13454-96-1

Basic information

• Product Name: Platinum tetrachloride
• Synonyms: PLATINIC CHLORIDE;PLATINUM TETRACHLORIDE;PLATINUM CHLORIDE;PLATINUM(IV) CHLORIDE;(SP-4-1)-Platinumchloride;(sp-4-1)-platinumchloride(ptcl4;platinum(iv)tetrachloride;platinumchloride(ptcl4)
• CAS NO: 13454-96-1
• Molecular Formula: Cl₄Pt
• Molecular Weight: 336.89
• EINECS: 236-645-1
• Product Categories: Inorganics;metal halide;chemical reaction,pharm,electronic,materials
• Mol File: 13454-96-1.mol
• Article Data: 6

Chemical Properties

• Melting Point: 370 °C (dec.)(lit.)
• Appearance: Red-brown/Powder
• Density: 4.303 g/mL at 25 °C(lit.)
• Storage Temp.: Store below +30°C.
• Solubility: 587g/l
• Water Solubility: 587 g/L (25 ºC)
• Sensitive: Hygroscopic
• CAS DataBase Reference: Platinum tetrachloride(CAS DataBase Reference)
• NIST Chemistry Reference: Platinum tetrachloride(13454-96-1)
• EPA Substance Registry System: Platinum tetrachloride(13454-96-1)

Safety Data

• Hazard Codes: C
• Statements: 22-34-42/43
• Safety Statements: 26-27-36/37/39-45-24-22
• RIDADR: UN 2923 8/PG 3
• WGK Germany: 3
• RTECS: TP2275500
• F: 21
• TSCA: Yes
• HazardClass: 8
• PackingGroup: III
• Hazardous Substances Data: 13454-96-1(Hazardous Substances Data)

Usage

Chemical Properties

Brown/Red Crystals

Uses

Platinum(IV) chloride is used as a catalyst and analytical reagent. Further, it is used in the production of semiconductor epitaxy and in electroplating process. It is involved in the preparation of platinum(II) chloride .

Production Methods

PtCl4 is formed directly from the elements or by heating hexachloroplatinic (IV) acid.

Safety Profile

Poison by ingestion and intravenous routes. Experimental reproductive effects. Mutation data reported. A severe skin irritant. When heated to decomposition it emits toxic fumes of Cl-. See also PLATINUM COMPOUNDS.

InChI:InChI=1/4ClH.2Pt/h4*1H;;/q;;;;2*+2/p-4

Synthetic route

sulfuryl dichloride (7791-25-5) + platinum (7440-06-4) → platinum(IV) chloride (13454-96-1)

Conditions	Yield
In neat (no solvent) heating for some days to 150°C;;
In neat (no solvent) some days (150°C); platinum wire;;
In neat (no solvent) heating for some days to 150°C;;

hydrogenchloride (7647-01-0) + platinum (7440-06-4) → platinum(IV) chloride (13454-96-1)

Conditions	Yield
With tris-(2-chloro-ethyl)-amine In not given byproducts: NH3, N2; Pt is dissolved in a mixture of HCl and HN3;;
With HN3 In not given byproducts: NH3, N2; Pt is dissolved in a mixture of HCl and HN3;;

chlorine (7782-50-5) + platinum (7440-06-4) → platinum(IV) chloride (13454-96-1)

Conditions	Yield
In neat (no solvent) at 1700°C;;
In neat (no solvent) High Pressure; Pt metal reacted with Cl2 under pressure 50 atm in thick-wall quartz tube at 200°C for 5 d; XRD, IR, elem. anal.;
In neat (no solvent) at 1700°C;;

chlorine (7782-50-5) + platinum (7440-06-4) → platinum trichloride (25909-39-1) + platinum(IV) chloride (13454-96-1)

