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4-Ethylbenzenesulfonamide

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Name

4-Ethylbenzenesulfonamide

EINECS 680-161-7
CAS No. 138-38-5 Density 1.225 g/cm3
PSA 68.54000 LogP 2.67750
Solubility N/A Melting Point 111 °C
Formula C8H11NO2S Boiling Point 329.658 °C at 760 mmHg
Molecular Weight 185.247 Flash Point 153.172 °C
Transport Information N/A Appearance N/A
Safety Risk Codes N/A
Molecular Structure Molecular Structure of 138-38-5 (4-Ethylbenzenesulfonamide) Hazard Symbols Xi
Synonyms

Benzenesulfonamide,p-ethyl- (6CI,7CI,8CI);4-Ethylbenzenesulfonamide;EBSA;NSC 9909;p-Ethylbenzenesulfonamide;

Article Data 14

4-Ethylbenzenesulfonamide Synthetic route

97-94-9

triethyl borane

701-34-8

4-bromo-benzenesulfonic acid amide

138-38-5

4-ethylbenzenesulfonamide

Conditions
ConditionsYield
With (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; caesium carbonate In tetrahydrofuran Suzuki coupling; Inert atmosphere; Reflux; chemoselective reaction;88%
With (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; caesium carbonate In tetrahydrofuran Suzuki-Miyaura cross-coupling; Inert atmosphere; Reflux;88%
110955-51-6

4-Ethyl-N-isopropylidene-benzenesulfonamide

A

138-38-5

4-ethylbenzenesulfonamide

B

67-64-1

acetone

Conditions
ConditionsYield
With water for 1h; Heating;A 77%
B n/a
17988-51-1

1-Ethyl-3-trimethylsilylbenzol

138-38-5

4-ethylbenzenesulfonamide

Conditions
ConditionsYield
With chlorure d'aluminium; chlorure de sulfamoyle In dichloromethane for 15h; Ambient temperature;38%
16712-69-9

p-ethylbenzenesulfonyl chloride

138-38-5

4-ethylbenzenesulfonamide

Conditions
ConditionsYield
With ammonia at 20 - 100℃;9.5%
With ammonia
With ammonium hydroxide at 40℃; for 0.5h;
With ammonium hydroxide for 2h; Large scale;450 kg
With pyridine; ammonium hydroxide In dichloromethane at 0 - 20℃; for 4h;
100-41-4

ethylbenzene

A

66294-51-7

4,4'-sulfonylbis(1-ethylbenzene)

B

138-38-5

4-ethylbenzenesulfonamide

Conditions
ConditionsYield
With chlorosulphuric acid; chloroform Erwaermen des Reaktionsprodukts mit Ammoniumcarbonat;
1-ethyl-benzene-sulfonyl fluoride-(4)

1-ethyl-benzene-sulfonyl fluoride-(4)

138-38-5

4-ethylbenzenesulfonamide

Conditions
ConditionsYield
With ammonia

N-chloro-N-sodio-p-ethylbenzenesulfonamide

138-38-5

4-ethylbenzenesulfonamide

Conditions
ConditionsYield
With sodium hydroxide; D-Fructose In water at 29.85℃; Kinetics; Further Variations:; pH-values; Reagents; ionic strength values;
128254-32-0

2-Ethyl-1,4-bis-trimethylsilanyl-benzene

138-38-5

4-ethylbenzenesulfonamide

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 100 percent / acide trifluoroacetique / CCl4 / 15 h / Heating
2: 38 percent / chlorure d'aluminium, chlorure de sulfamoyle / CH2Cl2 / 15 h / Ambient temperature
View Scheme
1336-21-6

ammonium hydroxide

16712-69-9

p-ethylbenzenesulfonyl chloride

138-38-5

4-ethylbenzenesulfonamide

Conditions
ConditionsYield
With sulfuric acid; trichlorophosphate In ethylbenzene; water
138-38-5

4-ethylbenzenesulfonamide

189999-35-7

[1,1'-biphenyl]-2,2'-iodonium trifluoromethanesulfonate

1469876-05-8

9-((4-ethylphenyl)sulfonyl)-9H-carbazole

Conditions
ConditionsYield
With copper diacetate; sodium carbonate In ethylene glycol; isopropyl alcohol at 90℃; for 16h; Inert atmosphere;100%
With copper diacetate; sodium carbonate; ethylene glycol In isopropyl alcohol at 85℃; for 16h; Ullmann Condensation; Inert atmosphere;74%
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