Welcome to LookChem.com Sign In|Join Free
  • or
Home > Products >  > 

1,8-Diazacyclotetradecane-2,9-dione
Related Products

Hot Products

Basic Information Post buying leads Suppliers Cas Database
Name

1,8-Diazacyclotetradecane-2,9-dione

 EINECS N/A
CAS No. 56403-09-9 Density 0.97 g/cm3
PSA 65.18000 LogP 1.90500
Solubility N/A Melting Point 341 °C
Formula C12H22N2O2 Boiling Point 497.766 °C at 760 mmHg
Molecular Weight 226.319 Flash Point 204.11 °C
Transport Information N/A Appearance N/A
Safety Risk Codes N/A
Molecular Structure Molecular Structure of 56403-09-9 (1,8-Diazacyclotetradecane-2,9-dione) Hazard Symbols N/A
Synonyms

1,8-Diaza-2,9-dioxocyclotetradecane;2H-Azepin-2-one, hexahydro-, cyclic dimer;6-Aminohexanoate cyclic dimer;Caprolactam cyclic dimer;Caprolactam dimer;Cyclic dimer of e-caprolactam;Hexanoic acid,6-amino-, bimol. cyclic lactam;e-Aminocaproic acid cyclic dimer;e-Caprolactam cyclic dimer;

Article Data 7

1,8-Diazacyclotetradecane-2,9-dione Synthetic route

112507-71-8

13-benzyloxycarbonylamino-8-oxo-7-azatridecanoic acid hydrazide

56403-09-9

1,8-diazacyclotetradecane-2,9-dione

Conditions
ConditionsYield
ueber 6-<6-Amino-hexanoylamino>-hexansaeure-hydrazid-hydrobromid und das entsprechende Azid;
Multi-step reaction with 3 steps
1: 33percent HBr / acetic acid / 1 h / 20 °C
2: 1 M HCl, aq. NaNO2 / 0.25 h / 0 °C
3: aq. NaHCO3 / 4 h / 20 °C
View Scheme
2014-58-6

6-(6-aminohexanamido)hexanoic acid

541-41-3

chloroformic acid ethyl ester

56403-09-9

1,8-diazacyclotetradecane-2,9-dione

Conditions
ConditionsYield
With tributyl-amine

6-(6-Amino-hexanoylamino)-hexanoyl azide; hydrobromide

56403-09-9

1,8-diazacyclotetradecane-2,9-dione

Conditions
ConditionsYield
With sodium hydrogencarbonate at 20℃; for 4h; Yield given;
109565-05-1

6-(6-amino-hexanoylamino)-hexanoic acid-(4-nitro-phenyl ester); hydrobromide

56403-09-9

1,8-diazacyclotetradecane-2,9-dione

Conditions
ConditionsYield
With pyridine In N,N-dimethyl-formamide at 60℃; for 4h; Yield given;

6-(6-Amino-hexanoylamino)-hexanoic acid 4-nitro-phenyl ester; compound with trifluoro-acetic acid

56403-09-9

1,8-diazacyclotetradecane-2,9-dione

Conditions
ConditionsYield
With triethylamine In N,N-dimethyl-formamide at 60℃; for 4h; Yield given;
6-<6-amino-hexanoylamino>-hexanoic acid <2,4-dinitro-phenyl ester>-hydrobromide

6-<6-amino-hexanoylamino>-hexanoic acid <2,4-dinitro-phenyl ester>-hydrobromide

56403-09-9

1,8-diazacyclotetradecane-2,9-dione

Conditions
ConditionsYield
With tributyl-amine; N,N-dimethyl-formamide
6-<6-amino-hexanoylamino>-hexanoic acid <4-nitro-phenyl ester>-hydrobromide

6-<6-amino-hexanoylamino>-hexanoic acid <4-nitro-phenyl ester>-hydrobromide

56403-09-9

1,8-diazacyclotetradecane-2,9-dione

Conditions
ConditionsYield
With triethylamine; N,N-dimethyl-formamide
6-<6-amino-hexanoylamino>-hexanoyl chloride-hydrochloride