Conditions	Yield
In neat (no solvent) platinum black is heated in a Cl2 stream to 360°C, fast cooling;;
In neat (no solvent) platinum black is heated in a Cl2 stream to 360°C, fast cooling;;

potassium tetrachloroplatinate(II) (10025-99-7) → platinum(IV) chloride (13454-96-1)

Conditions	Yield
With CoW12O40(5-) In water Kinetics; byproducts: CoW12O40(6-); oxidation of Pt(II) by Co(III)W12O40(5-) in H2O at 25.0°C; mechanism discussed; not isolated, detected by UV spectroscopy;

platinum tetraiodide (7790-46-7) → dihydrogen hexachloroplatinate + iodine (7553-56-2) + Iodine monochloride (7790-99-0) + platinum(IV) chloride (13454-96-1)

Conditions	Yield
With chlorine In water composition of product depends on amount of Cl2;
With Cl2 In water composition of product depends on amount of Cl2;

platinum tetraiodide (7790-46-7) → Iodine monochloride (7790-99-0) + platinum(IV) chloride (13454-96-1)

Conditions	Yield
With chlorine in cold Cl2 flow;
With Cl2 in cold Cl2 flow;

platinum(IV) chloride pentahydrate → platinum(IV) chloride (13454-96-1)

Conditions	Yield
byproducts: H2O; heating in vacuum at 215°C over KOH;
at 215°C in vacuum over KOH;
byproducts: H2O; heating in vacuum at 215°C over KOH;
at 215°C in vacuum over KOH;

platinum diselenide → platinum(IV) chloride (13454-96-1)

Conditions	Yield
With chlorine in Cl2 flow at 300°C;	0%
With Cl2 in Cl2 flow at 300°C;	0%

platinum diselenide + arsenic trichloride (7784-34-1) → platinum(IV) chloride (13454-96-1)

Conditions	Yield
at 300°C;	0%
at 300°C;	0%

PtCl2I2 (15619-71-3) + Iodine monochloride (7790-99-0) → iodine (7553-56-2) + platinum(IV) chloride (13454-96-1)

β-platinum(II) chloride → platinum(IV) chloride (13454-96-1)

Conditions	Yield
In neat (no solvent) heating (270 or 350°C, 24 h);

barium platinum(IV) chloride (164793-21-9) → platinum(IV) chloride (13454-96-1) + platinum (7440-06-4) + barium(II) chloride

Conditions	Yield
byproducts: Cl2; glow;
byproducts: Cl2; glow;

barium platinum(IV) chloride*6H2O → platinum(IV) chloride (13454-96-1) + barium(II) chloride

Conditions	Yield
With water
With ethanol boiling;
With methanol

magnesium platinum(IV) chloride*6H2O → platinum(IV) chloride (13454-96-1)

Conditions	Yield
In methanol byproducts: MgCl2;
In ethanol byproducts: MgCl2;
In methanol byproducts: MgCl2;
In ethanol byproducts: MgCl2;

calcium platinum(IV) chloride*8H2O → platinum(IV) chloride (13454-96-1)

Conditions	Yield
With ethanol byproducts: CaCl2;
With methanol byproducts: CaCl2;
With ethanol byproducts: CaCl2;
With methanol byproducts: CaCl2;

lead(II) platinum(IV) chloride*3H2O → platinum(IV) chloride (13454-96-1) + lead(II) chloride

Conditions	Yield
In water partial decompn. in H2O soln.;
With ethanol
In water partial decompn. in H2O soln.;
With ethanol

arsenic trichloride (7784-34-1) + platinum (7440-06-4) → platinum(IV) chloride (13454-96-1)

Conditions	Yield
in a sealed tube;
in a sealed tube;

selenium (7782-49-2) + arsenic trichloride (7784-34-1) + platinum (7440-06-4) → platinum(IV) chloride (13454-96-1)

