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Bis(trifluoromethyl)disulfide

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Name

Bis(trifluoromethyl)disulfide

EINECS N/A
CAS No. 372-64-5 Density 1.653g/cm3
PSA 50.60000 LogP 3.40740
Solubility N/A Melting Point N/A
Formula C2F6 S2 Boiling Point 34.6°Cat760mmHg
Molecular Weight 202.144 Flash Point °C
Transport Information N/A Appearance N/A
Safety Mixtures of the solid with chlorine mono- or tri- fluorides are explosive. Dilute with halogenated solvents. When heated to decomposition it emits toxic fumes of F and SOx. See also SULFIDES. Risk Codes 23/24/25
Molecular Structure Molecular Structure of 372-64-5 (BIS(TRIFLUOROMETHYL)DISULFIDE) Hazard Symbols
Synonyms

Bis(trifluoromethyl)disulfide; Perfluorodimethyl disulfide; Trifluoromethyl disulfide

Article Data 164

Bis(trifluoromethyl)disulfide Synthetic route

21259-75-6

mercury bis(trifluoromethanethiolate)

A

372-64-5

Bis(trifluoromethyl)disulfid

B

trifluoromethylthio-mercury(II) chloride

C

83665-28-5

bis(trifluoromethylthio)tellurium

Conditions
ConditionsYield
With tellurium tetrachloride for 1h; Heating;A n/a
B n/a
C 83%
2314-97-8

iodotrifluoromethane

7704-34-9

sulfur

372-64-5

Bis(trifluoromethyl)disulfid

Conditions
ConditionsYield
390-420°C, atm. pessure in a continuous flow system;80.6%
390-420°C, atm. pessure in a continuous flow system;80.6%
>200°C, in autoclave;
>200°C, in autoclave;
79378-29-3

O,O-diethyl S-trifluoromethyl phosphorothioate

A

420-32-6

thiocarbonyl fluoride

B

358-74-7

diethyl fluorophosphate

C

372-64-5

Bis(trifluoromethyl)disulfid

Conditions
ConditionsYield
With triethylamine In dichloromethane at 10℃; for 0.166667h;A n/a
B 76%
C n/a
21259-75-6

mercury bis(trifluoromethanethiolate)

13360-57-1

dimethylamino sulfonyl chloride

A

372-64-5

Bis(trifluoromethyl)disulfid

B

N,N-Dimethyl-S-(trifluormethyl)thiosulfamidsaeure

Conditions
ConditionsYield
In acetonitrileA n/a
B 76%
7664-39-3

hydrogen fluoride

594-42-3

chlorothio-trichloro-methane

A

421-17-0

Trifluoromethylsulfenyl chloride

B

372-64-5

Bis(trifluoromethyl)disulfid

C

358-15-6

Trifluoro-methanethiosulfonic acid S-trifluoromethyl ester

Conditions
ConditionsYield
180°C; chrom oxide fluoride catalyst;A 74%
B n/a
C n/a
676-71-1

dimethyl(bromo)arsine

3872-23-9

Copper(I) trifluoromethanethiolate

A

372-64-5

Bis(trifluoromethyl)disulfid

B

372-06-5

bis(trifluoromethyl)trisulfide

C

372-07-6

bis(trifluoromethyl)tetrasulfide

D

1959-80-4

dimethyl(trifluoromethylthio)arsine

Conditions
ConditionsYield
at 80 - 90℃; for 6h; Further byproducts given;A n/a
B n/a
C n/a
D 70%
421-17-0

Trifluoromethylsulfenyl chloride

108-88-3

toluene

A

372-64-5

Bis(trifluoromethyl)disulfid

B

351-60-0

benzyl trifluoromethyl sulfide

C

100-44-7

benzyl chloride

Conditions
ConditionsYield
byproducts: HCl; Irradiation (UV/VIS);A n/a
B 70%
C 3%
byproducts: HCl; Irradiation (UV/VIS);A n/a
B 70%
C 3%
for 0.283333h; Mechanism; Irradiation; effect of bis(heptafluoro-n-propyl) disulfide;

potassium fluoride

594-42-3

chlorothio-trichloro-methane

372-64-5

Bis(trifluoromethyl)disulfid

Conditions
ConditionsYield
With hydrogen bromide In further solvent(s) 160-175°C; solvent: tetramethylenesulfone;68%
With HBr In further solvent(s) 160-175°C; solvent: tetramethylenesulfone;68%

potassium fluoride

15110-08-4

Bis(trichloromethyl)disulfane

372-64-5

Bis(trifluoromethyl)disulfid

Conditions
ConditionsYield
In further solvent(s) 150-160°C; solvent: tetramethylenesulfone;58%
In further solvent(s) 150-160°C; solvent: tetramethylenesulfone;58%
3042-22-6

