- Selective formation of six-membered oxa- and carbocycles by the In(III)-activated ring closure of acetylenic substrates
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Fifteen examples are disclosed of efficient In(III)-catalyzed six-membered ring closure leading to bi-, tri-, and tetracyclic products.
- Qiu, Wen-Wei,Surendra, Karavadhi,Yin, Liang,Corey
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p. 5893 - 5895
(2011/12/16)
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- Synthetic route to 1,3-disubstituted naphthalene derivatives
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The preparation of methoxy and cyanonaphthalene derivatives is described. The preparation of 1,3-dimethoxynaphthalene, 1-bromo-3-methoxynaphthalene, 1 -methoxy-3-bromonaphthalene and 1,3-dicyanonaphthalene involves the reaction of 1,3-dibromonaphthalene with the corresponding nucleophile.
- Demirtas, Ibrahim,Erenler, Ramazan,Cakmak, Osman
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p. 524 - 526
(2007/10/03)
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- Electron-deficient nitrogen heterocycle-substituted fluorescein dyes
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The invention provides compositions electron-deficient nitrogen heterocycle-substituted fluorescein dyes and methods in which the dyes are conjugated to substrates and used as detection labels in molecular biology experiments. The electron-deficient nitro
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- Application of a Cu(I)-mediated biaryl cross-coupling reaction to the synthesis of oxygenated 1,1′-binaphthalenes
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Application of an oxidative copper(I)-mediated biaryl cross-coupling protocol to the synthesis of highly oxygenated, differentially substituted 1-1′-binaphthalenes related to the perylenequinone calphostin C is detailed.
- Coleman, Robert S.,Grant, Eugene B.
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p. 2225 - 2228
(2007/10/02)
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- REACTION OF PHENOLS AND THEIR DERIVATIVES WITH AROMATIC COMPOUNDS IN THE PRESENCE OF ACIDIC AGENTS X. ROTATIONAL ISOMERISM IN THE SERIES OF 2-METHOXY-1-NAPHTHALENONIUM IONS
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It was shown by 13C NMR spectroscopy that 4-X-2-methoxy-1-naphthalenonium ions (X=H, Cl, CH3, C6H5), generated in the HSO3F-SO2FCl medium, exist as Z and E isomers due to restricted rotation about the C-O partial double bond.It is not possible to detect Z, E isomerism in the corresponding 4-X-2-hydro-1-naphthalenonium ions or in the 2,4-dimethoxy- and 1-chloro-2-methoxy-1-naphthalenonium ions.
- Repinskaya, I. B.,Shakirov, M. M.,Koltunov, K. Yu.,Koptyug, V. A.
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p. 778 - 784
(2007/10/02)
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- Manganese(III)-Mediated Formylation of Aromatic Compounds in the Presence of Malonic Acid
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The reaction of naphthlenes with malonic acid in the presence of manganese(III) acetate gives naphthalenecarbaldehydes and naphthalenecarboxylic acids.Similar reactions of anthracene, pyrene, and methoxybenzenes also yield formylated and carboxylated products.It was found that the formyl group introduced to the aromatic ring was not derived from carboxymethyl radical generated directly by the thermolysis of manganese(III) acetate, but from a dicarboxymethyl radical formed by the interaction of malonic acid and manganese(III) acetate.In addition, it was also found that the dicarboxymethyl radicals attacked the position of the highest electron density on the aromatic ring and that this formylation was effective when the ionization potential of the aromatic copound was lower than 7.8 eV.
- Nishino, Hiroshi,Tsunoda, Katsunori,Kurosawa, Kazu
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p. 545 - 550
(2007/10/02)
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