Conditions	Yield
With chlorine heating in Cl2 flow for 0.5 h, then in a sealed tube at 250°C for more h; after selection of AsCl3 heating 1 h at 360°C in Cl2 flow; at 100°C in vacuum from AsCl3; at 200°C from SeCl4;
With Cl2 heating in Cl2 flow for 0.5 h, then in a sealed tube at 250°C for more h; after selection of AsCl3 heating 1 h at 360°C in Cl2 flow; at 100°C in vacuum from AsCl3; at 200°C from SeCl4;

ammonium hexachloroplatinate → platinum(IV) chloride (13454-96-1)

Conditions	Yield
With chlorine In neat (no solvent) byproducts: HCl, N2; loss of 12.23 wt.-% on heating at 360°C in stream of Cl2 for 5 hours;;
With Cl2 In neat (no solvent) byproducts: HCl, N2; loss of 12.23 wt.-% on heating at 360°C in stream of Cl2 for 5 hours;;

potassium hexachloropalatinate(IV) → platinum(IV) chloride (13454-96-1)

Conditions	Yield
platinum In water byproducts: HCl; hydrolysis; establishment of equil. in darkness: 0.01-0.005 M aq. K2(PtCl6) soln. at 20°C within 200 days, no remarkable decompn. of 0.0025 M or more diluted soln. within 0.5 years; catalyst: Pt black; autocatalysis by hydrolysis product;;
In water byproducts: HCl; Irradiation (UV/VIS); hydrolysis, equil. reaction; establishment of equil. of 0.0025 M ore more diluted aq. K2(PtCl6) soln. within 2 days; reaction rate depends on intensity of light and autocatalysis of hydrolysis product;;
platinum In water byproducts: HCl; hydrolysis; establishment of equil. in darkness: 0.01-0.005 M aq. K2(PtCl6) soln. at 20°C within 200 days, no remarkable decompn. of 0.0025 M or more diluted soln. within 0.5 years; catalyst: Pt black; autocatalysis by hydrolysis product;;
In water byproducts: HCl; Irradiation (UV/VIS); hydrolysis, equil. reaction; establishment of equil. of 0.0025 M ore more diluted aq. K2(PtCl6) soln. within 2 days; reaction rate depends on intensity of light and autocatalysis of hydrolysis product;;

dihydrogen hexachloroplatinate → platinum(IV) chloride (13454-96-1)

Conditions	Yield
With H2SO4 In not given in concd. soln.;
With sulfuric acid In not given in concd. soln.;

selenium tetrachloride (10026-03-6) + platinum (7440-06-4) → platinum(IV) chloride (13454-96-1)

dihydrogen hexachloroplatinate(IV) hexahydrate → platinum(IV) chloride (13454-96-1)

Conditions	Yield
With potassium hydroxide; chlorine byproducts: H2O; drying in vacuum over KOH for more d; then heating for 5 h in vacuum at 170°C over KOH;
at higher temp.;
decompn. at 110°C;

dihydrogen hexachloroplatinate(IV) hexahydrate → platinum(IV) chloride (13454-96-1) + platinum (7440-06-4)

Conditions	Yield
at 150°C for 24 h; formation of PtCl2is poor;
at 150°C for 24 h; formation of PtCl2is poor;

dihydrogen hexachloroplatinate(IV) hexahydrate → platinum(IV) chloride (13454-96-1) + platinum(II) chloride

Conditions	Yield
heating in dry air at 200°C for 4.5 h;
With hydrogenchloride in HCl flow, between 170 and 200°C; at 165°C only PtCl4 formed;
With HCl in HCl flow, between 170 and 200°C; at 165°C only PtCl4 formed;
heating in dry air at 200°C for 4.5 h;

dihydrogen hexachloroplatinate(IV) hexahydrate + chlorine (7782-50-5) → platinum(IV) chloride (13454-96-1)

Conditions	Yield
In neat (no solvent, solid phase) Pt compd. heated in corundum crucible in a quartz tube under Cl2 stream up to 513 K for 2-3 h;
In neat (no solvent, solid phase) H2PtCl6*6H2O in chlorine decomposed at 493 K for 8-10 h according to G. Brauer, Handbuch der Preparativen Anorganischen Chemie, Ferdinand Enke Verlag, Stuttgart, 1956; elem. anal.;

sodium hexachloroplatinate → platinum(IV) chloride (13454-96-1)

