- Benzene
- Benzene, (10-bromodecyl)-
- Benzene,1,1',1'',1'''-(oxydimethylidyne)tetrakis-
- Benzene,1,1',1'',1'''-silanetetrayltetrakis-
- Benzene,1,1',1'',1'''-silanetetrayltetrakis[4-methyl-
- Benzene,1,1'-[1,2-bis(methylene)-1,2-ethanediyl]bis-
- Benzene,1,1'-(1,2-cyclopropanediyl)bis-
- Benzene,1,1'-(1,2-ethanediyl)bis(2,4-dinitro-)
- Benzene,1,1'-(1,2-ethanediyl)bis[2-methyl-
- Benzene,1,1'-(1,2-ethanediyl)bis[4-methyl-
- 64248-61-9Benzene,2,4-difluoro-1-(trifluoromethyl)-
- 64248-62-03,4-Difluorobenzonitrile
- 64248-63-13,5-Difluorobenzonitrile
- 64248-64-2Benzonitrile,2,5-difluoro-
- 6424-88-0Benzoicacid, 3-[(4-amino-9,10-dihydro-9,10-dioxo-3-sulfo-1-anthracenyl)amino]-,1-ethyl ester, sodium salt (1:1)
- 6424-89-1Benzoic acid,5-[[3-[(4-amino-9,10-dihydro-9,10-dioxo-3-sulfo-1-anthracenyl)amino]benzoyl]amino]-2-hydroxy-,sodium salt (1:1)
- 64249-01-0Phosphorodithioic acid,S-[2-[(4-chlorophenyl)(1-methylethyl)amino]-2-oxoethyl] O,O-dimethyl ester
- 642494-36-81H-Indole,6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-
- 642494-37-91H-Indole,7-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-
- 6425-01-0Tetrasodium 4,8-diamino-1,5-dioxido-9,10-dioxo-9,10-dihydroanthracene-2,6-disulfonate
Hot Products
- 104987-11-3Tacrolimus
- 141-53-7Sodium formate
- 8001-54-5Quaternary ammonium compounds, alkylbenzyldimethyl, chlorides
- 9003-39-8Povidone
- 10161-34-9Trenbolone acetate
- 402957-28-2Telaprevir
- 68-19-9Cyanocobalamin
- 7631-86-9Silicon dioxide
- 302-79-4Tretinoin
- 77-92-9Citric acid
|
Basic Information |
|
Post buying leads |
|
Suppliers |
|
Cas Database |
| Name |
Benzene,1,3-difluoro-2-(trifluoromethyl)- |
EINECS | N/A |
| CAS No. | 64248-60-8 | Density | 1.386 g/cm3 |
| PSA | 0.00000 | LogP | 2.98360 |
| Solubility | N/A | Melting Point |
N/A |
| Formula | C7H3F5 | Boiling Point | 121 °C at 760 mmHg |
| Molecular Weight | 182.093 | Flash Point | 32.7 °C |
| Transport Information | N/A | Appearance | N/A |
| Safety | Risk Codes | N/A | |
| Molecular Structure |
|
Hazard Symbols |
 Xi
|
| Synonyms |
2,6-Difluorobenzotrifluoride; |
Article Data | 3 |
Benzene,1,3-difluoro-2-(trifluoromethyl)- Synthetic route
- 112860-78-3
3,5-dichloro-2,6-difluorobenzotrifluoride
- 64248-60-8
1,3-difluoro-2-(trifluoromethyl)benzene
| Conditions | Yield |
|---|---|
| With sodium acetate In water; acetic acid |
- 5509-65-9
2,6-difluoroaniline
- 77152-08-0
trifluoromethylcopper(I)
A
- 372-18-9
1,3-Difluorobenzene
B
- 64248-60-8
1,3-difluoro-2-(trifluoromethyl)benzene
| Conditions | Yield |
|---|---|
| Stage #1: 2,6-difluoroaniline With hydrogen fluoride; sodium nitrite In water; acetonitrile at 0℃; Inert atmosphere; Stage #2: trifluoromethylcopper(I) In water; N,N-dimethyl-formamide; acetonitrile at 0℃; for 0.25h; Inert atmosphere; Overall yield = 27 %Spectr.; |
- 110-85-0
piperazine
- 64248-60-8
1,3-difluoro-2-(trifluoromethyl)benzene
- 946399-80-0
1-(3-fluoro-2-(trifluoromethyl)phenyl)piperazine
| Conditions | Yield |
|---|---|
| at 90℃; for 16h; | 73.4% |
- 124-38-9
carbon dioxide
- 64248-60-8
1,3-difluoro-2-(trifluoromethyl)benzene
| Conditions | Yield |
|---|---|
