101861-59-0

Basic information

• Product Name: 3,5-dibromo-quinoline
• Synonyms: 3,5-dibromo-quinoline;EOS-61483
• CAS NO: 101861-59-0
• Molecular Formula: C9H5Br2N
• Molecular Weight: 287
• Mol File: 101861-59-0.mol

Chemical Properties

• Melting Point: 86℃
• Boiling Point: 333.054 °C at 760 mmHg
• Flash Point: 155.226 °C
• Appearance: /
• Density: 1.924 g/cm³
• CAS DataBase Reference: 3,5-dibromo-quinoline(CAS DataBase Reference)
• NIST Chemistry Reference: 3,5-dibromo-quinoline(101861-59-0)
• EPA Substance Registry System: 3,5-dibromo-quinoline(101861-59-0)

Safety Data

• Hazardous Substances Data: 101861-59-0(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
3,5-dibromoquinoline is used as a building block for the synthesis of pharmaceuticals, contributing to the development of new drugs and therapeutic agents. Its chemical structure allows for the creation of diverse molecules with potential medicinal properties.
Used in Agrochemical Industry:
In the agrochemical sector, 3,5-dibromoquinoline is employed as a component in the synthesis of agrochemicals, such as pesticides and herbicides. Its incorporation into these products can enhance their effectiveness in controlling pests and weeds in agricultural settings.
Used in Dye Industry:
3,5-dibromoquinoline is used as a precursor in the production of dyes, particularly those intended for various industrial applications. Its chemical properties enable the creation of dyes with specific color characteristics and stability.
Used in Organic Light-Emitting Diodes (OLEDs):
3,5-dibromoquinoline has been studied for its potential use in the development of organic light-emitting diodes (OLEDs), which are utilized in the production of advanced display technologies and lighting systems. Its chemical properties may contribute to improved OLED performance and efficiency.
Used as an Antifungal Agent:
3,5-dibromoquinoline has shown promise as an antifungal agent, with potential applications in the treatment and prevention of fungal infections. Its chemical structure may enable it to inhibit the growth of various fungal species, offering a new avenue for antifungal therapy.

Upstream product

• 116632-57-6 3-bromoquinolin-5-amine 
• 116632-33-8 3-bromo-5-nitroquinoline 
• 5332-24-1 3-bromoquinoline 
• 116632-25-8 3,5-dibromo-[6]quinolylamine 

Downstream Products

• 776296-12-9 5-bromo-3-methoxyquinoline 
• 881656-52-6 3-methoxy-quinoline-5-carbaldehyde 

Relevant articles and documents

Design, synthesis, and characterization of novel tetrahydropyran-based bacterial topoisomerase inhibitors with potent anti-gram-positive activity

There is an urgent need for new antibacterial drugs that are effective against infections caused by multidrug-resistant pathogens. Novel nonfluoroquinolone inhibitors of bacterial type II topoisomerases (DNA gyrase and topoisomerase IV) have the potential

5-Quinoline derivatives having an anti-bacterial activity

The present invention describes novel anti-bacterial compounds of the formula (I). These compounds are, amongst others, of interest as inhibitors of DNA gyrase and topoisomerases, for example of topoisomerase II and IV.

CYCLOHEXYL OR PIPERIDINYL CARBOXAMIDE ANTIBIOTIC DERIVATIVES

The invention relates to antibiotic cyclohexyl or piperidinyl carboximide derivatives of formula (I) wherein R1 represents hydrogen, halogen, (C1-C4)alkyl, (C1-C4)alkoxy, cyano or COOR2, R2 being (C1-C4)alkyl;one or two of U, V, W and X represent(s) N and the remaining represent each CH, or, in the case of X, may also represent CRX, RX being a halogen atom;either B represents N and A represents CH2CH2 or CH(OR3)CH2, or B represents CH or C(OR4) and A represents OCH2, CH2CH(OR5), CH(OR6)CH2, CH(OR7)CH(OR8), CH═CH or CH2CH2;each of R3, R4, R5, R6, R7, and R8 represents independently hydrogen, SO3H, PO3H2, CH2OPO3H2 or COR9, R9 being either CH2CH2COOH or such that R9—COOH is naturally occurring amino acid or dimethylaminoglycine;and to salts of such compounds of formula (I).

ETHANOL OR 1,2-ETHANEDIOL CYCLOHEXYL ANTIBIOTIC DERIVATIVES

The invention relates to antibiotic ethanol or 1,2-ethanediol cyclohexyl derivatives of formula (I) wherein R1 represents (C1-C4)alkoxy; one or two of U, V, W and X represent(s) N and the remaining represent each independently CH or, in the case of V or X

CYCLOHEXYL OR PIPERIDINYL CARBOXAMIDE ANTIBIOTIC DERIVATIVES

The invention relates to antibiotic cyclohexyl or piperidinyl carboxamide derivatives of formula (I) wherein R1 represents hydrogen, halogen, (C1-C4)alkyl, (C1-C4)alkoxy, cyano or COOR2, R2 being (C1-C4)alkyl; one or two of U, V, W and X represent(s) N and the remaining represent each CH, or, in the case of X, may also represent CRx, Rx being a halogen atom; either B represents N and A represents CH2CH2 or CH(OR3)CH2, or B represents CH or C(OR4) and A represents OCH2, CH2CH(OR5), CH(OR6)CH2, CH(OR7)CH(OR8), CH=CH or CH2CH2; each of R3, R4, R5, R6, R7 and R8 represents independently hydrogen, SO3H, PO3H2, CH2OPO3H2 or COR9, R9 being either CH2CH2COOH or such that R9-COOH is a naturally occurring amino acid or dimethylaminoglycine; and to salts of such compounds of formula (I).

New Piperidine Antibiotics

The invention relates to novel, antibacterially active piperidine derivatives of the formula wherein one of U and V represents N, the other represents N or CH; M represents CH2CH2, CH═CH, CH(OH)CH(OH), CH(OH)CH2, CH(NHsub

TETRAHYDROPYRANE ANTIBIOTICS

The invention relates to antibiotic tetrahydro rane derivatives of formula (I).

ANTIBIOTIC COMPOUNDS

The invention relates to selected antibiotics of formula (Al) wherein R1 represents alkyl, alkoxy, haloalkoxy, halogen or cyano; one or two of U, V, W and X represent(s) N, the remaining represent CH, or, in case of U, V and/or W, may also repr

NOVEL COMPOUNDS HAVING AN ANTI-BACTERIAL ACTIVITY

The present invention describes novel anti-bacterial compounds of formula (I). These compounds are, amongst others, of interest as inhibitors of DNA gyrase.

NEW PIPERIDINE ANTIBIOTICS

The invention relates to novel, antibacterially active piperidine derivatives of the formula (I) wherein one of U and V represents N, the other represents N or CH; M represents CH2CH2, CH=CH, CH(OH)CH(OH), CH(OH)CH2, CH(NH