Conditions	Yield
In ethanol byproducts: NaCl; partial decompn. of Na2(PtCl6) on boiling ethanolic soln. by presence of ether;;
In ethanol byproducts: NaCl; decompn. on boiling in ethanol;;
In ethanol byproducts: NaCl; partial decompn. of Na2(PtCl6) on boiling ethanolic soln. by presence of ether;;
In ethanol byproducts: NaCl; decompn. on boiling in ethanol;;

platinum trichloride (25909-39-1) → platinum(IV) chloride (13454-96-1)

Conditions	Yield
With chlorine in Cl2 (1 atm) at 364°C it is an equilibrium;
With Cl2 in Cl2 (1 atm) at 364°C it is an equilibrium;

platinum(IV) chloride (13454-96-1) + magnesium (7439-95-4) → platinum (7440-06-4)

Conditions	Yield
In water reduction with Mg in neutral or acidic soln.;	100%
In water reduction with Mg in neutral or acidic soln.;	100%
In water reaction in neutral and acid solutions complete;;

closo-1-Sn-2-(SiMe3)-3-(SiMe3)-2,3-C2B4H4 (90388-43-5) + platinum(IV) chloride (13454-96-1) → 1,2-bis(trimethylsilyl)-1,2-dicarba-closo-hexaborane(6) (150378-21-5)

Conditions	Yield
In benzene byproducts: SnCl2, Pt; Sn-compd. soln. poured in react. flask with PtCl4 (vac., -23°C); warming (room temp.); monitoring by (11)B-NMR; volatiles fractionation, trap at -45°C collection of B-compd.; elem. anal.; residue in react. flask dissoln. (THF), soln. filtration, THF removal from filtrate, residue drying (80°C, vac.) gave solid SnCl2;	98%
In hexane Sn-compd. soln. poured in react. flask with PtCl4 (vac., -23°C); warming (room temp.); monitoring by (11)B-NMR; volatiles fractionation, trap at -45°C collection of B-compd.; elem. anal.; residue in react. flask dissoln. (THF), soln. filtration, THF removal from filtrate, residue drying (80°C, vac.) gave solid SnCl2;	98%
In chloroform byproducts: SnCl2, Pt; Sn-compd. soln. poured in react. flask with PtCl4 (vac., -23°C); warming (room temp.); monitoring by (11)B-NMR; volatiles fractionation, trap at -45°C collection of B-compd.; elem. anal.; residue in react. flask dissoln. (THF), soln. filtration, THF removal from filtrate, residue drying (80°C, vac.) gave solid SnCl2;	98%

1-n-butyl-4-methylpyridinium chloride (112400-86-9) + platinum(IV) chloride (13454-96-1) → bis(1-butyl-4-methylpyridinium) hexachloroplatinate(IV)

Conditions	Yield
In acetonitrile for 3h; Schlenk technique; Reflux;	98%

platinum(IV) chloride (13454-96-1) + 3-butyl-1,2-dimethylimidazolium chloride → bis(1-butyl-2,3-dimethylimidazolium) hexachloroplatinate(IV)

Conditions	Yield
In acetonitrile for 3h; Schlenk technique; Reflux;	96%

platinum(IV) chloride (13454-96-1) + 1-butyl-3-methylimidazolium chloride (79917-90-1) → bis(1-n-buthyl-3-methylimidazolium) hexachloroplatinate(IV)

Conditions	Yield
In acetonitrile for 3h; Schlenk technique; Reflux;	95%

platinum(IV) chloride (13454-96-1) + Piroxicam (36322-90-4) → C30H24Cl2N6O8PtS2

Conditions	Yield
Stage #1: Piroxicam With sodium hydroxide In ethanol Stage #2: platinum(IV) chloride In ethanol for 3h; Reflux;	95%

