1035404-19-3

Basic information

• Product Name: ethyl 2-(2-(2-(4-chlorophenoxy)phenyl)-N-MethylacetaMido)acetate
• Synonyms: ethyl 2-(2-(2-(4-chlorophenoxy)phenyl)-N-MethylacetaMido)acetate
• CAS NO: 1035404-19-3
• Molecular Formula: C₁₈H₁₈ClNO₄
• Molecular Weight: 361.8194
• Mol File: 1035404-19-3.mol

Chemical Properties

• Boiling Point: 474.9±45.0 °C(Predicted)
• Appearance: /
• Density: 1.248±0.06 g/cm3(Predicted)
• PKA: -1.18±0.70(Predicted)
• CAS DataBase Reference: ethyl 2-(2-(2-(4-chlorophenoxy)phenyl)-N-MethylacetaMido)acetate(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl 2-(2-(2-(4-chlorophenoxy)phenyl)-N-MethylacetaMido)acetate(1035404-19-3)
• EPA Substance Registry System: ethyl 2-(2-(2-(4-chlorophenoxy)phenyl)-N-MethylacetaMido)acetate(1035404-19-3)

Safety Data

• Hazardous Substances Data: 1035404-19-3(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
Ethyl 2-(2-(2-(4-chlorophenoxy)phenyl)-N-MethylacetaMido)acetate is used as a building block for the synthesis of various pharmaceuticals. Its unique structure allows it to be a key component in the development of new drugs, particularly those targeting specific biological pathways or receptors.
Used in Agrochemical Industry:
In the agrochemical sector, ethyl 2-(2-(2-(4-chlorophenoxy)phenyl)-N-MethylacetaMido)acetate is utilized as a precursor in the production of pesticides and other agrochemicals. Its chemical properties make it suitable for creating compounds that can effectively control pests and diseases in agriculture.
Used in Research and Development:
Ethyl 2-(2-(2-(4-chlorophenoxy)phenyl)-N-MethylacetaMido)acetate is also used in research and development for exploring its potential pharmacological properties. Studies are being conducted to investigate its role as a potential antifungal and antibacterial agent, which could lead to the development of new treatments for various infections.
It is crucial to handle ethyl 2-(2-(2-(4-chlorophenoxy)phenyl)-N-MethylacetaMido)acetate with care, as it may pose health and environmental risks if not properly managed. Proper safety measures and disposal methods should be followed to minimize any potential hazards associated with this chemical compound.

Upstream product

• 5473-12-1 N-methylglycine methylester 
• 1035404-18-2 [2-(4-chloro-phenoxy)-phenyl]-acetyl chloride 
• 57486-69-8 methyl 2-(2-bromophenyl)acetate 
• 106-48-9 4-chloro-phenol 
• 13515-93-0 N-methylglycine methyl ester hydrochloride 
• 25563-04-6 o-(p-chlorophenoxy)phenylacetic acid 
• 1366179-34-1 tributylamine salt of 2-(2-(4-chlorophenoxy)phenyl)acetic acid 
• 57486-68-7 methyl (2-chlorophenyl)acetate 
• 2444-36-2 2'-chloro-benzeneacetic acid 

Downstream Products

• 65576-45-6 asenapine 
• 85650-56-2 trans-5-Chloro-2-methyl-2,3,3a,12b-tetrahydro-1H-dibenz<2,3:6,7>oxepino<4,5-c>pyrrolidine maleate 
• 934996-79-9 5-chloro-2-methyl-2,3-dihydro-1H-dibenzo[2,3:6,7]oxepino [4,5-c]pyrrole-1-one 
• 912356-09-3 trans 5-chloro-2,3,3a,12b-tetrahydro-2-methyl-1H-dibenz[2,3:6,7]oxepino[4,5-c]pyrrol-1-one 
• 912356-09-3 cis 5-chloro-2,3,3a,12b-tetrahydro-2-methyl-1H-dibenz[2,3:6,7]oxepino[4,5-c]pyrrol-1-one 
• 1383781-81-4 3-[2-(4-chlorophenoxy)phenyl]-4-hydroxy-1-methylpyrrolidine-2-one 
• 912356-09-3 cis-5-chloro-2,3,3a,12b-tetrahydro-2-methyl-1H-dibenz[2,3:6,7]oxepino[4,5-c]pyrrol-1-one 
• 912356-09-3 trans-11-chloro-2,3,3a,12b-tetrahydro-2-methyl-1H-dibenz[2,3:6,7]oxepino[4,5-c]pyrrol-1-one 

Relevant articles and documents

A process for the preparation of key intermediate asenapine

The invention provides a chemical synthesis method, in particular to a preparation method of a key intermediate [formula (III)] compound of asenapine capable of serving as a schizophrenia drug. In an anhydrous system, the intermediate [formula (III)] compound is obtained through dehydration of an intermediate [formula (II)] compound and anhydride under the action of a catalyst. The invention further provides a novel method for preparing asenapine by the intermediate [formula (III)]. The provided method has the advantages of simple operation, high yield, environment-friendliness, lower cost, stable technology and the like.

PROCESS FOR THE PREPARATION OF (3ARS,12BRS)-5-CHLORO-2-METHYL-2,3,3A12B-TETRAHYDRO-1HDIBENZO[2,3:6,7] OXEPINO [4,5-C]PYRROLE MALEATE AND IT'S PHARMACEUTICAL COMPOSITION THEREOF

The present invention relates to an improved process for the preparation (3aRS,12bRS)-5-Chloro-2-menthyl-2,3,3a,12b-tetrahydro-1Hdibenzo[2,3:6,7]oxepino [4,5-c]pyrrole maleate represented by the compound of formula-1a and its pharmaceutical composition.(F)

Processes for the preparation of 5-chloro-2-methyl-2,3,3a,12b-tetrahydro-1H-dibenzo[2,3:6,7]oxepino[4,5-c]pyrrole

This invention provides improved processes for the preparation of 5-chloro-2-methyl-2,3,3a,12b-tetrahydro-1H-dibenzo[2,3:6,7]oxepino[4,5-c]pyrrole, asenapine. These processes allow the preparation of asenapine at industrial scale in good yields and high stereoselectivity.

Intermediate compounds for the preparation of trans-5-chloro-2-methyl-2,3,3a,12b-tetrahydro-1H-dibenz[2,3:6,7]oxepino[4,5-c]pyrrole

Disclosed are novel amino acid derivatives of formula (I) and (II) processes for the preparation thereof, and their use in the preparation of trans-5-chloro-2-methyl-2,3,3a,12b-tetrahydro-1H-dibenz[2,3:6,7]oxepino-[4,5-c]pyrrole.