10124-48-8

Basic information

• Product Name: Aminomercuric chloride
• Synonyms: aminomercurychloride;ammoniated;ammoniatedmercuricchloride;hydrargyrumammoniatum;hydrargyrumprecipitatumalbum;mercuricamidochloride;mercury(ii)chlorideammonobasic;mercury,ammonobasic(hgnh2cl)
• CAS NO: 10124-48-8
• Molecular Formula: Cl*H₂N*Hg
• Molecular Weight: 252.07
• EINECS: 233-335-8
• Mol File: 10124-48-8.mol

Chemical Properties

• Melting Point: 383°C (dec.)
• Boiling Point: sublimes [CRC10]
• Appearance: /white solid
• Density: 5.38
• Water Solubility: insoluble H2O, EtOH; soluble warm acid [CRC10]
• Stability: Stable.
• Merck: 13,5902
• CAS DataBase Reference: Aminomercuric chloride(CAS DataBase Reference)
• NIST Chemistry Reference: Aminomercuric chloride(10124-48-8)
• EPA Substance Registry System: Aminomercuric chloride(10124-48-8)

Safety Data

• Hazard Codes: T+;N,N,T+
• Statements: 26/27/28-33-50/53
• Safety Statements: 13-28-45-60-61
• RIDADR: 2025
• WGK Germany: 3
• RTECS: OV7020000
• HazardClass: 6.1(a)
• PackingGroup: II
• Hazardous Substances Data: 10124-48-8(Hazardous Substances Data)

Usage

Chemical Properties

white powder

Uses

Different sources of media describe the Uses of 10124-48-8 differently. You can refer to the following data:
1. Anti-infective, topical.
2. Mercury ammonium chloride is an inorganic mercurial compound used in creams as a topical anti-infective agent (formerly used in the treatment of psoriasis and in skin-lightening formulations).

General Description

A white crystalline solid. Corrosive to the mucous membranes. Very toxic by inhalation and ingestion.

Air & Water Reactions

Slightly water soluble. Decomposes in hot water.

Reactivity Profile

Aminomercuric chloride is incompatible with acetylene, ammonia, chlorine dioxide, azides, calcium (amalgam formation), sodium carbide, lithium, rubidium, copper .

Health Hazard

The general symptoms are those of mercury poisoning, developing rapidly after ingestion but more slowly after low repeated exposures. Contact with eyes causes irritation and ulceration. Skin contact may cause dermatitis. Ingestion causes pain, vomiting, metallic taste, ulceration of mouth and stomach, pallor, and rapid, weak pulse.

Fire Hazard

Special Hazards of Combustion Products: Smoke may contain toxic mercury compounds.

Safety Profile

A poison by ingestion. Moderately toxic by skin contact. Explosive reaction with halogens or amine metal salts. When heated to decomposition it emits very toxic fumes of Cl-, NOx, and Hg. See also MERCURY COMPOUNDS.

InChI:InChI=1/ClH.Hg.H3N/h1H;;1H3/q;+2;

Synthetic route

ammonium chloride + ammonia (7664-41-7) → Hg(NH2)Cl (10124-48-8) + mercury(II) diammonium chloride + Hg2N(1+)*Cl(1-)*H2O=Hg2NCl*H2O

Conditions	Yield
With HgCl2 In water dissolving mixt. of NH4Cl and HgCl2 in H2O, then in 8 % NH3 soln., shaking 6 days at ambient temp.; quality of products depending on ratio of educts and solvents;

diammonium hydrogenphosphate → Hg(NH2)Cl (10124-48-8)

Conditions	Yield
With mercury dichloride In not given
With HgCl2 In not given

ammonia (7664-41-7) → Hg(NH2)Cl (10124-48-8)

Conditions	Yield
With mercury dichloride In ammonia byproducts: NH4Cl;
With HgCl2 In ammonia byproducts: NH4Cl; NH3 (liquid);

ammonia (7664-41-7) + mercury dichloride → Hg(NH2)Cl (10124-48-8) + ammonium chloride

Conditions	Yield
In water calcd. amts. of educts; washing with H2O, drying 110°C;
In water calcd. amts. of educts; washing with H2O, drying 110°C;

ammonia (7664-41-7) + mercury dichloride → Hg(NH2)Cl (10124-48-8) + mercury(II) diammonium chloride