8-quinolinol (148-24-3) + platinum(IV) chloride (13454-96-1) → [Pt(8-hydroxyquinoline)2Cl2]2Cl*2H2O

Conditions	Yield
pH=2;	90%

bis(dimethylamine)chlor(methyl)boronium chloride (92348-89-5) + platinum(IV) chloride (13454-96-1) → 2((CH3)2NH)2BCl(CH3)(1+)*PtCl6(2-)={((CH3)2NH)2BCl(CH3)}2{PtCl6}

Conditions	Yield
With hydrogenchloride In diethyl ether	89.3%
With HCl In diethyl ether	89.3%

4-hydroxy-N’-((5-nitrofuran-2-yl)methylene)benzohydrazide (965-52-6) + water (7732-18-5) + platinum(IV) chloride (13454-96-1) → [Pt(nifuroxazide)2Cl2]Cl2·2H2O

Conditions	Yield
Stage #1: 4-hydroxy-N’-((5-nitrofuran-2-yl)methylene)benzohydrazide; platinum(IV) chloride In methanol at 20℃; for 24h; Stage #2: water	88%

platinum(IV) chloride (13454-96-1) + 2-cyano-2-(p-tolylhydrazono)thioacetamide (112853-36-8) → [Pt(2-cyano-2-(p-tolylhydrazono)thioacetamide)2Cl2]Cl2*4H2O

Conditions	Yield
In acetone at 20℃; for 24h;	87.67%

bis(tetrabutylammonium) hexachloroplatinate(IV) + platinum(IV) chloride (13454-96-1) → [tetrabutylammonium]2[Pt2Cl10]

Conditions	Yield
In thionyl chloride (N2); stirred at room temp. for 12 h; evapd., treated with toluene, filtered, dried (vac.); elem. anal.;	83%

2-methoxy-6-((2-(4-(trifluoromethyl) pyrimidin-2-yl)hydrazono)methyl)phenol + platinum(IV) chloride (13454-96-1) → C26H20Cl2F6N8O4Pt

Conditions	Yield
In ethanol; acetone for 2h;	82%

Homophthalic acid (89-51-0) + platinum(IV) chloride (13454-96-1) + 1,10-phenanthroline hydrate (5144-89-8) → 1,10-phenanthroline platinum(IV) homophthalate (139940-18-4)

Conditions

Yield

With KOH In water byproducts: HCl; soln. of PtCl4 in distd. H2O was mixed homogeneously with soln. of homophthalic acid in ethanol and refluxed for 1h, pH raised to 6.0 by addn. of ethanolic KOH, soln. of 1,10-phenanthroline in ethanol was added, heated at 70 °C for 1h, cooled;; formed ppt. was filtered, washed several times successively with distd. H2O and ethanol, dried in a vacuum desiccator over silica gel; elem. anal.;;

81%

chromonethiobarbituric acid (263146-62-9) + water (7732-18-5) + platinum(IV) chloride (13454-96-1) → [Pt(C15H9N2O6S)2(H2O)2](2+)*2Cl(1-)*3H2O=[Pt(C15H9N2O6S)2(H2O)2]Cl2*3H2O

Conditions

Yield

With ammonium hydroxide In 1,4-dioxane; water byproducts: HCl; the complex was prepd. by mixing a hot aq. soln. of the metal chloride (2.5 mmol) with hot dioxane soln. of the ligand (5 mmol); the react. mixt. was then refluxed; aq. ammonia soln. (1:10) was slowly added with stirring (pH 5.0-5.5); the ppt. was filtered, washed with hot dioxane and diethyl ether and dried over anhyd. CaCl2; elem. anal.;

80%

1-ethyl-3-methylimidazolium tetrachloroaluminate(III) + platinum(IV) chloride (13454-96-1) → bis(1-ethyl-3-methylimidazolium) hexachloroplatinate(IV)

