10075-61-3

Basic information

• Product Name: Naphthalene, 1,3-dimethoxy-
• Synonyms: Naphthalene, 1,3-dimethoxy-
• CAS NO: 10075-61-3
• Molecular Formula: C₁₂H₁₂O₂
• Molecular Weight: 188.22248
• Mol File: 10075-61-3.mol

Chemical Properties

• Boiling Point: 172-173 °C(Press: 12 Torr)
• Appearance: /
• Density: 1.097±0.06 g/cm3(Predicted)
• CAS DataBase Reference: Naphthalene, 1,3-dimethoxy-(CAS DataBase Reference)
• NIST Chemistry Reference: Naphthalene, 1,3-dimethoxy-(10075-61-3)
• EPA Substance Registry System: Naphthalene, 1,3-dimethoxy-(10075-61-3)

Safety Data

• Hazardous Substances Data: 10075-61-3(Hazardous Substances Data)

Usage

Uses

Used in Organic Synthesis:
Naphthalene, 1,3-dimethoxyis used as a key intermediate in the synthesis of various organic compounds. Its unique structure and reactivity make it a valuable building block for the development of new chemical entities.
Used in Traditional Medicine:
In traditional medicine, Naphthalene, 1,3-dimethoxyhas been employed for its potential therapeutic properties. Its bioactive compounds may contribute to the treatment of certain health conditions, although further research is needed to fully understand its medicinal applications.
Used in Dye Production:
Naphthalene, 1,3-dimethoxyis used as a precursor in the production of dyes. Its chemical structure allows for the creation of a wide range of colors, making it a versatile component in the dye industry.
Used in Pharmaceutical Industry:
Naphthalene, 1,3-dimethoxyis utilized in the pharmaceutical industry for the development of new drugs. Its unique properties and reactivity enable the synthesis of novel pharmaceutical agents with potential therapeutic benefits.
Used in Industrial Applications:
Naphthalene, 1,3-dimethoxyis employed in various industrial applications due to its chemical properties. It serves as a raw material in the production of a range of industrial products, contributing to the development of new technologies and materials.

Upstream product

• 7417-20-1 3,5-dimethoxyphenethyl alcohol 
• 63165-30-0 2-(3,5-dimethoxyphenyl)acetaldehyde 
• 1341189-09-0 C₁₂H₁₄O₃ 
• 132-86-5 1,3-dihydroxynaphthalene 
• 52358-73-3 1,3-dibromonaphthalene 
• 124-41-4 sodium methylate 
• 77-78-1 dimethyl sulfate 
• 186581-53-3 diazomethane 
• 6843-89-6 ethyl 1,3-dihydroxy-2-naphthoate 

Downstream Products

• 75965-84-3 2,4-dimethoxy-1-naphthalenecarbaldehyde 
• 5891-63-4 1-Acetyl-4-methoxy-2-naphthol 
• 60683-60-5 2-Chlor-6-methoxy-4,5-benzotropon 
• 60683-58-1 5-Chlor-6-methoxy-2,3-benzotropon 
• 59115-41-2 1-methoxy-3-phenylnaphthalene 
• 115130-66-0 1,3-dimethoxy-4-(2,3,4,6-tetra-O-benzyl-β-D-glucopyranosyl)naphthalene 

Relevant articles and documents

Selective formation of six-membered oxa- and carbocycles by the In(III)-activated ring closure of acetylenic substrates

Fifteen examples are disclosed of efficient In(III)-catalyzed six-membered ring closure leading to bi-, tri-, and tetracyclic products.

Synthetic route to 1,3-disubstituted naphthalene derivatives

The preparation of methoxy and cyanonaphthalene derivatives is described. The preparation of 1,3-dimethoxynaphthalene, 1-bromo-3-methoxynaphthalene, 1 -methoxy-3-bromonaphthalene and 1,3-dicyanonaphthalene involves the reaction of 1,3-dibromonaphthalene with the corresponding nucleophile.

Electron-deficient nitrogen heterocycle-substituted fluorescein dyes

The invention provides compositions electron-deficient nitrogen heterocycle-substituted fluorescein dyes and methods in which the dyes are conjugated to substrates and used as detection labels in molecular biology experiments. The electron-deficient nitro

Application of a Cu(I)-mediated biaryl cross-coupling reaction to the synthesis of oxygenated 1,1′-binaphthalenes

Application of an oxidative copper(I)-mediated biaryl cross-coupling protocol to the synthesis of highly oxygenated, differentially substituted 1-1′-binaphthalenes related to the perylenequinone calphostin C is detailed.

REACTION OF PHENOLS AND THEIR DERIVATIVES WITH AROMATIC COMPOUNDS IN THE PRESENCE OF ACIDIC AGENTS X. ROTATIONAL ISOMERISM IN THE SERIES OF 2-METHOXY-1-NAPHTHALENONIUM IONS

It was shown by 13C NMR spectroscopy that 4-X-2-methoxy-1-naphthalenonium ions (X=H, Cl, CH3, C6H5), generated in the HSO3F-SO2FCl medium, exist as Z and E isomers due to restricted rotation about the C-O partial double bond.It is not possible to detect Z, E isomerism in the corresponding 4-X-2-hydro-1-naphthalenonium ions or in the 2,4-dimethoxy- and 1-chloro-2-methoxy-1-naphthalenonium ions.

Manganese(III)-Mediated Formylation of Aromatic Compounds in the Presence of Malonic Acid

The reaction of naphthlenes with malonic acid in the presence of manganese(III) acetate gives naphthalenecarbaldehydes and naphthalenecarboxylic acids.Similar reactions of anthracene, pyrene, and methoxybenzenes also yield formylated and carboxylated products.It was found that the formyl group introduced to the aromatic ring was not derived from carboxymethyl radical generated directly by the thermolysis of manganese(III) acetate, but from a dicarboxymethyl radical formed by the interaction of malonic acid and manganese(III) acetate.In addition, it was also found that the dicarboxymethyl radicals attacked the position of the highest electron density on the aromatic ring and that this formylation was effective when the ionization potential of the aromatic copound was lower than 7.8 eV.