Conditions	Yield
With KCL In water in presence of KCl, quality of products depending on ratio of educts and KCl;

ammonia (7664-41-7) + mercury dichloride → Hg(NH2)Cl (10124-48-8) + Hg2N(1+)*Cl(1-)*H2O=Hg2NCl*H2O

Conditions	Yield
In water with calcd. amts. of educts;
In water 0.032n HgCl2 reacted with NH3 soln. (various concentration), ratio of products depending on concentration of NH3 soln. and on ratio of eduts;
In water with calcd. amts. of educts;

ammonia (7664-41-7) + mercury dichloride → Hg(NH2)Cl (10124-48-8) + Hg2N(1+)*Cl(1-)=Hg2NCl

Conditions	Yield
With potassium hydroxide In water in presence of KOH;
With KOH In water in presence of KOH;

ammonia (7664-41-7) + mercury dichloride → Hg(NH2)Cl (10124-48-8) + 2Hg2N(1+)*2Cl(1-)*HgCl2=(Hg2NCl)2*HgCl2

Conditions	Yield
In water excess of HgCl2, ambient temp.;

mercury(I) oxide + ammonium chloride → Hg(NH2)Cl (10124-48-8) + water (7732-18-5) + mercury

Conditions	Yield
In water in presence of NH3;

Hg(2+)*2NH3*2Cl(1-)=Hg(NH3)2Cl2 + water (7732-18-5) → Hg(NH2)Cl (10124-48-8)

Conditions	Yield
careful treatment;

mercury(I) chloride → Hg(NH2)Cl (10124-48-8) + mercury(II) diammonium chloride + ammonium chloride + mercury

Conditions	Yield
With ammonia In water Cl2 decompd. and formed HgNH2Cl;
With NH3 In water Cl2 decompd. and formed HgNH2Cl;

mercury(I) chloride → Hg(NH2)Cl (10124-48-8) + mercury(II) diammonium chloride + Hg2N(1+)*Cl(1-)*H2O=Hg2NCl*H2O + mercury

Conditions	Yield
With NH3 In water

ammonium hydroxide + mercury(I) chloride → Hg(NH2)Cl (10124-48-8) + ammonium chloride + water (7732-18-5) + mercury

Conditions	Yield
In water boiling;
In water 0.1 m NH3 soln., 48 h;

ammonium hydroxide + mercury(I) chloride → mercury(I) oxide + Hg(NH2)Cl (10124-48-8) + ammonium chloride + water (7732-18-5) + mercury

Conditions	Yield
In water

ammonia (7664-41-7) + mercury dichloride → Hg(NH2)Cl (10124-48-8) + Hg(2+)*2NH3*2Cl(1-)=Hg(NH3)2Cl2 + ammonium chloride

Conditions	Yield
In nitric acid aq. HNO3; adding aq. NH3 soln. to HgCl2 soln.; increasing of formation of Hg(NH3)2Cl2 depends on NH4(1+) concn.;
In nitric acid

ammonia (7664-41-7) + mercury dichloride → Hg(NH2)Cl (10124-48-8)

Conditions	Yield
In water HgCl2 dissolved in water, 10% aq. NH3 added; ppt. washed with cold water;

Hg2N(1+)*Cl(1-)*H2O=Hg2NCl*H2O + ammonium chloride → Hg(NH2)Cl (10124-48-8)

Conditions	Yield
In water
In water

Hg2NH2Cl → Hg(NH2)Cl (10124-48-8) + mercury

Conditions	Yield
In water equil. reaction;
slow disproportionation; equilibrium reaction;
In water equil. reaction;

mercury(II) diammonium chloride → Hg(NH2)Cl (10124-48-8) + ammonium chloride

Conditions	Yield
With H2O In water ambient temp, 30 h;
With NH3; H2O In water shaking, 20-22°C, addn. of NH3 soln.; washing with alc. and ether;
In water equil. reaction.;
In water equil. reaction;

mercury(II) diammonium chloride → Hg(NH2)Cl (10124-48-8)