Conditions	Yield
In neat (no solvent) under N2 using Schlenk techniques; heating at 150°C for 1 h; cooling to room temp.; washed (dry benzene); recrystd. (acetonitrile/benzene); elem.anal.;	80%

2-Mercaptopyridine (2637-34-5) + platinum(IV) chloride (13454-96-1) + cis-1,2-bis-(diphenylphosphino)ethene (983-80-2) → cis-[Pt(η1-S-pyridine-2-thiolato)2(1,2-bis(diphenylphosphino)ethene)] (285547-29-7)

Conditions	Yield
With Et3N In ethanol; benzene byproducts: Et3N*HCl; pyridine-2-thione in benzene with Et3N was added dropwise to soln. of PtCl4 in ethanol under stirring, solid ligand was added, stirred for 24 h; filtered, evapd. slowly, elem. anal.;	80%

2-Mercaptopyridine (2637-34-5) + platinum(IV) chloride (13454-96-1) + 1,2-bis-(diphenylphosphino)ethane (1663-45-2) → cis-[Pt(η1-S-pyridine-2-thiolato)2(1,2-bis(diphenylphosphino)ethane)] (285547-28-6)

Conditions	Yield
With Et3N In ethanol; benzene byproducts: Et3N*HCl; pyridine-2-thione in benzene with Et3N was added dropwise to soln. of PtCl4 in ethanol under stirring, solid ligand was added, stirred for 24 h; filtered, evapd. slowly, elem. anal.;	80%

water (7732-18-5) + platinum(IV) chloride (13454-96-1) + 1-(p-anisyl)-5-aminoimidazole-4-carboxamide (93270-70-3) → [Pt(5-amino-1-(p-CH3OC6H4)imidazole-4-carboxamide)2(H2O)2]Cl4*2H2O

Conditions	Yield
In ethanol; water mixed hot 1:1 EtOH-water soln. of metal salt with EtOH soln. of ligand in stoich. amts., refluxed; filtered, washed with EtOH and Et2O, dried in desiccator over anhyd. CaCl2, elem. anal.;	80%

pyridinioacetate (24608-93-3) + water (7732-18-5) + platinum(IV) chloride (13454-96-1) → [Pt(2-(pyridin-1-ium-1-yl)acetate)2(H2O)3/2Cl2]Cl2

Conditions	Yield
In ethanol for 1.5h; Reflux;	80%

platinum(IV) chloride (13454-96-1) + 1-phenyl-3-n-hexyltriazene → tetrakis(η1-1-phenyl-3-n-hexyltriazenido)platinum(IV)

Conditions	Yield
With n-butyllithium In tetrahydrofuran byproducts: LiCl; dropwise addn. of n-butyllithium soln. (n-hexane) to triazene soln. (THF)with stirring excluding light and moisture, 15°C; after 30 min addn. of PtCl4; stirring, room temp., 12h; evapn.; dissoln. in hexamethyldisiloxane of 40°C; filtration; crystn. at 4°C within 2 d;	79.5%

3-(2-(3-chlorophenyl)hydrazono)pentane-2,4-dione (24756-06-7) + platinum(IV) chloride (13454-96-1) → [Pt(3-[(3-chlorophenyl)hydrazono]pentane-2,4-dione)2Cl2]Cl2

Conditions	Yield
In acetone at 20℃; for 24h;	78.6%

2-Mercaptopyridine (2637-34-5) + (diphenylphosphinomethyl)diphenylphosphine selenide (23176-19-4) + platinum(IV) chloride (13454-96-1) → cis-[Pt(η1-S-pyridine-2-thiolato)2(dppmPSe)] (285547-33-3)

Conditions	Yield
With Et3N In ethanol; benzene byproducts: Et3N*HCl; pyridine-2-thione in benzene with Et3N was added dropwise to soln. of PtCl4 in ethanol under stirring, solid ligand was added, stirred for 24 h; filtered, evapd. slowly, elem. anal.;	78%

