Basic Information | Post buying leads | Suppliers | Cas Database |
Conditions | Yield |
---|---|
With bromine In dichloromethane; water | 90% |
With bromine In dichloromethane; water | 90% |
With bromine In dichloromethane; water | 90% |
4-bromo-2-fluorophenol
Conditions | Yield |
---|---|
Stage #1: 2-(2-fluoro-4-bromophenoxy)pyridine With methyl trifluoromethanesulfonate In toluene at 100℃; for 2h; Inert atmosphere; Stage #2: With sodium ethanolate for 1h; Reflux; Inert atmosphere; | 82% |
Stage #1: 2-(2-fluoro-4-bromophenoxy)pyridine With methyl trifluoromethanesulfonate In toluene at 100℃; Stage #2: With methanol; sodium at 90℃; | 76% |
Conditions | Yield |
---|---|
With acetic acid; Selectfluor; eosin y In water at 20℃; for 6h; Irradiation; Green chemistry; | 68% |
2-fluorophenol
A
4-bromo-2-fluorophenol
B
2,4-dibromo-6-fluorophenol
C
2-bromo-6-fluorophenol
Conditions | Yield |
---|---|
With 4-morpholineethanesulfonic acid; VBrPO(AnI) bromoperoxidase; dihydrogen peroxide; sodium bromide In water; tert-butyl alcohol at 23℃; pH=6.2; Overall yield = 37 %; | A n/a B 18% C n/a |
Conditions | Yield |
---|---|
With hydrogen bromide at 190℃; |
Conditions | Yield |
---|---|
2., HBr, CuBr; Yield given. Multistep reaction; |
Conditions | Yield |
---|---|
With microsomal protein; NADPH In phosphate buffer at 37℃; for 0.166667h; pH=7.6; Enzyme kinetics; Oxidation; |
Conditions | Yield |
---|---|
With formic acid; fluorine at 10℃; for 1.75h; Fluorination; Title compound not separated from byproducts; | A 22 % Spectr. B 4 % Spectr. |
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1: 98.5 percent / hydrogen / 5percent Pd/C / ethyl acetate / 24 h / 760 Torr 2: 2., HBr, CuBr View Scheme |
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1: sulfuric acid; aqueous sodium nitrite solution / Behandeln des Reaktionsgemisches mit Kupfer(I)-bromid und wss. Bromwasserstoffsaeure 2: aqueous hydrobromic acid / 190 °C View Scheme |
Molecular Structure of 2-Fluoro-4-bromophenol(2105-94-4):
IUPAC Name:4-bromo-2-fluorophenol
Molecular Formula:C6H4BrFO
Molecular Weight:190.997763 g/mol
Appearance:clear colorless to slightly yellow liquid
Density:1.764 g/cm3
Flash Point:98.9 °C
Enthalpy of Vaporization:46.04 kJ/mol
Boiling Point:206.1 °C at 760 mmHg
Vapour Pressure:0.168 mmHg at 25 °C
Water Solubility:1105 mg/L at 25 °C
Refractive index:n20/D 1.566(lit.)
Synonyms of 2-Fluoro-4-bromophenol(2105-94-4):
4-BROMO-2-FLUOROPHENOL;2-Fluoro-4-Bromophenol;4-Bromo-2-fluorophenol 98%;4-Bromo-2-fluorophenol98%;4-Bromo-2-fluorophenol, 97+%
Categories of 2-Fluoro-4-bromophenol(2105-94-4):
Fluorobenzene Series;Aromatic Phenols;Fluorobenzene;Phenol&Thiophenol&Mercaptan;Bromine Compounds;Fluorine Compounds;Phenols;Building Blocks for Liquid Crystals;Functional Materials;Phenols(Building Blocks for Liquid Crystals);Organic Building Blocks;Oxygen Compounds
Safety Information of 2-Fluoro-4-bromophenol(2105-94-4):
Hazard Codes:Xi,Xn
Hazard Note:Irritant
Risk Statements:36/37/38-22
36/37/38:Irritating to eyes, respiratory system and skin
22:Harmful if swallowed
Safety Statements:26-37/39-36/37/39
26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
37/39:Wear suitable gloves and eye/face protection
36/37/39:Wear suitable protective clothing, gloves and eye/face protection
WGK Germany:3
First Aid Measures of 2-Fluoro-4-bromophenol(2105-94-4):
Eyes:Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.
Skin:Get medical aid. Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes.
Ingestion:Get medical aid. Wash mouth out with water.
Inhalation:Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
Storage of 2-Fluoro-4-bromophenol(2105-94-4):
Store in a cool, dry place. Store in a tightly closed container.