- 1-(p-CHLOROPHENYL)-5-ISOPROPYLBI GUANIDE HYDROCHLORIDE
- 1-(p-Chlorophenyl)-5-isopropylbiguanide
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| Name |
1-(p-CHLOROPHENYL)-5-ISOPROPYLBI GUANIDE HYDROCHLORIDE |
EINECS | N/A |
| CAS No. | 637-32-1 | Density | N/A |
| PSA | 83.79000 | LogP | 4.06530 |
| Solubility | N/A | Melting Point |
249-2510C |
| Formula | C11H16 Cl N5 . Cl H | Boiling Point | 402.7oC at 760 mmHg |
| Molecular Weight | 290.195 | Flash Point | 197.4oC |
| Transport Information | N/A | Appearance | N/A |
| Safety | Poison by ingestion and intravenous routes. Experimental reproductive effects. An antimalarial drug. When heated to decomposition it emits very toxic fumes of Cl− and NOx. | Risk Codes | 25 |
| Molecular Structure |
|
Hazard Symbols | T |
| Synonyms |
Biguanide,1-(p-chlorophenyl)-5-isopropyl-, monohydrochloride (8CI); Imidodicarbonimidicdiamide, N-(4-chlorophenyl)-N'-(1-methylethyl)-, monohydrochloride (9CI);1-(p-Chlorophenyl)-5-isopropylbiguanide hydrochloride; 3359 RP; Chloroguanidehydrochloride; Chloroquanil; Diguanyl; Drinupal; Drinupal hydrochloride; Guanatol;Guanatol hydrochloride; M 4888; Paludrine; Paludrine hydrochloride; Palusil;Palusil hydrochloride; Proguanil hydrochloride; RP 3359; SN 12,837; SN 12837;Tirian; Tirian hydrochloride |
1-(p-CHLOROPHENYL)-5-ISOPROPYLBI GUANIDE HYDROCHLORIDE Chemical Properties
IUPAC Name: (1E)-1-[Amino-(4-chloroanilino)methylidene]-2-propan-2-ylguanidine hydrochloride
The MF of Proguanil hydrochloride (CAS NO.637-32-1) is C11H17Cl2N5.
The MW of Proguanil hydrochloride (CAS NO.637-32-1) is 290.19.
Synonyms of Proguanil hydrochloride (CAS NO.637-32-1): Biguanide, 1- (p-chlorophenyl)-5-isopropyl-, monohydrochloride ; Palusil (hydrochloride) ; Diguanyl (hydrochloride)
Product Categories: Aromatics;Bases & Related Reagents;Intermediates & Fine Chemicals
Flash Point: 197.4 °C
Boiling Point: 402.7 °C
Melting Point: 249-251 °C
Apperance: White Solid
EINECS: 211-283-7
1-(p-CHLOROPHENYL)-5-ISOPROPYLBI GUANIDE HYDROCHLORIDE Uses
Proguanil hydrochloride (CAS NO.637-32-1) is used as antimalarial.
1-(p-CHLOROPHENYL)-5-ISOPROPYLBI GUANIDE HYDROCHLORIDE Toxicity Data With Reference
| 1. | orl-rat LD50:58 mg/kg | JPETAB Journal of Pharmacology and Experimental Therapeutics. 91 (1947),157. | ||
| 2. | ivn-rat LD50:33 mg/kg | JPETAB Journal of Pharmacology and Experimental Therapeutics. 91 (1947),157. | ||
| 3. | orl-mus LD50:27 mg/kg | JPETAB Journal of Pharmacology and Experimental Therapeutics. 91 (1947),157. | ||
| 4. | ivn-mus LD50:23 mg/kg | JPETAB Journal of Pharmacology and Experimental Therapeutics. 91 (1947),157. | ||
| 5. | orl-rbt LD50:172 mg/kg | BJPCAL British Journal of Pharmacology and Chemotherapy. 2 (1947),181. | ||
| 6. | ivn-rbt LD50:44,850 µg/kg | JPETAB Journal of Pharmacology and Experimental Therapeutics. 91 (1947),157. | ||
| 7. | ivn-gpg LD50:39,510 µg/kg | JPETAB Journal of Pharmacology and Experimental Therapeutics. 91 (1947),157. | ||
| 8. | orl-ckn LD50:400 mg/kg | BJPCAL British Journal of Pharmacology and Chemotherapy. 2 (1947),181. |
1-(p-CHLOROPHENYL)-5-ISOPROPYLBI GUANIDE HYDROCHLORIDE Safety Profile
Poison by ingestion and intravenous routes. Experimental reproductive effects. An antimalarial drug. When heated to decomposition it emits very toxic fumes of Cl− and NOx.Safety information of Proguanil hydrochloride (CAS NO.637-32-1):
RIDADR 3249
HazardClass 6.1(b)
PackingGroup III
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