10368-47-5

Basic information

• Product Name: 2,4,6-TRIPHENYLNITROBENZENE
• Synonyms: 2,4,6-TRIPHENYLNITROBENZENE;Triphenylnitrobenzene;2,4,6-TRIPHENYLNITROBENZENE 98+%;2,4,6-Triphenyl-1-nitrobenzene;2'-Nitro-5'-phenyl-1,1':3',1''-terbenzene;3,5-Diphenyl-4-nitrobiphenyl;RCL R247081
• CAS NO: 10368-47-5
• Molecular Formula: C₂₄H₁₇NO₂
• Molecular Weight: 351.4
• Mol File: 10368-47-5.mol

Chemical Properties

• Melting Point: 147°C
• Boiling Point: 496.3°C at 760 mmHg
• Flash Point: 220.5°C
• Appearance: /
• Density: 1.182g/cm³
• Vapor Pressure: 1.67E-09mmHg at 25°C
• Refractive Index: 1.636
• CAS DataBase Reference: 2,4,6-TRIPHENYLNITROBENZENE(CAS DataBase Reference)
• NIST Chemistry Reference: 2,4,6-TRIPHENYLNITROBENZENE(10368-47-5)
• EPA Substance Registry System: 2,4,6-TRIPHENYLNITROBENZENE(10368-47-5)

Safety Data

• Statements: 20/21/22
• Safety Statements: 22-36/37/39
• Hazardous Substances Data: 10368-47-5(Hazardous Substances Data)

Usage

Uses

Used in Research and Development:
2,4,6-Triphenylnitrobenzene is used as a precursor in the synthesis of various organic compounds, contributing to the advancement of chemical research and the development of new materials.
Used in Pharmaceutical Industry:
In the pharmaceutical sector, 2,4,6-triphenylnitrobenzene is used as a building block for the production of various pharmaceuticals. Its unique chemical structure allows for the creation of diverse drug molecules with potential therapeutic applications.
Used in Dye Industry:
2,4,6-Triphenylnitrobenzene is utilized in the dye industry for the production of various dyes. Its chemical properties enable the creation of dyes with specific color characteristics and stability.
Used in Agrochemical Industry:
In the agrochemical industry, 2,4,6-triphenylnitrobenzene is employed as a building block for the synthesis of agrochemicals, such as pesticides and herbicides. Its role in the development of these products is crucial for enhancing agricultural productivity and crop protection.
Safety and Environmental Considerations:
2,4,6-Triphenylnitrobenzene is known to be harmful if swallowed, inhaled, or comes into contact with the skin or eyes. Therefore, it should be handled with proper safety precautions to minimize health risks. Additionally, it is considered a potential environmental pollutant, and its disposal should be carried out according to regulations to prevent environmental contamination.

InChI:InChI=1/C24H17NO2/c26-25(27)24-22(19-12-6-2-7-13-19)16-21(18-10-4-1-5-11-18)17-23(24)20-14-8-3-9-15-20/h1-17H

Upstream product

• 75-52-5 nitromethane 
• 448-61-3 2,4,6-triphenylpyrylium tetrafluoroborate 
• 75-65-0 tert-butyl alcohol 
• 612-71-5 1,3,5-triphenylbenzene 
• 7697-37-2 nitric acid 
• 64-19-7 acetic acid 
• 6864-20-6 2,4,6-triphenylaniline 
• 865-47-4 potassium tert-butylate 

Downstream Products

• 1391738-90-1 (2,4-bis(2,4,6-triphenylphenylimido)-3-pentyl)Li(OEt₂) 
• 97388-42-6 3',5'-diphenyl-p-quaterphenyl 
• 97388-40-4 2,4,6-triphenyl-2'-phenylbiphenyl 
• 612-71-5 1,3,5-triphenylbenzene 
• 6864-20-6 2,4,6-triphenylaniline 

Related news

On the electrochemistry of 2,4,6-TRIPHENYLNITROBENZENE (cas 10368-47-5) and related compounds07/29/2019

Cyclic voltammetry at a glassy carbon electrode of 2,4,6-triphenylnitrobenzene (1) in DMF shows two reversible one-electron reductions. Preparative reduction of 1 yields 2,4,6-triphenylaniline under both acidic and alkaline conditions and in DMF in the presence of acetic anhydride. On reduction ...detailed

Relevant articles and documents

Preparation and crystal structure of an oxoimido complex of molybdenum containing the 2,4,6-triphenylphenylimide ligand

Reaction of 2,4,6-triphenylaniline with Na2MoO4 in the presence of SiMe3Cl and NEt3 in 1,2-dimethoxyethane (dme) gave the oxoimido complex [MoCl2(NC6H2Ph3-2,4,6)O(dme)]. Its crystal structure determination showed a distorted octahedron with mutually cis-oxo and imido groups, trans-chloride ligands and the dme oxygen atoms trans to the oxide and imide ligands. The Mo-Nimido and Mo-Ooxo bond lengths [1.756(7) and 1.700(6) A] are consistent with four- and two-electron donor ligands, respectively. The phenyl ring of the imide ligand orientates with the face of one ortho substituent phenyl ring pushing away from a chloride ligand and tilted towards the oxide ligand. The second such phenyl ring tilts away from a chloride ligand but does not push away from the side of the molecule. This occurs as the imido group bends towards the other side of the molecule [Mo-N-C 172.2(7)°] and a methyl group of the dme ligand is severely distorted to remove an interaction with the phenyl ring.

Cobalt schiff base complex-catalyzed oxidation of anilines with tert-butyl hydroperoxide

Cobalt Schiff base complexes [Co(SB)] catalyze the oxidation of anilines (1) with tert-butyl hydroperoxide to give nitrobenzenes 2 and 4-(tert-butylperoxy)-2,5-cyclohexadien-1-imine derivatives 3 in yield distributions depending on the substitution mode of the substrate. 4-Alkyl- and 4-aryl-2,6-di-tert-butylanilines gave mixtures of 2 and 3, where the higher the bulkiness of the 4-substituent, the higher the yield of 2. With 2,4,6-trimethylaniline, the ratio of oxidations of the nitrogen and C-4 atoms was almost the same; but a hydrolyzed product 5 of the imine was obtained. 2,4,6-Triphenylaniline gave only 2. Nitrobenzene derivatives were also obtained from 2,6-dialkylanilines and 4-substituted anilines. The catalytic activity of Co(SB) depended on the nature of the SB ligand: the formal potential E° and steric factors seem to affect the reaction rate. Kinetic studies showed that the key step may involve hydrogen abstraction from the aniline, presumably by t-BuO? generated from homolytic decomposition of initially formed CoIII(SB)(OO-t-Bu). A precursor of 2 was found to be the nitrosobenzene derivative.

Co(salen) catalyzed oxidation of 2,4,6-trisubstituted anilines with tert-butylhydroperoxide

Co(salen) catalyzed oxidation of 2,4,6-trisubstituted (preferentially 2,6-di-tert-butylated) anilines with tert-butylhydroperoxide gives 4-tert-butylperoxy-2,5-cyclohexadien-1-imine and nitrobenzene derivatives. The relative ratio of the products depends on the nature of the substituents in the substrate.