- (R)-((2-(Bromomethyl)-3-methylbutoxy)methyl)benzene
- (R)-(-)-1-Indanol
- (R)-(-)-1-Indanyl isothiocyanate
- (R)-(-)-2-(2,5-Dihydrophenyl)glycine
- (R)-(-)-2-Amino-1-butanol
- (R)-(-)-2-Amino-1-propanol
- (R)-(-)-2-Benzylamino-1-phenylethanol
- (R)-(-)-2-Methylpiperazine
- (R)-(-)-2-phenylpropionic acid
- (R)-(-)-2-Propyloctanoic acid
- 18621-17-51-(Diphenylmethyl)-3-hydroxyazetidine
- 18621-18-63-Hydroxyazetidine hydrochloride
- 1862-17-54-Morpholinehexanoicacid, e-oxo-
- 18622-23-6[1,1'-Biphenyl]-4-carboxylicacid, hydrazide
- 18622-28-1Cyanamide, N-cyano-, zinc salt (2:1)
- 18623-11-5Silane, octadecyl-
- 18623-13-71,9-Dioxa-2,8,10,16-tetrasilacyclohexadecane-5,13-dione,2,2,8,8,10,10,16,16-octamethyl-
- 18625-12-2Butanoic acid,4-(2,4-dichlorophenoxy)-, methyl ester
- 18625-22-4Glycine,D-leucylglycyl-
- 186259-63-29H-Fluorene,2,7-dibromo-9,9-diphenyl-
Hot Products
- 104987-11-3Tacrolimus
- 141-53-7Sodium formate
- 8001-54-5Quaternary ammonium compounds, alkylbenzyldimethyl, chlorides
- 9003-39-8Povidone
- 10161-34-9Trenbolone acetate
- 402957-28-2Telaprevir
- 68-19-9Cyanocobalamin
- 7631-86-9Silicon dioxide
- 302-79-4Tretinoin
- 77-92-9Citric acid
|
Basic Information |
|
Post buying leads |
|
Suppliers |
|
Cas Database |
| Name |
(R,R)-1,2-Bis(methanesulfonyloxymethyl)cyclohexane |
EINECS | 1308068-626-2 |
| CAS No. | 186204-35-3 | Density | 1.271 g/cm3 |
| PSA | 103.50000 | LogP | 2.90680 |
| Solubility | N/A | Melting Point |
N/A |
| Formula | C10H20O6S2 | Boiling Point | 495.284 °C at 760 mmHg |
| Molecular Weight | 300.397 | Flash Point | 253.339 °C |
| Transport Information | N/A | Appearance | off-white solid |
| Safety | Risk Codes | N/A | |
| Molecular Structure |
|
Hazard Symbols | N/A |
| Synonyms |
(1R,2R)-1,2-Cyclohexanediylbis(methylene) dimethanesulfonate; |
Article Data | 10 |
(R,R)-1,2-Bis(methanesulfonyloxymethyl)cyclohexane Synthetic route
- 65376-05-8
(+)-(1R,2R)-trans-1,2-bis(hydroxymethyl)cyclohexane
- 124-63-0
methanesulfonyl chloride
- 186204-35-3
(1R,2R)-(-)-trans-cyclohexane-1,2-diylbis(methylene)dimethanesulfonate
| Conditions | Yield |
|---|---|
| With triethylamine at 0 - 5℃; Industrial scale; | 92.6% |
| With triethylamine In dichloromethane at 0 - 20℃; Inert atmosphere; | 92% |
| With triethylamine In chloroform at 0 - 20℃; for 5h; | 90.8% |
- 131-11-3
phthalic acid dimethyl ester
- 186204-35-3
(1R,2R)-(-)-trans-cyclohexane-1,2-diylbis(methylene)dimethanesulfonate
| Conditions | Yield |
|---|---|
| Multi-step reaction with 4 steps 1: Raney nickel; methanol / 50 - 60 °C / 73550.8 Torr / Hydrogenation.Behandeln des Reaktionsprodukts mit methanol. Natriummethylat 2: LiAlH4; diethyl ether 3: (1R)-menthyl isocyanate 4: pyridine View Scheme |
