) Boiling malonate I in benzene contg. Et3N with the addn.In this experiment, several chemicals are used like 88444-67-1 and 6940-78-9 of PhNCO gave 83% isoxazoloazulene II, a potential synthon for guaianolides and pseudoguaianolides. .

Two-step preparation of C3-8 a,w-bromochloroalkanes from C3-8 cyclic ethers

Two-step preparation of C3-8 a,w-bromochloroalkanes from C3-8 cyclic ethers. Drivon, Gilles; Ruppin, Christophe (Elf Atochem Sa, Fr.). Fr. Demande FR 2736635 A1 17 Jan 1997, 9 pp. (French). (France). CODEN: FRXXBL. CLASS: ICM: C07C017-16. APPLICATION: FR 1995-8361 11 Jul 1995. 6940-78-9 and 10035-10-6 are cas registry numbers of chemicals which are used as reagents here. DOCUMENT TYPE: Patent CA Section: 23 (Aliphatic Compounds) Section cross-reference(s): 45 a,w-Bromochloroalkanes Br(CH2)nCl (n = 3-8), useful as chem. intermediates, are prepd. by the ring-opening hydrobrominolysis of the corresponding C3-8 cyclic ethers with HBr, followed by dehydrative chlorination of the unisolated bromoalkanols with SOCl2 in a carboxamide solvent. Thus, THF was reacted with HBr, then DMF and SOCl2 added to the first reaction mixt., producing 1-bromo-4-chlorobutane in 83% yield. .