| Stage #1: 1,3-difluoro-2-(trifluoromethyl)benzene With n-butyllithium In tetrahydrofuran; diethyl ether at -70 - -65℃; for 1h; Stage #2: carbon dioxide In tetrahydrofuran; diethyl ether at -65 - 30℃; for 5h; Stage #3: With hydrogenchloride In tetrahydrofuran; diethyl ether; water | 72% |
- 64248-60-8
1,3-difluoro-2-(trifluoromethyl)benzene
- 952233-12-4
(3-Fluoro-2-trifluoromethyl-phenyl)-hydrazine hydrochloride
| Conditions | Yield |
|---|---|
| With hydrazine In dimethyl sulfoxide at 20℃; for 16h; | 67% |
- 64248-60-8
1,3-difluoro-2-(trifluoromethyl)benzene
- 68-12-2, 33513-42-7
N,N-dimethyl-formamide
| Conditions | Yield |
|---|---|
| Stage #1: 1,3-difluoro-2-(trifluoromethyl)benzene With n-butyllithium In tetrahydrofuran; cyclohexane at -70℃; for 0.5h; Inert atmosphere; Stage #2: N,N-dimethyl-formamide In tetrahydrofuran; cyclohexane at -70℃; for 2h; | 65% |
| Conditions | Yield |
|---|---|
| With potassium phosphate In N,N-dimethyl-formamide at 135℃; for 72h; | 40% |
- 64248-60-8
1,3-difluoro-2-(trifluoromethyl)benzene
| Conditions | Yield |
|---|---|
| Stage #1: 1,3-difluoro-2-(trifluoromethyl)benzene With sodium hydride In N,N-dimethyl-formamide; mineral oil at 20℃; for 0.5h; Stage #2: 2,3-dihydroimidazo[1,2-c]quinazolin-9-ol In N,N-dimethyl-formamide; mineral oil at 20℃; | 37% |
- 64248-60-8
1,3-difluoro-2-(trifluoromethyl)benzene
- 123973-36-4
1,3-difluoro-4-nitro-2-(trifluoromethyl)benzene
| Conditions | Yield |
|---|---|
| With sulfuric acid; nitric acid | |
| With sulfuric acid; nitric acid In dichloromethane |
- 1217349-81-9
5-(benzyloxy)-3H-imidazo[4,5-b]pyridine
- 64248-60-8
1,3-difluoro-2-(trifluoromethyl)benzene
- 1217350-42-9
5-(benzyloxy)-3-(3-fluoro-2-(trifluoromethyl)phenyl)-3H-imidazo[4,5-b]pyridine
| Conditions | Yield |
|---|---|
| With caesium carbonate In N,N-dimethyl-formamide at 80℃; |
Benzene,1,3-difluoro-2-(trifluoromethyl)- Specification
The Benzene,1,3-difluoro-2-(trifluoromethyl)-, with the CAS registry number 64248-60-8, is also known as 2,6-Difluorobenzotrifluoride. This chemical's molecular formula is C7H3F5 and molecular weight is 182.0907. Its systematic name is called 1,3-difluoro-2-(trifluoromethyl)benzene. When you are using this chemical, please be cautious about it, it may cause inflammation to the skin or other mucous membranes.
Physical properties of Benzene,1,3-difluoro-2-(trifluoromethyl)-: (1)ACD/LogP: 2.98; (2)# of Rule of 5 Violations: 0; (3)ACD/LogD (pH 5.5): 2.98; (4)ACD/LogD (pH 7.4): 2.98; (5)ACD/BCF (pH 5.5): 107.8; (6)ACD/BCF (pH 7.4): 107.8; (7)ACD/KOC (pH 5.5): 992.12; (8)ACD/KOC (pH 7.4): 992.12; (9)Index of Refraction: 1.391; (10)Molar Refractivity: 31.22 cm3; (11)Molar Volume: 131.3 cm3; (12)Surface Tension: 20.2 dyne/cm; (13)Density: 1.386 g/cm3; (14)Flash Point: 32.7 °C; (15)Enthalpy of Vaporization: 34.43 kJ/mol; (16)Boiling Point: 121 °C at 760 mmHg; (17)Vapour Pressure: 17.8 mmHg at 25°C.
You can still convert the following datas into molecular structure:
(1)SMILES: FC(F)(F)c1c(F)cccc1F
(2)InChI: InChI=1/C7H3F5/c8-4-2-1-3-5(9)6(4)7(10,11)12/h1-3H
(3)InChIKey: NKKFHDNJRMWBFS-UHFFFAOYAK
What can I do for you?
Get Best Price