2-Mercaptopyridine (2637-34-5) + platinum(IV) chloride (13454-96-1) + 1,4-di(diphenylphosphino)-butane (7688-25-7) → cis-[Pt(η1-S-pyridine-2-thiolato)2(1,4-bis(diphenylphosphino)butane)] (285547-31-1)

Conditions	Yield
With Et3N In ethanol; benzene byproducts: Et3N*HCl; pyridine-2-thione in benzene with Et3N was added dropwise to soln. of PtCl4 in ethanol under stirring, solid ligand was added, stirred for 24 h; filtered, evapd. slowly, elem. anal.;	78%

C14H10N4O4S (1415685-09-4) + platinum(IV) chloride (13454-96-1) → C28H19N8O8PtS2(2+)*2Cl(1-)*H2O

Conditions	Yield
In ethanol at 60 - 70℃;	78%

platinum(IV) chloride (13454-96-1) + mercury (II) chloride (7487-94-7) + lithium chloride → Li(x)Pt3O4

Conditions	Yield
In neat (no solvent) heating mixt. of LiCl, HgCl2 and PtCl4 (molar ratio 1:2:3) under steam at 425°C overnight; treated with warm aqua regia;	77%

[2,2]bipyridinyl (366-18-7) + Homophthalic acid (89-51-0) + platinum(IV) chloride (13454-96-1) → 2,2'-bipyridine platinum(IV) homophthalate (139940-17-3)

Conditions

Yield

With KOH In water byproducts: HCl; soln. of PtCl4 in distd. H2O was mixed homogeneously with soln. of homophthalic acid in ethanol and refluxed for 1h, pH raised to 6.0 by addn. of ethanolic KOH, soln. of 2,2'-bipyridine in ethanol was added, heated at 70 °C for 1h, cooled;; formed ppt. was filtered, washed several times successively with distd. H2O and ethanol, dried in a vacuum desiccator over silica gel; elem. anal.;;

76%

1-vinylimidazole (1072-63-5) + platinum(IV) chloride (13454-96-1) → [dichlorotetrakis(1-vinylimidazole)platinum(IV)] chloride

Conditions	Yield
In water refluxed for 3 h; distd., cooled, poured into ice, ppt. is washed with ethanol and ether,dried in vac.;	75%
In ethanol refluxed for 3 h; distd., cooled, poured into ice, ppt. is filtd., dried in vac.;	65%
In acetone the azole is added to a soln. of PtCl4 in acetone with intense stirring(ratio PtCl4:azole 1:8); the ppt. is recrystd. from methanol, dried in vac., elem. anal.;	25%

2-Mercaptopyridine (2637-34-5) + 1,3-bis-(diphenylphosphino)propane (6737-42-4) + platinum(IV) chloride (13454-96-1) → cis-[Pt(η1-S-pyridine-2-thiolato)2(1,3-bis(diphenylphosphino)propane)] (285547-30-0)

Conditions	Yield
With Et3N In ethanol; benzene byproducts: Et3N*HCl; pyridine-2-thione in benzene with Et3N was added dropwise to soln. of PtCl4 in ethanol under stirring, solid ligand was added, stirred for 24 h; filtered, evapd. slowly, elem. anal.;	75%

2-Mercaptopyridine (2637-34-5) + (diphenylphosphinomethyl)diphenylphosphine sulphide (54006-28-9) + platinum(IV) chloride (13454-96-1) → cis-[Pt(η1-S-pyridine-2-thiolato)2(dppmPS)] (285547-32-2)

Conditions	Yield
With Et3N In ethanol; benzene byproducts: Et3N*HCl; pyridine-2-thione in benzene with Et3N was added dropwise to soln. of PtCl4 in ethanol under stirring, solid ligand was added, stirred for 24 h; filtered, evapd. slowly, elem. anal.;	75%

water (7732-18-5) + platinum(IV) chloride (13454-96-1) + 1-(p-tolyl)-5-aminoimidazole-4-carboxamide (93270-67-8) → [Pt(5-amino-1-(p-CH3C6H4)imidazole-4-carboxamide)2(H2O)2]Cl4*2H2O

