105941-87-5

Upstream product

• 13047-06-8 o-bromobenzophenone 
• 1576-35-8 toluene-4-sulfonic acid hydrazide 
• 7154-66-7 2-bromobenzoic acid chloride 
• 71-43-2 benzene 
• 88-65-3 2-bromobenzoic-acid 
• 98-88-4 benzoyl chloride 

Downstream Products

• 105941-95-5 4-Phenyl-2-(toluene-4-sulfonyl)-2H-phthalazin-1-one 
• 105941-92-2 C₂₅H₂₆N₂O₃S 
• 5471-63-6 1,3-diphenylisobenzofuran 
• 105941-93-3 C₂₇H₂₂N₂O₃S 
• 105941-89-7 C₂₂H₂₂N₂O₂S 
• 105941-90-0 C₂₃H₂₄N₂O₂S 
• 10282-57-2 2-bromobenzanilide 
• 13097-01-3 3-phenyl-1H-indazole 
• 1244620-46-9 1-bromo-2-(phenyl(tosyl)methyl)benzene 
• 105941-88-6 C₂₂H₂₂N₂O₂S 
• 1159-86-0 o-dibenzoylbenzene 
• 105941-94-4 1-Furan-2-yl-4-phenyl-phthalazine 
• 52540-15-5 1-(2-benzoylphenyl)-2,2-dimethylpropan-1-one 
• 10132-05-5 1,4-diphenyl-2,3-diazanaphthalene 

Relevant academic research and scientific papers

Rhodium-catalyzed oxidative annulation of sulfonylhydrazones with alkenes

An efficient rhodium-catalyzed tandem C-H bond olefination and annulation approach was developed to afford 1,2-dihydrophthalazines in good to excellent yields from easily accessible sulfonylhydrazones and alkenes.

Copper-catalyzed nitrogen loss of sulfonylhydrazones: A reductive strategy for the synthesis of sulfones from carbonyl compounds

Figure Presented. An efficient method for the synthesis of sulfones via nitrogen loss of sulfonyl hydrazones is described. The reaction was performed in the presence of simple copper salt and base by utilization of sulfonyl hydrazones, which were easily p

Synthesis of 3-substituted indazoles and benzoisoxazoles via Pd-catalyzed cyclization reactions: application to the synthesis of nigellicine

Syntheses of 3-substituted indazoles and benzoisoxazoles were efficiently accomplished with the aid of Pd-catalyzed intramolecular carbon-nitrogen and carbon-oxygen bond formations. The catalyst system described herein allows the cyclization to proceed under very mild conditions and thus could be applied to a wide range of substrates with acid- or base-sensitive functional groups. A total synthesis for the indazole ring-containing natural product nigellicine is also described.

Palladium-catalyzed C-H activation/intramolecular amination reaction: A new route to 3-aryl/alkylindazoles

A method for the catalytic C-H activation of hydrazone compounds followed by intramolecular amination is described. It requires the use of a catalytic amount of Pd(OAc)2 in the presence of Cu(OAc)2 and AgOCOCF3, which effi

Efficient synthesis of 3-substituted indazoles using Pd-catalyzed intramolecular amination reaction of N-tosylhydrazones

The efficient method for the preparation of 3-substituted indazoles was developed using the palladium catalyzed intramolecular animation reaction of 2-bromophenyl hydrazone derivatives. Good functional group compatibility was observed under mild reaction

Diazotisation Rearrangement of Tosylhydrazones of ortho- and meta-Substituted-benzophenones and α-Substituted-acetophenones (Synthesis of Anilides)

Ortho and meta-substituted-benzophenones (1a-g) and substituted-acetophenones (1h-i) were converted into tosylhydrazones (2a-i) by reacting with p-toluenesulphonyl-hydrazide.Conversion of 2a-i to the anilides (3a-i) was effected with the reagents H2SO4 and NaNO2, and was found to be as facile as in case of the para-substituted-benzophenone hydrozones.

THE GENERATION AND REACTIONS OF C,N-DIANIONS OF AROMATIC TOSYLHYDRAZONES: ortho-N-DILITHIATED BENZOPHENONE TOSYLHYRAZONE

The ortho, N-dilithiated derivative of the tosylhydrazone of benzophenone (5) has been generated by metal-halogen exchange at low temperature.A range of alkylation, silylation and acylation reactions are described together with further reactions leading to 1,2-diacylbenzenes, phthalazines, 1,3-diphenylisobenzofuran, and a 1,2,3-diazaborine.