Conditions	Yield
With water In water equil. reaction, 15-30°C;
With H2O In water equil. reaction, 15-30°C;
In water

mercury(II) diammonium chloride → Hg(NH2)Cl (10124-48-8) + HgCl(OH)NH3 + {Hg(NH3)2}(2+)*2Cl(1-)*HgO={Hg(NH3)2}Cl2*HgO + {Hg(NH3)2}(2+)*2Cl(1-)*2HgNH2Cl={Hg(NH3)2}Cl2*2HgNH2Cl

Conditions	Yield
With OH(1-) In water in abscence of NH4Cl;

mercury(II) diammonium chloride → Hg(NH2)Cl (10124-48-8) + Hg2N(1+)*Cl(1-)*H2O=Hg2NCl*H2O

Conditions	Yield
With ammonia In water ratio of products depending on quantity of NH3 soln. (D=0.923), shaking 1 month;
With NH3 In water ratio of products depending on quantity of NH3 soln. (D=0.923), shaking 1 month;

antipyrine (60-80-0) + Hg(NH2)Cl (10124-48-8) → 1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-ylmercury (1+); chloride-monohydrate

Conditions	Yield
In water The mixt. of reagents in water was refluxed for 20 min;; fitered, concd., ppt. was filtered, crystd. from water ; elem. anal.;;	30%

Hg(NH2)Cl (10124-48-8) + ammonium chloride → HgNH2Cl*HgCl2

Conditions	Yield
With mercury dichloride In water addn. of concd. HgCl2 soln. (contained aq. NH4Cl soln.) to HgNH2Cl at different temp.;
With HgCl2 In water addn. of concd. HgCl2 soln. (contained aq. NH4Cl soln.) to HgNH2Cl at different temp.;
With HgCl2 In water shaking of HgNH2Cl with concd. HgCl2 soln. (contained 0.5 % NH4Cl);

Hg(NH2)Cl (10124-48-8) + ammonium chloride → mercury(II) diammonium chloride

Conditions	Yield
In water ambient temp., or with excess of 10 % NH4Cl soln.;

potassium chromate + Hg(NH2)Cl (10124-48-8) → 2{Hg2N}(1+)*CrO4(2-)*2H2O={Hg2N}2CrO4*2H2O

Conditions	Yield
In not given byproducts: NH3; freshly prepared Hg(NH2)Cl and concd. K2CrO4 soln. are heated on a water-bath or the mixt. is stirred for 12h;; filtration; washing; drying in vac. over H2SO4;;

potassium chromate + Hg(NH2)Cl (10124-48-8) → 4Hg(2+)*2O(2-)*2NH2(1-)*CrO4(2-)={OHg2NH2}2CrO4

Conditions	Yield
In not given treating H2NHgCl with K2CrO4 soln.;;

Hg(NH2)Cl (10124-48-8) → Hg2N(1+)*Cl(1-)*H2O=Hg2NCl*H2O + ammonium chloride

Conditions	Yield
With water In water equil. reaction;
With H2O In water equil. reaction;

Hg(NH2)Cl (10124-48-8) → Hg2N(1+)*Cl(1-)=Hg2NCl + ammonium chloride

Conditions	Yield
In water equil. reaction,;
In water equil. reaction;

Hg(NH2)Cl (10124-48-8) → Hg(OH)Cl (13759-23-4) + ammonia (7664-41-7)

Conditions	Yield
With H2O In water equil. reaction;

Hg(NH2)Cl (10124-48-8) → mercury(II) diammonium chloride + 3HgCl2*2NH3

Conditions	Yield
With HgCl2 In water quality of products depending on ratio of educts;

Hg(NH2)Cl (10124-48-8) → mercury(II) diammonium chloride

Conditions	Yield
With ammonia In water
With NH3 In water

Hg(NH2)Cl (10124-48-8) → mercury(II) diammonium chloride + 3Hg(2+)*2NH4(1+)*8Cl(1-)=3HgCl2*2NH4Cl

Conditions	Yield
With mercury dichloride In water quality of products depending on ratio of educts;
With HgCl2 In water quality of products depending on ratio of educts;

Hg(NH2)Cl (10124-48-8) → 2{Hg(NH3)2}(2+)*4Cl(1-)*HgO*H2O=2{Hg(NH3)2}Cl2*HgO*H2O

Conditions	Yield
With H2O In water 20-22°C;

Hg(NH2)Cl (10124-48-8) → Hg2N(1+)*Cl(1-)*H2O=Hg2NCl*H2O

Conditions	Yield
With ammonia In water dildn. NH3 soln.;
With H2O In water 15-30°C;
With NH3 In water dildn. NH3 soln.;