Conditions	Yield
In ethanol; water mixed hot 1:1 EtOH-water soln. of metal salt with EtOH soln. of ligand in stoich. amts., refluxed; filtered, washed with EtOH and Et2O, dried in desiccator over anhyd. CaCl2, elem. anal.;	73%

Upstream product

• 7647-01-0 hydrogenchloride 
• 7440-06-4 platinum 
• 15619-71-3 PtCl₂I₂ 
• 7790-99-0 Iodine monochloride 
• 7784-34-1 arsenic trichloride 
• 7782-49-2 selenium 
• 10026-03-6 selenium tetrachloride 
• 7782-50-5 chlorine 
• 10034-85-2 hydrogen iodide 
• 916329-38-9 hydrogen azide 
• 10097-32-2 bromine 
• 7553-56-2 iodine 
• 25909-39-1 platinum trichloride 

Downstream Products

• 7440-06-4 platinum 
• 76846-19-0 [NH(CH₂)3]2PtCl₄ 
• 14683-12-6 tellurium 
• 10026-07-0 tellurium tetrachloride 
• 7647-01-0 hydrogenchloride 
• 7727-37-9 nitrogen 
• 10025-65-7 platinum(II) chloride 
• 12038-21-0 platinum(IV) disulfide 
• 118455-74-6 dl-{Pt(PhS(CH₂)3SPh)Cl₂} 
• 88886-22-0 platinum(IV)(chloride)3(1,2,3,4,9,9a-hexahydro-6,9a-di-p-tolylpyrimido[2,1-c][1,4]thiazine)(H₂O) chloride*H₂O 

Relevant articles and documents

Thermodynamic characteristics of thermal dissociation of platinum tetrachloride

The pressure of thermal dissociation of platinum tetrachloride by the first step PtCl4(s) = PtCl3(s) + 0.5 Cl2(g) was measured by the static method with a quartz membrane-gauge zero-pressure manometer. An approximating equation for the dissociation pressure vs. temperature was found. The enthalpy (52160±880 J mol-1) and entropy (72.1±1.6 J mol-1 K-1) of dissociation were calculated. The heat of formation found for platinum tetrachloride (-246.3±1.3 kJ mol-1) at 298.15 K agrees well with the value obtained by the calorimetric method (-245.6±1.9 kJ mol-1).

Outer-sphere electron transfer from platinum(II) to Keggin-type 12-tungstocobaltate(III) in the presence and absence of chloride ions

The reaction between Pt(II) and [CoIIIW12I 40]5- proceeds with two, one-electron steps involving formation of unstable Pt(III) followed by its reaction with another oxidant. The reaction rate is unaffected by the [H+] as there are no protonation equlibria involved with both the reactants whereas, chloride ion accelerates the reaction and the reaction follows chloride independent and dependent paths leading to a two term rate law, rate= {k1 + Kk 2 [Cl-]} [Pt(II)] [CoIIIW12O 40]5-. The chloride ion dependent path is due to rapid substitution of chloride ion on PtCl42-. The products formed have been found to be PtCl4(aq) and PtC6 2- in the absence and presence of chloride ion respectively. Increase in the ionic strength and decrease in the relative permittivity of the medium increase the rate of the reaction. This is due to the formation of an outer-sphere complex between the two reactants. The activation parameters in the presence and absence of chloride ions have also been determined and the values support the proposed mechanism.

Anti-tumor platinum complexes

Platinum complexes, having anti-tumor activity, which include at least one functional ketone group or aldehyde, optionally conjugated as a linkable hydrazone complex. The functional ketone and aldehyde groups and the functionalized hydrazone complexes are