6-<6-amino-hexanoylamino>-hexanoyl chloride-hydrochloride

56403-09-9

1,8-diazacyclotetradecane-2,9-dione

Conditions
ConditionsYield
With triethylamine; N,N-dimethyl-formamide
51513-80-5

N-Boc-6-aminohexanoic acid N-hydroxysuccinimide ester

56403-09-9

1,8-diazacyclotetradecane-2,9-dione

Conditions
ConditionsYield
Multi-step reaction with 5 steps
1: 94 percent / 1,2-dimethoxy-ethane / 3 h
2: 100 percent / H2, AcOH / 10percent Pd/C / methanol / 1 h / 760 Torr
3: 90 percent / DCC / ethyl acetate / 3 h / 0 - 20 °C
4: 0.25 h / 50 °C
5: Et3N / dimethylformamide / 4 h / 60 °C
View Scheme
Multi-step reaction with 4 steps
1: 95 percent / aq. NaHCO3 / 1,2-dimethoxy-ethane / 3 h / Ambient temperature
2: 90 percent / DCC / ethyl acetate / 3 h / 0 - 20 °C
3: 0.25 h / 50 °C
4: Et3N / dimethylformamide / 4 h / 60 °C
View Scheme
6404-29-1

6-(tert-butoxycarbonylamino)hexanoic acid

56403-09-9

1,8-diazacyclotetradecane-2,9-dione

Conditions
ConditionsYield
Multi-step reaction with 6 steps
1: 55 percent / DCC / 1,2-dimethoxy-ethane / 20 h / 0 °C
2: 94 percent / 1,2-dimethoxy-ethane / 3 h
3: 100 percent / H2, AcOH / 10percent Pd/C / methanol / 1 h / 760 Torr
4: 90 percent / DCC / ethyl acetate / 3 h / 0 - 20 °C
5: 0.25 h / 50 °C
6: Et3N / dimethylformamide / 4 h / 60 °C
View Scheme
Multi-step reaction with 5 steps
1: 55 percent / DCC / 1,2-dimethoxy-ethane / 20 h / 0 °C
2: 95 percent / aq. NaHCO3 / 1,2-dimethoxy-ethane / 3 h / Ambient temperature
3: 90 percent / DCC / ethyl acetate / 3 h / 0 - 20 °C
4: 0.25 h / 50 °C
5: Et3N / dimethylformamide / 4 h / 60 °C
View Scheme

1,8-Diazacyclotetradecane-2,9-dione Specification

The 1,8-Diazacyclotetradecane-2,9-dione, with the CAS registry number 56403-09-9, is also known as 7,14-Diazacyclotetradecane-1,8-dione. This chemical's molecular formula is C12H22N2O2 and molecular weight is 226.32. What's more, its IUPAC name is the same with its product name.

Physical properties about 1,8-Diazacyclotetradecane-2,9-dione are: (1)ACD/LogP: -0.079; (2)# of Rule of 5 Violations: 0; (3)ACD/LogD (pH 5.5): -0.08; (4)ACD/LogD (pH 7.4): -0.08; (5)ACD/BCF (pH 5.5): 1.00; (6)ACD/BCF (pH 7.4): 1.00; (7)ACD/KOC (pH 5.5): 21.59; (8)ACD/KOC (pH 7.4): 21.59; (9)#H bond acceptors: 4; (10)#H bond donors: 2; (11)#Freely Rotating Bonds: 0; (12)Polar Surface Area: 58.2 Å2; (13)Index of Refraction: 1.446; (14)Molar Refractivity: 62.298 cm3; (15)Molar Volume: 233.421 cm3; (16)Polarizability: 24.697×10-24cm3; (17)Surface Tension: 30.377 dyne/cm; (18)Density: 0.97 g/cm3; (19)Flash Point: 204.11 °C; (20)Enthalpy of Vaporization: 76.581 kJ/mol; (21)Boiling Point: 497.766 °C at 760 mmHg; (22)Vapour Pressure: 0 mmHg at 25 °C.

You can still convert the following datas into molecular structure:
(1) SMILES: O=C1NCCCCCC(=O)NCCCCC1
(2) InChI: InChI=1S/C12H22N2O2/c15-11-7-3-1-5-9-13-12(16)8-4-2-6-10-14-11/h1-10H2,(H,13,16)(H,14,15)
(3) InChIKey: HERSSAVMHCMYSQ-UHFFFAOYSA-N

Post a RFQ

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

1

What can I do for you?
Get Best Price

Get Best Price for 56403-09-9