100678-82-8

Basic information

• Product Name: Ethyl 2-((1S,2R)-2-hydroxy-1,2-diphenylethylamino)acetate
• Synonyms: n-[(1s,2r)-2-hydroxy-1,2-diphenylethyl]-glycine ethyl ester;Ethyl 2-((1S,2R)-2-hydroxy-1,2-diphenylethylamino)acetate
• CAS NO: 100678-82-8
• Molecular Formula: C₁₈H₂₁NO₃
• Molecular Weight: 299.36
• Product Categories: Amines, Heterocycles, Pharmaceuticals, Intermediates & Fine Chemicals
• Mol File: 100678-82-8.mol

Chemical Properties

• Melting Point: 127-128°C
• Boiling Point: 436°C
• Flash Point: 217.2°C
• Appearance: White crystalline powder
• Density: 1.150
• Vapor Pressure: 2.33E-08mmHg at 25°C
• Refractive Index: 1.572
• CAS DataBase Reference: Ethyl 2-((1S,2R)-2-hydroxy-1,2-diphenylethylamino)acetate(CAS DataBase Reference)
• NIST Chemistry Reference: Ethyl 2-((1S,2R)-2-hydroxy-1,2-diphenylethylamino)acetate(100678-82-8)
• EPA Substance Registry System: Ethyl 2-((1S,2R)-2-hydroxy-1,2-diphenylethylamino)acetate(100678-82-8)

Safety Data

• Hazardous Substances Data: 100678-82-8(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
Ethyl 2-((1S,2R)-2-hydroxy-1,2-diphenylethylamino)acetate is used as a reactant for the preparation of α-helices of BCL-2 domains, which are crucial in the development of targeted therapies for various diseases, including cancer.
Used in Biochemistry Research:
Ethyl 2-((1S,2R)-2-hydroxy-1,2-diphenylethylamino)acetate is also utilized in the synthesis of collagen cross-linking agents, such as (5S,5’S)-Dihydroxy Lysinonorleucine (D452900), which are essential for studying the structure, function, and stability of collagen proteins in various biological systems.

InChI:InChI=1/C18H21NO3/c1-2-22-16(20)13-19-17(14-9-5-3-6-10-14)18(21)15-11-7-4-8-12-15/h3-12,17-19,21H,2,13H2,1H3

Upstream product

• 23190-16-1 (1R,2S)-2-Amino-1,2-diphenylethanol 
• 105-36-2 ethyl bromoacetate 
• 530-36-9 2-amino-1,2-diphenylethanol 
• 119-53-9 2-hydroxy-2-phenylacetophenone 
• 441-38-3 benzoin oxime 
• 530-36-9 erythro-2-amino-1,2-diphenylethanol 

Downstream Products

• 112741-70-5 (1'S,2'R)-ethyl N-(tert-butyloxycarbonyl)-N-(1',2'-diphenyl-2'-hydroxyethyl)glycinate 
• 100516-60-7 (1'S,2'R)-ethyl N-(benzyloxycarbonyl)-N-(1',2'-diphenyl-2'-hydroxyethyl)glycinate 
• 108865-54-9 Sodium; ((1S,2R)-2-hydroxy-1,2-diphenyl-ethylamino)-acetate 
• 100516-54-9 (5S,6R)-4-(benzyloxycarbonyl)-5,6-diphenyl-2,3,5,6-tetrahydro-4H-1,4-oxazin-2-one 
• 112741-49-8 tert-butyl (2R,3S)-6-oxo-2,3-diphenylmorpholine-4-carboxylate 
• 943-73-7 D-homophenylalanine 
• 100516-58-3 (3S,5S,6R)-4-(benzyloxycarbonyl)-5,6-diphenyl-3-methyl-2,3,5,6-tetrahydro-4H-1,4-oxazin-2-one 
• 100516-55-0 (3S,5S,6R)-4-(benzyloxycarbonyl)-5,6-diphenyl-3-(2'-propenyl)-2,3,5,6-tetrahydro-4H-1,4-oxazin-2-one 
• 100570-94-3 (5S,6R)-3-Bromo-2-oxo-5,6-diphenyl-morpholine-4-carboxylic acid benzyl ester 
• 100516-59-4 (3S,5S,6R)-4-(benzyloxycarbonyl)-3-butyl-5,6-diphenyl-2,3,5,6-tetrahydro-4H-1,4-oxazin-2-one 
• 100516-56-1 (3R,5S,6R)-3-Ethoxycarbonylmethyl-2-oxo-5,6-diphenyl-morpholine-4-carboxylic acid benzyl ester 
• 112741-54-5 (3S,5S,6R)-4-(tert-butyloxycarbonyl)-5,6-diphenyl-3-(1'-prop-2'-enyl)-2,3,5,6-tetrahydro-4H-1,4-oxazin-2-one 
• 112741-51-2 (3S,5S,6R)-3-bromo-4(tert-butoxycarbonyl)-5,6-diphenyl-2,3,5,6-tetrahydro-4H-1,4-oxazin-2-one 
• 112741-67-0 (3S,5S,6R)-4-(benzyloxycarbonyl)-3-(2'-furanyl)-5,6-diphenyl-2,3,5,6-tetrahydro-4H-1,4-oxazin-2-one 

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