- 76155-27-6
(+/-)-trans-2-(hydroxymethyl)cyclohexylmethanol
- 186204-35-3
(1R,2R)-(-)-trans-cyclohexane-1,2-diylbis(methylene)dimethanesulfonate
| Conditions | Yield |
|---|---|
| Multi-step reaction with 2 steps 1: (1R)-menthyl isocyanate 2: pyridine View Scheme |
- 3205-35-4
dimethyl cyclohexane-trans-1,2-dicarboxylate
- 186204-35-3
(1R,2R)-(-)-trans-cyclohexane-1,2-diylbis(methylene)dimethanesulfonate
| Conditions | Yield |
|---|---|
| Multi-step reaction with 3 steps 1: LiAlH4; diethyl ether 2: (1R)-menthyl isocyanate 3: pyridine View Scheme |
- 46022-05-3
(1R,2R)-(-)-trans-cyclohexane-1,2-dicarboxylic acid
- 186204-35-3
(1R,2R)-(-)-trans-cyclohexane-1,2-diylbis(methylene)dimethanesulfonate
| Conditions | Yield |
|---|---|
| Multi-step reaction with 3 steps 1.1: sulfuric acid / 18 h / 40 °C 2.1: diisobutylaluminium hydride / toluene / 6 h / -5 - 20 °C / Inert atmosphere 2.2: 13 h / -5 - 40 °C 3.1: triethylamine / chloroform / 5 h / 0 - 20 °C View Scheme | |
| Multi-step reaction with 2 steps 1.1: lithium aluminium tetrahydride / tetrahydrofuran / 3 h / 65 °C 2.1: triethylamine / dichloromethane / 0.42 h / 25 - 35 °C / Inert atmosphere 2.2: 3 h / -5 - 35 °C View Scheme | |
| Multi-step reaction with 4 steps 1: tetrahydrofuran / 1 h / 25 - 30 °C 2: tetrahydrofuran / 45 - 50 °C 3: sodium tetrahydroborate; water / tetrahydrofuran / 1 h 4: triethylamine / dichloromethane View Scheme | |
| Multi-step reaction with 3 steps 1: sulfuric acid / 4 h / Reflux 2: sodium tetrahydroborate; methanol / tetrahydrofuran / 3 h / 40 °C / Reflux 3: triethylamine / dichloromethane / 1.5 h / 20 °C View Scheme |
- 140459-96-7
(1R,2R)-1,2-cyclohexanedicarboxylic acid dimethyl ester
- 186204-35-3
(1R,2R)-(-)-trans-cyclohexane-1,2-diylbis(methylene)dimethanesulfonate
| Conditions | Yield |
|---|---|
| Multi-step reaction with 2 steps 1.1: diisobutylaluminium hydride / toluene / 6 h / -5 - 20 °C / Inert atmosphere 1.2: 13 h / -5 - 40 °C 2.1: triethylamine / chloroform / 5 h / 0 - 20 °C View Scheme | |
| Multi-step reaction with 2 steps 1: sodium tetrahydroborate; methanol / tetrahydrofuran / 3 h / 40 °C / Reflux 2: triethylamine / dichloromethane / 1.5 h / 20 °C View Scheme |
- 186204-35-3
(1R,2R)-(-)-trans-cyclohexane-1,2-diylbis(methylene)dimethanesulfonate
- 14805-29-9
(3aR,4S,7R,7aS)‑4,7‑methylene‑1H‑isoindole‑1,3(2H)-dione
| Conditions | Yield |
|---|---|
| With potassium carbonate In isopropyl alcohol for 4h; | 99% |
- 186204-35-3
(1R,2R)-(-)-trans-cyclohexane-1,2-diylbis(methylene)dimethanesulfonate
