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ANTHRAMYCIN METHYL ETHER

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ANTHRAMYCIN METHYL ETHER

EINECS N/A
CAS No. 5544-25-2 Density 1.349g/cm3
PSA N/A LogP N/A
Solubility N/A Melting Point N/A
Formula C17H19N3O4•H2O Boiling Point 309.7°Cat760mmHg
Molecular Weight 329.356 Flash Point 141.1°C
Transport Information N/A Appearance N/A
Safety Poison by ingestion, subcutaneous, and intraperitoneal routes. When heated to decomposition it emits toxic fumes of NOx. Risk Codes N/A
Molecular Structure Molecular Structure of 5544-25-2 ((2E)-3-[(11R,11aS)-9-hydroxy-11-methoxy-8-methyl-5-oxo-5,10,11,11a-tetrahydro-1H-pyrrolo[2,1-c][1,4]benzodiazepin-2-yl]prop-2-enamide) Hazard Symbols N/A
Synonyms

N/A

Article Data 2

ANTHRAMYCIN METHYL ETHER Chemical Properties

Product Name: Anthramycin methyl ether (CAS NO.5544-25-2)


Molecular Formula: C17H19N3O4
Molecular Weight: 329.3505g/mol
Mol File: 5544-25-2.mol
Boiling point: 631.8 °C at 760 mmHg
Flash Point: 335.9 °C
Density: 1.4 g/cm3
Surface Tension: 70.6 dyne/cm
Enthalpy of Vaporization: 96.84 kJ/mol
Vapour Pressure: 1.47E-16 mmHg at 25°C
XLogP3-AA: 0.5
H-Bond Donor: 3
H-Bond Acceptor: 5

ANTHRAMYCIN METHYL ETHER Toxicity Data With Reference

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intraperitoneal 730mg/kg (730mg/kg)   Journal of Antibiotics. Vol. 33, Pg. 54, 1980.
mouse LD50 oral 3400ug/kg (3.4mg/kg)   "Proceedings of the International Symposium on Chemotherapy of Cancer, Lugano, Switzerland, 1964," Plattner, P.A., ed., New York, American Elsevier Pub. Co., 1964Vol. -, Pg. 303, 1964.
mouse LD50 subcutaneous 2900ug/kg (2.9mg/kg)   "Proceedings of the International Symposium on Chemotherapy of Cancer, Lugano, Switzerland, 1964," Plattner, P.A., ed., New York, American Elsevier Pub. Co., 1964Vol. -, Pg. 303, 1964.

ANTHRAMYCIN METHYL ETHER Safety Profile

Poison by ingestion, subcutaneous, and intraperitoneal routes. When heated to decomposition it emits toxic fumes of NOx.

ANTHRAMYCIN METHYL ETHER Specification

 Anthramycin methyl ether ,its CAS NO. is 5544-25-2,the synonyms is Anthramycin 11-methyl ether ; Antibiotic A ; B 89006 ; NSC 106408 ; Roche 5-9000 ; 1H-Pyrrolo(2,1-c)(1,4)benzodiazepine-2-acrylamide, 5,10,11,11a-tetrahydro-9-hydroxy-11-methoxy-8-methyl-5-oxo-, (E)- ; 2-Propenamide, 3-(5,10,11,11a-tetrahydro-9-hydroxy-11-methoxy-8-methyl-5-oxo-1H-pyrrolo(2,1-c)(1,4)benzodiazepin-2-yl)-, (11R-(2(E),11alpha,11abeta))- .

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