103772-10-7 Usage
Uses
Used in Pharmaceutical Industry:
5-Nitro-2,3,4,5-tetrafluoro benzoyl chloride is used as a key intermediate in the synthesis of pharmaceutical drugs. Its unique chemical structure allows for the development of new and effective medications, contributing to advancements in healthcare and medicine.
Used in Agrochemical Industry:
In the agrochemical sector, 5-Nitro-2,3,4,5-tetrafluoro benzoyl chloride is utilized as a precursor in the production of certain organic compounds. These compounds are further used in the formulation of agrochemicals, such as pesticides and herbicides, to enhance crop protection and improve agricultural productivity.
Used in Organic Synthesis:
5-Nitro-2,3,4,5-tetrafluoro benzoyl chloride is employed as a versatile building block in organic synthesis. Its reactivity and unique functional groups enable the formation of a wide range of organic compounds, which can be used in various applications, including the development of new materials, dyes, and specialty chemicals.
Safety Precautions:
Due to its highly reactive nature and potential hazards, 5-Nitro-2,3,4,5-tetrafluoro benzoyl chloride should be handled with extreme caution. Appropriate safety measures, including the use of personal protective equipment, should be taken to minimize the risk of exposure and accidents. Incompatible materials, such as water, strong oxidizing agents, and strong bases, should be avoided to prevent dangerous reactions.
Check Digit Verification of cas no
The CAS Registry Mumber 103772-10-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,3,7,7 and 2 respectively; the second part has 2 digits, 1 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 103772-10:
(8*1)+(7*0)+(6*3)+(5*7)+(4*7)+(3*2)+(2*1)+(1*0)=97
97 % 10 = 7
So 103772-10-7 is a valid CAS Registry Number.
InChI:InChI=1/C7ClF4NO3/c8-7(14)1-2(9)3(10)4(11)5(12)6(1)13(15)16
103772-10-7Relevant articles and documents
Synthesis and biological activity of 5-amino- and 5-hydroxyquinolones, and the overwhelming influence of the remote N1-substituent in determining the structure-activity relationship
Domagala,Bridges,Culbertson,Gambino,Hagen,Karrick,Porter,Sanchez,Sesnie,Spense,Szotek,Wemple
, p. 1142 - 1154 (2007/10/02)
A series of 5-amino- and 5-hydroxyquinolone antibacterials substituted at C7 with a select group of common piperazinyl and 3-aminopyrrolidinyl side chains was prepared. These 5-substituted derivatives were compared to the analogous 5-hydrogen compounds for antiinfective activity by using DNA gyrase inhibition, minimum inhibitory concentrations against a variety of bacteria, and in vivo efficacy in the mouse infection model. The influence on the structure-activity relationships of varied substituents at C8 (H, F, Cl) and N1 (ethyl, cyclopropyl, difluorophenyl) was also studied. The results showed that several of the structure-activity conclusions regarding side-chain bulk at C7, the effect of halogen at C8, and the effect of the C5-amino group were greatly influenced by the choice of the N1-substituent. Several outstanding broad spectrum quinolones were identified in this work. In particular, the spectrum and potency of the 7-piperazinyl quinolones could be greatly enhanced by the judicious choice of C5-, C8-, and N1-substitutents.
4-oxo-1,4-dihydroquinoline-3-carboxylic acid derivative as antibacterial agents
-
, (2008/06/13)
Novel naphthyridine-, quinoline- and benzoxazinecarboxylic acids as antibacterial agents are described as well as methods for their manufacture, formulation, and use in treating bacterial infections including the description of certain novel intermediates used in the manufacture of the antibacterial agents.