- 111-42-2
2,2'-iminobis[ethanol]
- 1421374-96-0
(3aR,7aR)-2,2-bis(2-hydroxyethyl)octahydro-1H-isoindolium mesylate
| Conditions | Yield |
|---|---|
| With sodium carbonate In chlorobenzene Reflux; | 99% |
- 186204-35-3
(1R,2R)-(-)-trans-cyclohexane-1,2-diylbis(methylene)dimethanesulfonate
- 87691-87-0
3-(1-piperazinyl)-1,2-benzisothiazole
- 186204-37-5
(3aR,7aR)-4’-(benzo[d]isothiazol-3-yl)octahydrospiro[isoindole-2,1’-piperazin]-2-ium methanesulfonate
| Conditions | Yield |
|---|---|
| With calcium hydroxide In isopropyl alcohol for 20h; Reflux; Industrial scale; | 97.3% |
| With potassium carbonate In water; acetonitrile at 82℃; for 3h; Temperature; Concentration; Solvent; | 91% |
| With sodium carbonate In acetonitrile at 80 - 85℃; for 24h; | 89.5% |
- 186204-35-3
(1R,2R)-(-)-trans-cyclohexane-1,2-diylbis(methylene)dimethanesulfonate
- 186204-37-5
(3aR,7aR)-4’-(benzo[d]isothiazol-3-yl)octahydrospiro[isoindole-2,1’-piperazin]-2-ium methanesulfonate
| Conditions | Yield |
|---|---|
| With potassium carbonate In acetonitrile at 80℃; Temperature; | 92.4% |
(R,R)-1,2-Bis(methanesulfonyloxymethyl)cyclohexane Specification
The (R,R)-1,2-Bis(methanesulfonyloxymethyl)cyclohexane, with the CAS registry number 186204-35-3, is also known as (1R-trans)-1,2-Cyclohexanedimethanol dimethanesulfonate. It belongs to the product category of Sulfur & Selenium Compounds. This chemical's molecular formula is C10H20O6S2 and molecular weight is 300.39. What's more, its systematic name is called (1R,2R)-1,2-Cyclohexanediylbis(methylene) dimethanesulfonate.
Physical properties about (R,R)-1,2-Bis(methanesulfonyloxymethyl)cyclohexane are: (1)ACD/LogP: 0.79; (2)# of Rule of 5 Violations: 0; (3)ACD/LogD (pH 5.5): 0.79; (4)ACD/LogD (pH 7.4): 0.79; (5)ACD/BCF (pH 5.5): 2.35; (6)ACD/BCF (pH 7.4): 2.35; (7)ACD/KOC (pH 5.5): 64.11; (8)ACD/KOC (pH 7.4): 64.11; (9)#H bond acceptors: 6; (10)#H bond donors: 0; (11)#Freely Rotating Bonds: 6; (12)Polar Surface Area: 103.5 Å2; (13)Index of Refraction: 1.482; (14)Molar Refractivity: 67.38 cm3; (15)Molar Volume: 236.387 cm3; (16)Surface Tension: 45.57 dyne/cm; (17)Density: 1.271 g/cm3; (18)Flash Point: 253.339 °C; (19)Enthalpy of Vaporization: 73.385 kJ/mol; (20)Boiling Point: 495.284 °C at 760 mmHg; (21)Vapour Pressure: 0 mmHg at 25 °C.
You can still convert the following datas into molecular structure:
(1) SMILES: O=S(=O)(OC[C@@H]1CCCC[C@H]1COS(=O)(=O)C)C
(2) InChI: InChI=1S/C10H20O6S2/c1-17(11,12)15-7-9-5-3-4-6-10(9)8-16-18(2,13)14/h9-10H,3-8H2,1-2H3/t9-,10-/m0/s1
(3) InChIKey: JIHKCHWEXXZTOU-UWVGGRQHSA-N
What can I do for you?
Get Best Price
