- 20,22-DIHYDRODIGITOXIN
- 20,29,30-Trinorlupane,(17alpha)-
- 20-ETHYL-6-β,8-DIHYDROXY-1-α-METHOXY-4-METHYLHETERATISAN-14-ONE
- 20-Ethylprostaglandin F2-alpha
- 20-Isopropylcholanthrene
- 20-METHYLCHOLANTHREN-15-ONE
- 20-METHYLCHOLANTHRENE PICRATE
- 20-METHYLCHOLANTHRENE-TRINITRO-BENZENE
- 20(S)-Ginsenoside C-K
- 2,10-DIFLUOROBENZO(rst)PENTAPHENE
- 626-04-01,3-Benzenedithiol
- 626-05-12,6-Dibromopyridine
- 62605-98-5Benzenamine,3-iodo-5-methoxy-
- 626-06-22(1H)-Pyridinone,6-hydroxy-
- 62607-26-5Acetamide,N-[5-[bis(2-methoxyethyl)amino]-2-[2-(2-iodo-4,6-dinitrophenyl)diazenyl]-4-methoxyphenyl]-
- 626-07-32,4(1H,3H)-Pyrimidinedione-2-14C(9CI)
- 62607-69-610-Phenyl-1-decanol
- 62608-15-59H-Carbazole,3,3'-(1,4-phenylenedi-2,1-ethenediyl)bis[9-ethyl-
- 626-08-41,2,4-Triazin-5(2H)-one,3,4-dihydro-3-thioxo-
- 62609-86-34-Oxo-3-phenyl-2-thioxoimidazolidine-1-acetic acid
Hot Products
- 104987-11-3Tacrolimus
- 141-53-7Sodium formate
- 8001-54-5Quaternary ammonium compounds, alkylbenzyldimethyl, chlorides
- 9003-39-8Povidone
- 10161-34-9Trenbolone acetate
- 402957-28-2Telaprevir
- 68-19-9Cyanocobalamin
- 7631-86-9Silicon dioxide
- 302-79-4Tretinoin
- 77-92-9Citric acid
|
Basic Information |
|
Post buying leads |
|
Suppliers |
|
Cas Database |
| Name |
2,4-Dihydroxypyridine |
EINECS | 210-924-8 |
| CAS No. | 626-03-9 | Density | 1.379 g/cm3 |
| PSA | 53.35000 | LogP | 0.49280 |
| Solubility | 6.211g/L(20 oC) | Melting Point |
272-276 °C(lit.) |
| Formula | C5H5NO2 | Boiling Point | 270.9 °C at 760 mmHg |
| Molecular Weight | 111.1 | Flash Point | 117.6 °C |
| Transport Information | N/A | Appearance | white to yellow-beige crystals or cryst. powder |
| Safety | 26-36-37/39 | Risk Codes | 36/37/38 |
| Molecular Structure |
|
Hazard Symbols |
 Xi
|
| Synonyms |
2(1H)-Pyridone, 4-hydroxy-;2(1H)-Pyridinone, 4-hydroxy-;2-hydroxy-1H-pyridin-4-one;2(1H)-Pyridinone, 4-hydroxy- (9CI);4-Hydroxy-2(1H)-pyridinone;4-Hydroxy-2-pyridone;3-Deazauracil;Pyridine-2,4-diol; |
Article Data | 10 |
2,4-Dihydroxypyridine Synthetic route
- 18677-43-5
2,4-dimethoxypyridine
- 626-03-9
3-deazauracil
| Conditions | Yield |
|---|---|
| With hexamethyldisilathiane; sodium methylate In various solvent(s) at 180℃; for 24h; | 75% |
| Conditions | Yield |
|---|---|
| With sodium hydroxide at 290 - 310℃; |
- 626-03-9
3-deazauracil
| Conditions | Yield |
|---|---|
| With hydrogenchloride |
- 626-03-9
3-deazauracil
| Conditions | Yield |
|---|---|
| With hydrogenchloride at 190 - 200℃; |
- 626-03-9
3-deazauracil
| Conditions | Yield |
|---|---|
| With hydrogenchloride at 190 - 200℃; |
| Conditions | Yield |
|---|---|
| Multi-step reaction with 2 steps 1: H2SO4 / Behandeln des Reaktionsgemisches mit wss. NaNO2 2: concentrated aqueous hydrochloric acid View Scheme |
- 19867-18-6
6-chloro-2,4-dihydroxy-nicotinonitrile
- 626-03-9
3-deazauracil
| Conditions | Yield |
|---|---|
