Welcome to LookChem.com Sign In|Join Free
  • or
Home > Products >  > 

1,2-Diethoxybenzene

Related Products

Hot Products

Name

1,2-Diethoxybenzene

EINECS 218-089-1
CAS No. 2050-46-6 Density 0.975 g/cm3
PSA 18.46000 LogP 2.48400
Solubility 646mg/L at 20℃ Melting Point 43-45 °C
Formula C10H14O2 Boiling Point 218.7 °C at 760 mmHg
Molecular Weight 166.22 Flash Point 73.8 °C
Transport Information N/A Appearance light brown crystalline low melting mass or liquid
Safety 24/25 Risk Codes N/A
Molecular Structure Molecular Structure of 2050-46-6 (1,2-Diethoxybenzene) Hazard Symbols N/A
Synonyms

Benzene,o-diethoxy- (6CI,7CI,8CI);Catechol diethyl ether;NSC6189;o-Diethoxybenzene;

Article Data 21

1,2-Diethoxybenzene Synthetic route

120-80-9

benzene-1,2-diol

75-03-6

ethyl iodide

2050-46-6

1,2-diethoxybenzene

Conditions
ConditionsYield
With potassium carbonate In acetone Heating;88%
With 18-crown-6 ether; potassium carbonate In acetonitrile for 18h; Reflux;76%
With sodium hydroxide
With potassium hydroxide
5409-31-4

3,4-diethoxybenzoic acid

2050-46-6

1,2-diethoxybenzene

Conditions
ConditionsYield
With methyllithium; calcium carbonate bei der Destillation;
64-67-5

diethyl sulfate

120-80-9

benzene-1,2-diol

2050-46-6

1,2-diethoxybenzene

Conditions
ConditionsYield
With potassium carbonate; acetone
94-71-3

2-Ethoxyphenol

75-03-6

ethyl iodide

2050-46-6

1,2-diethoxybenzene

Conditions
ConditionsYield
With potassium hydroxide
With potassium carbonate In DMF (N,N-dimethyl-formamide) at 80℃; for 30h;
120-80-9

benzene-1,2-diol

75-03-6

ethyl iodide

alcoholic potash

alcoholic potash

2050-46-6

1,2-diethoxybenzene

120-80-9

benzene-1,2-diol

haloethane

haloethane

2050-46-6

1,2-diethoxybenzene

Conditions
ConditionsYield
With potassium hydroxide In 2-methoxy-ethanol
120-80-9

benzene-1,2-diol

C2H5Hal

C2H5Hal

2050-46-6

1,2-diethoxybenzene

Conditions
ConditionsYield
With alkali
74-96-4

ethyl bromide

120-80-9

benzene-1,2-diol

2050-46-6

1,2-diethoxybenzene

Conditions
ConditionsYield
With potassium hydroxide In ethanol
75332-44-4

3,4-diethoxybenzoic acid ethyl ester

2050-46-6

1,2-diethoxybenzene

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: diluted NaOH-solution
2: lime/chalk/ / bei der Destillation
View Scheme
120-80-9

benzene-1,2-diol

Et-X (X = Br or I)

Et-X (X = Br or I)

A

94-71-3

2-Ethoxyphenol

B

2050-46-6

1,2-diethoxybenzene

Conditions
ConditionsYield
With potassium carbonate In acetone

1,2-Diethoxybenzene Chemical Properties

Molecular Formula: C10H14O2
Molar mass: 166.22 g/mol
EINECS: 218-089-1
Density: 0.975 g/cm3
Flash Point: 73.8 °C
Melting point: 43-45 °C
Index of Refraction: 1.485
Boiling Point: 218.7 °C at 760 mmHg
Vapour Pressure: 0.183 mmHg at 25°C
Appearance: Light brown crystalline low melting mass or liquid
Product categories: Aromatic ethers
Structure of 1,2-Diethoxybenzene (2050-46-6):
             
XLogP3-AA: 2.4
H-Bond Donor: 0
H-Bond Acceptor: 2
IUPAC Name: 1,2-Diethoxybenzene
Canonical SMILES: CCOC1=CC=CC=C1OCC
InChI: InChI=1S/C10H14O2/c1-3-11-9-7-5-6-8-10(9)12-4-2/h5-8H,3-4H2,1-2H3 
InChIKey: QZYDOKBVZJLQCK-UHFFFAOYSA-N

1,2-Diethoxybenzene Production

Its preparation method is: adding catechol, 25% sodium hydroxide solution, chloroethane and solvent into autoclave, and then heating to 90 ℃ and then keep 5h, and then have de-solvent, filtering to get the product: 1,2-Diethoxybenzene (2050-46-6).Etherification agent can also be replaced with Dimethyl sulfate , O-p-toluenesulfonate ester , Ethyl iodide , Ethyl bromide and so on, but using of chloroethane as etherification agent, it is better fpr raw materials readily available, inexpensive, low cost, high yield characteristics.

1,2-Diethoxybenzene Toxicity Data With Reference

1.    

eye-rbt 100 mg MLD

    FCTOD7    Food and Chemical Toxicology. 20 (1982),573.
2.    

eye-rbt 100 mg/30S RNS MLD

    FCTOD7    Food and Chemical Toxicology. 20 (1982),573.

Carcinogenicity of 1,2-Diethoxybenzene (2050-46-6) hasn't been listed as a carcinogen by NTP, IARC,ACGIH, or CA Prop 65. And its toxicological properties have not been fully investigated.

1,2-Diethoxybenzene Consensus Reports

Reported in EPA TSCA Inventory.

1,2-Diethoxybenzene Safety Profile

An eye irritant. When heated to decomposition it emits acrid smoke and irritating fumes.

1,2-Diethoxybenzene Specification

 1,2-Diethoxybenzene (2050-46-6) also can be called o-Diethoxy benzene ; Benzene, 1,2-diethoxy- ; Benzene, o-diethoxy- ; Catechol diethyl ether .And it is used as raw materials for pharmaceutical and pesticide.
 1,2-Diethoxybenzene (2050-46-6) is hazardous,so the first aid measures and others should be known.Such as: When on the skin: first,should  flush skin with plenty of water immediatelyfor at least 15 minutes while removing contaminated clothing. Secondly,Get shoesmedical aid . Or in the eyes: Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids.Then get medical aid soon.While ,it's Inhaled: Remove from exposure and move to fresh air immediately.Then you have the ingesting of the product : Wash mouth out with water,and get medical aid immediately.
In addition, 1,2-Diethoxybenzene (2050-46-6) is moisture sensitive. It is not compatible with strong oxidizing agents, and you must not take it with incompatible materials.And also prevent it to broken down into hazardous decomposition products: carbon dioxide,carbon monoxide.

Post a RFQ

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

1

What can I do for you?
Get Best Price

Get Best Price for 2050-46-6