10132-05-5

Basic information

• Product Name: 1,4-DIPHENYLPHTHALAZINE
• Synonyms: 1,4-DIPHENYLPHTHALAZINE
• CAS NO: 10132-05-5
• Molecular Formula: C₂₀H₁₄N₂
• Molecular Weight: 0
• Mol File: 10132-05-5.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1,4-DIPHENYLPHTHALAZINE(CAS DataBase Reference)
• NIST Chemistry Reference: 1,4-DIPHENYLPHTHALAZINE(10132-05-5)
• EPA Substance Registry System: 1,4-DIPHENYLPHTHALAZINE(10132-05-5)

Safety Data

• Hazardous Substances Data: 10132-05-5(Hazardous Substances Data)

Usage

Physical state

Crystalline solid

Solubility

Insoluble in water, soluble in organic solvents

Vasodilator

Ability to widen blood vessels

Treatment of hypertension

Potential use in managing high blood pressure

Antitumor agent

Investigated for its ability to inhibit tumor growth

Antiviral agent

Explored for its potential to combat viral infections

Research status

Further research needed to fully understand its pharmacological properties and potential medical applications.

Upstream product

• 1159-86-0 o-dibenzoylbenzene 
• 105941-93-3 C₂₇H₂₂N₂O₃S 
• 574-98-1 2-(2-bromoethyl)isoindoline-1,3-dione 
• 17494-19-8 2,3-dihydro-9b-phenyloxazolo<2,3-a>isoindol-5(9bH)-one 
• 591-51-5 phenyllithium 
• 13047-06-8 o-bromobenzophenone 
• 105941-87-5 N’-((2-bromophenyl)-(phenyl)methylene)-4-methylbenzenesulfonohydrazide 
• 98-88-4 benzoyl chloride 
• 6830-78-0 3,6-diphenyl-1,2,4,5-tetrazine 
• 118-92-3 anthranilic acid 
• 88284-48-4 2-(trimethylsilyl)phenyl trifluoromethanesulfonate 

Downstream Products

• 104240-10-0 C₂₀H₁₄N₂^(2-)*2Na⁽¹⁺⁾ 
• 106200-50-4 1,2-dihydro-1,4-diphenylphthalazine 
• 106200-49-1 1,2-dimethyl-1,2-dihydro-1,4-diphenylphthalazine 
• 106200-54-8 6,10b-diphenylpyrrolidino<2,1-a>phthalazine 
• 106200-52-6 1-benzyl-1,2-dihydro-1,4-diphenylphthalazine 
• 106200-53-7 2-Benzyl-1,4-diphenyl-1,2-dihydro-phthalazine 
• 106200-55-9 7,11b-diphenylpiperidino<2,1-a>phthalazine 
• 106200-56-0 1,2-dicarbomethoxy-1,2-dihydro-1,4-diphenylphthalazine 
• 1159-86-0 o-dibenzoylbenzene 

Relevant articles and documents

Triple aryne-tetrazine reaction enabling rapid access to a new class of polyaromatic heterocycles

One of the most challenging goals of modern synthetic chemistry is to develop multi-step reactions for rapid and efficient access to complex molecules. We report a triple aryne-tetrazine reaction that enables rapid access to a new class of polyaromatic heterocycles. This new reaction, which couples diverse reactivity modes between simple aryne and tetrazine starting materials, proceeds in a single operation and takes less than 5 minutes in air with no metal catalyst.

A concise method to prepare linear 2,3-diazaoligoacene derivatives

In this Letter, we demonstrate that linear 2,3-diazanaphthalene (1), 2,3-diazaanthracene (2), and 2,3-diazatetracene (3) can be easily prepared through [4+2] cycloaddition reaction between 3,6-diphenyl-1,2,4,5-tetrazine as the diene and arynes as dienophiles, generated in situ from ortho- aminoarylcarboxylic acids. The physical properties and crystal packing of the prepared compounds 1-3 were fully investigated. In addition, the experimental data (e.g., band gap and band position) are further confirmed by theoretical studies.

Red-emitting electrophosphorescent devices

This invention relates to an organic electroluminescence (EL) device and to the use of a tris-cyclometalated iridium complex with a 3-Phenyl-azine ligand for thin-film type organic electroluminescence devices. The iridium complexes used have the following

NOVEL USE OF TRICYCLIC COMPOUND

Pharmaceutical compositions for enhancing the expression of apoAI are provided, which are used as medicaments for treatment of cardiovascular diseases on the basis of improving the functions of HDL.Pharmaceutical compositions for enhancing the expression of apoAI which comprises a compound of formula (I): in which X1 and X2 are independently an aryl or heteroaryl that may be optionally substituted, a hydrogen, a halogen, or the like; ring A is a benzene ring or 6-membered aromatic heterocyclic ring containing 1 to 3 N atoms that may be optionally condensed with another aromatic ring; R1 to R4 are independently a hydrogen, a halogen, a lower alkyl, a lower alkoxy or the like; a prodrug thereof, a pharmaceutically acceptable salt or solvate of them are disclosed.

THE GENERATION AND REACTIONS OF C,N-DIANIONS OF AROMATIC TOSYLHYDRAZONES: ortho-N-DILITHIATED BENZOPHENONE TOSYLHYRAZONE

The ortho, N-dilithiated derivative of the tosylhydrazone of benzophenone (5) has been generated by metal-halogen exchange at low temperature.A range of alkylation, silylation and acylation reactions are described together with further reactions leading to 1,2-diacylbenzenes, phthalazines, 1,3-diphenylisobenzofuran, and a 1,2,3-diazaborine.

Synthesis and Reactions of 2,3-Dihydro-oxazoloisoindol-5(9bH)-ones

The synthesis and reactions with nucleophiles of 2,3-dihydro-oxazoloisoindol-5(9bH)-ones are described.