Hg(NH2)Cl (10124-48-8) → Hg2N(1+)*Cl(1-)=Hg2NCl

Conditions	Yield
With NaOH In hydrogenchloride addn. of sol. of HgNH2Cl in hot 25 % HCl soln. to 1n NaOH soln., standing 1 day;
In water

Hg(NH2)Cl (10124-48-8) → HgNH2Cl*HgCl2

Conditions	Yield
With HgCl2
With HgCl2

Hg(NH2)Cl (10124-48-8) → NH4(1+)*{Hg(Cl)(SO3)}(1-)=NH4{Hg(Cl)(SO3)}

Conditions	Yield
With sulfur dioxide In water
With SO2 In water

Hg(NH2)Cl (10124-48-8) → ammonia (7664-41-7) + mercury dichloride

Conditions	Yield
With H2O In water with boiling water;

Hg(NH2)Cl (10124-48-8) + platinum(IV) chloride (13454-96-1) → HgNH2Cl*PtCl4

Conditions	Yield
In ammonia in concd. aq. NH3 soln.;
In ammonia aq. ammonia=NH3; in concd. aq. NH3 soln.;

Hg(NH2)Cl (10124-48-8) + platinum(IV) chloride (13454-96-1) → mercury(II) platinum(IV) amidochloride

Conditions	Yield
With ammonia In water dried above H2SO4;

Hg(NH2)Cl (10124-48-8) + ammonium hydroxide → HgNH2OH + ammonium chloride

Conditions	Yield
In water

Upstream product

• 7664-41-7 ammonia 
• 7732-18-5 water 
• 104923-33-3 mercury(I) chloride 

Downstream Products

• 940-71-6 2,2,4,4,6,6-hexachloro-1,3,5-triaza-2,4,6-triphosphorine 
• 7647-01-0 hydrogenchloride 
• 13759-23-4 Hg(OH)Cl 
• 7664-41-7 ammonia 

Relevant articles and documents

Crystal growth and refinement of the crystal structure of mercury(II) amide chloride - HgClNH2

Single crystals were prepared by recrystallization of HgClNH2 from aqueous NH3/NH4+ solution at 160 °C. They were used for a single-crystal X-ray structure redetermination. The previously reported [W. N. Lipscomb, Acta. Crystallogr. 1951, 4, 266.] structural topology determined on basis of X-ray powder diffraction data is now confirmed. However, a higher symmetry is found: Space group type Pmma (instead of Pmrn2), a = 6.709(1) A?, b = 4.351(1) A?, c = 5.154(1) A?, Z = 2. The crystal structure contains zig-zag-chains 1∞[Hg(NH2)2/2]+. Four Cl atoms complete the coordination sphere of Hg to a distorted octahedron. These share common faces and edges in layers 2∞[HgCl4/4(NH2) 2/2]. These layers are connected via hydrogen bonds N-H ? Cl.

Two mercuric ammoniates: [Hg(NH3)2][HgCl3]2 and [Hg(NH3)4](ClO4)2

[Hg(NH3)2][HgCl3]2 (1) is obtained by saturating an equimolar solution of HgCl2 and NH4Cl with Hg(NH2)Cl at 75 °C. 1 crystallizes in the orthorhombic space group Pmna with a = 591.9(1) pm, b = 800.3(1) pm, c = 1243.3(4) pm, Z = 2. The structure consists of linear cations [Hg(NH3)2]2+ and T-shaped anions [HgCl3]-. The coordination sphere of mercury is effectively completed to compressed hexagonal bipyramids and distorted octahedra, respectively. Single crystals of [Hg(NH3)4](ClO4)2 (2) are obtained by passing gaseous ammonia through a solution of mercuric perchlorate, while the solution was cooled to temperatures below 10 °C. 2 crystallizes in the monoclinic space group P21/c with a = 791.52(9) pm, b = 1084.3(2) pm, c = 1566.4(2)pm, β = 120.352(1)°, Z = 4. The structure consists of compressed [Hg(NH3)4]2+ tetrahedra and perchlorate anions. The packing of the heavy atoms Hg and Cl is analogous to the baddeleyite (α-ZrO2) type of structure.