2-phenyl-1H-pyrrole

1443036-49-4

1-phenyl-2-(phenyl-λ3-iodaneylidene)-2-((trifluoromethyl)sulfonyl)ethan-1-one

A

372-64-5

Bis(trifluoromethyl)disulfid

B

2-phenyl-5-((trifluoromethyl)thio)-1H-pyrrole

Conditions
ConditionsYield
Stage #1: 1-phenyl-2-(phenyl-λ3-iodaneylidene)-2-((trifluoromethyl)sulfonyl)ethan-1-one With copper (II)-fluoride In 1-methyl-pyrrolidin-2-one at 20℃; for 0.333333h;
Stage #2: 2-phenyl-1H-pyrrole at 20℃; for 5h; regioselective reaction;
A 28%
B 58%

Bis(trifluoromethyl)disulfide Chemical Properties

 Bis(trifluoromethyl)disulfide ,its CAS register number is 372-64-5,it's also named as Bis(trifluoromethyl)-disulfid ; Di(methyl) disulfide, perfluoro- ; Di(Trifluoromethyl)disulfide ; Disulfide, bis(trifluoromethyl) ; Hexafluorodimethyldisulfide ; Perfluorodimethyl disulfide;perfluorodimethyldisulfide ; Trifluoromethyl disulfide ; CID67795 ; ZINC04329251 ; LS-63073 ,and so on.

IUPAC Name: Trifluoro(trifluoromethyldisulfanyl)methane
CAS: 372-64-5
Molecular Formula: C2F6S2
Molecular Weight: 202.14
Molecular structure:
ACD/LogD (pH 5.5): 5.75 
ACD/LogD (pH 7.4): 5.75 
ACD/BCF (pH 5.5): 13799.75 
ACD/BCF (pH 7.4): 13799.75 
ACD/KOC (pH 5.5): 31982.18 
ACD/KOC (pH 7.4): 31982.18 
H bond acceptors: 0 
H bond donors: 0 
Freely Rotating Bonds: 1 
Index of Refraction: 1.378 
Molar Refractivity: 28.22 cm3 
Molar Volume: 122.2 cm3 
Polarizability: 11.18 10-24cm3 
Surface Tension: 20.5 dyne/cm 
Density: 1.653 g/cm3 
Enthalpy of Vaporization: 26.81 kJ/mol 
Boiling Point: 34.6 °C at 760 mmHg 
Vapour Pressure: 538 mmHg at 25°C 

Bis(trifluoromethyl)disulfide Uses

  Bis(trifluoromethyl)disulfide (CAS No.372-64-5) is commonly used as chemical reagent.

Bis(trifluoromethyl)disulfide Safety Profile

Mixtures of the solid with chlorine mono- or tri- fluorides are explosive. Dilute with halogenated solvents. When heated to decomposition it emits toxic fumes of F and SOx.

Hazard Codes:  T
Risk Statements:  23/24/25 (R23/24/25:Toxic by inhalation, in contact with skin and if swallowed.)
Safety Statements:  23-36/37/39-45 (S23:Do not breathe vapour. S36/37/39:Wear suitable protective clothing, gloves and eye/face protection. S45:In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.))
RIDADR:  2810
Hazard Note:  Highly Toxic

Bis(trifluoromethyl)disulfide Specification

Removal in wastewater treatment of Bis(trifluoromethyl)disulfide (CAS No.372-64-5) can be stated as follows:
Total removal:96.99  percent
Total biodegradation:0.06  percent
Total sludge adsorption:12.51  percent
Total to Air:84.42  percent
(using 10000 hr Bio P,A,S)

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