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1-(4-methylphenyl)piperidin-4-one is a chemical compound with the molecular formula C13H17NO. It is a piperidinone derivative featuring a substituted phenyl group at the 1-position. 1-(4-methylphenyl)piperidin-4-one is characterized by its potential biological activity and serves as a valuable building block in organic synthesis and pharmaceutical development.

105123-89-5

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105123-89-5 Usage

Uses

Used in Pharmaceutical Research and Development:
1-(4-methylphenyl)piperidin-4-one is utilized as a key intermediate in the synthesis of various drugs and organic compounds. Its unique structure and properties make it a promising candidate for the development of new pharmaceuticals with potential therapeutic applications.
Used in Organic Synthesis:
In the field of organic synthesis, 1-(4-methylphenyl)piperidin-4-one is employed as a versatile building block. Its reactivity and functional groups allow for the creation of a wide range of chemical entities, contributing to the advancement of chemical research and the discovery of novel compounds.
Used in Medicinal Chemistry:
1-(4-methylphenyl)piperidin-4-one plays a significant role in medicinal chemistry, where it is used to explore its potential biological activity. Its structure can be modified to enhance or target specific biological pathways, leading to the development of new therapeutic agents.
Used in Drug Discovery:
1-(4-methylphenyl)piperidin-4-one is also used in drug discovery processes, where its properties are evaluated for potential use in treating various diseases and conditions. Its wide range of applications in this field highlights its importance in scientific research and industrial production.

Check Digit Verification of cas no

The CAS Registry Mumber 105123-89-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,5,1,2 and 3 respectively; the second part has 2 digits, 8 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 105123-89:
(8*1)+(7*0)+(6*5)+(5*1)+(4*2)+(3*3)+(2*8)+(1*9)=85
85 % 10 = 5
So 105123-89-5 is a valid CAS Registry Number.
InChI:InChI=1/C12H15NO/c1-10-2-4-11(5-3-10)13-8-6-12(14)7-9-13/h2-5H,6-9H2,1H3

105123-89-5SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 16, 2017

Revision Date: Aug 16, 2017

1.Identification

1.1 GHS Product identifier

Product name 1-(4-methylphenyl)piperidin-4-one

1.2 Other means of identification

Product number -
Other names 1-P-Tolyl-Piperidin-4-One

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:105123-89-5 SDS

105123-89-5Relevant articles and documents

NOVEL TETRAHYDROPYRIDOPYRIMIDINES AND TETRAHYDROPYRIDOPYRIDINES FOR THE TREATMENT AND PROPHYLAXIS OF HEPATITIS B VIRUS INFECTION

-

, (2016/07/27)

The invention provides novel compounds having the general formula (I): wherein R1, R2, R3, Q, U,W, Z, X and Y are as described herein, compositions including the compounds and methods of using the compounds. These compounds are HbsAg inhibitors and are useful as medicaments for the treatment or prophylaxis of HBV infection.

Protection of hydroxy function with 1-N-aryl-4-alkoxy-piperidin-4-yl

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, (2008/06/13)

A process for protecting the 2'-hydroxyl of a nucleoside, which can then be used in the chemical synthesis of polyribonucleotides, comprising the reacting of a protected nucleoside of formula I STR1 wherein B is a nucleoside heterocyclic base and R' is a

A New Synthesis of 1-Arylpiperidin-4-ols

Reese, Colin B.,Thompson, Elizabeth A.

, p. 2881 - 2886 (2007/10/02)

1,5-Dichloropentan-3-ol (8), which is readily prepared from the corresponding ketone (7), reacts with 2-fluoro-, 4-methyl-, 2-chloro-, 3-chloro-, 4-chloro-, and 3-chloro-4-methyl-anilines in the presence of potassium carbonate and sodium iodide in dimethy

AN ACETAL GROUP SUITABLE FOR THE PROTECTION OF 2'-HYDROXY FUNCTIONS IN RAPID OLIGORIBONUCLEOTIDE SYNTHESIS

Reese, Colin B.,Serafinowska, Halina T.,Zappia, Giovanni

, p. 2291 - 2294 (2007/10/02)

The 1--4-methoxypiperidin-4-yl has an acid lability similar to that of the 4-methoxytetrahydropyran-4-yl (Mthp) protecting group under mild hydrolytic conditions ; however, under the relatively more drastic conditions required for the complete removal of a 9-phenylxanthen-9-yl (Px) group, the Ctmp protecting group remains virtually intact.

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