| Multi-step reaction with 3 steps 1: zinc-powder; aqueous H2SO4 2: H2SO4 / Behandeln des Reaktionsgemisches mit wss. NaNO2 3: concentrated aqueous hydrochloric acid View Scheme |
- 626-03-9
3-deazauracil
- 89282-12-2
2,4-dihydroxy-3-nitropyridine
| Conditions | Yield |
|---|---|
| With sulfuric acid; nitric acid at 0℃; Industrial scale; | 98% |
| With sulfuric acid; nitric acid at 0℃; for 0.75h; | 96% |
| With nitric acid at 90℃; for 3h; | 92% |
- 626-03-9
3-deazauracil
- 96245-97-5
3-bromo-2,4-dihydroxypyridine
| Conditions | Yield |
|---|---|
| With hydrogen bromide; bromine; acetic acid In water at 0℃; for 0.5h; | 96% |
| With hydrogen bromide; bromine In acetic acid | 95% |
| With hydrogen bromide; bromine; acetic acid |
| Conditions | Yield |
|---|---|
| With phosphorus(V) oxybromide at 125℃; for 4.5h; | A 90% B 9% |
| With phosphorus(V) oxybromide at 125℃; for 4.5h; | A 85% B 12% |
2,4-Dihydroxypyridine Chemical Properties
.jpg)
IUPAC Name: 2-Hydroxy-1H-pyridin-4-one
Molecular Formula: C5H5NO2
Molecular Weight: 111.10 g/mol
Canonical SMILES: c1c(ccnc1O)O
InChI: InChI=1/C5H5NO2/c7-4-1-2-6-5(8)3-4/h1-3H,(H2,6,7,8)
EINECS: 210-924-8
Product Categories: Pyridines; Pyridine; Pyridines derivates; Aromatics Compounds; Aromatics;Bases & Related Reagents; Nucleotides
H-Bond Donor: 2
H-Bond Acceptor: 3
Tautomer Count: 9
Exact Mass: 111.032028
MonoIsotopic Mass: 111.032028
Topological Polar Surface Area: 49.3
Heavy Atom Count: 8
Complexity: 169
Index of Refraction: 1.593
Molar Refractivity: 27.33 cm3
Molar Volume: 80.5 cm3
Polarizability: 10.83×10-24 cm3
Surface Tension: 58.2 dyne/cm
Density: 1.379 g/cm3
Flash Point: 117.6 °C
Enthalpy of Vaporization: 59.11 kJ/mol
Boiling Point: 270.9 °C at 760 mmHg
Melting Point: 272-276 °C(lit.)
Water Solubility: 6250 mg/L at 20 °C
Atmospheric OH Rate Constant: 1.08E-10 cm3/molecule-sec at 25 °C
Vapour Pressure of 2,4-Dihydroxypyridine (CAS NO.626-03-9): 0.000873 mmHg at 25 °C
2,4-Dihydroxypyridine Toxicity Data With Reference
| Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
|---|---|---|---|---|---|
| mouse | LD50 | intraperitoneal | 4895mg/kg (4895mg/kg) | Toxicon. Vol. 23, Pg. 815, 1985. |
2,4-Dihydroxypyridine Safety Profile
Hazard Codes: 
Xi
Risk Statements: 36/37/38
R36/37/38: Irritating to eyes, respiratory system and skin.
Safety Statements: 26-36-37/39
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36: Wear suitable protective clothing.
S37/39: Wear suitable gloves and eye/face protection.
WGK Germany: 3
RTECS: UV1146800
Hazard Note: Irritant
HazardClass of 2,4-Dihydroxypyridine (CAS NO.626-03-9): Irritant
2,4-Dihydroxypyridine Specification
2,4-Dihydroxypyridine (CAS NO.626-03-9), its Synonyms are 2(1H)-Pyridinone, 4-hydroxy- (9CI) ; 2(1H)-Pyridone, 4-hydroxy- ; 4-Hydroxy-2-pyridone ; 2,4-Pyridinediol ; 3-Deazauracil ; 4-Hydroxy-2(1H)-pyridinone . It is white to yellow-beige crystals or cryst. powder.
What can I do for you?
Get Best Price
