111043-09-5

Basic information

• Product Name: 1-(3-bromopyridin-2-yl)ethanone
• Synonyms: 1-(3-bromopyridin-2-yl)ethanone
• CAS NO: 111043-09-5
• Molecular Formula: C7H6BrNO
• Molecular Weight: 200.03264
• Mol File: 111043-09-5.mol

Chemical Properties

• Boiling Point: 246.0±25.0 °C(Predicted)
• Appearance: /
• Density: 1.534±0.06 g/cm3(Predicted)
• Storage Temp.: Inert atmosphere,Room Temperature
• PKA: 0.40±0.10(Predicted)
• CAS DataBase Reference: 1-(3-bromopyridin-2-yl)ethanone(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(3-bromopyridin-2-yl)ethanone(111043-09-5)
• EPA Substance Registry System: 1-(3-bromopyridin-2-yl)ethanone(111043-09-5)

Safety Data

• Hazardous Substances Data: 111043-09-5(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
1-(3-Bromopyridin-2-yl)ethanone is used as a key intermediate for the synthesis of pharmaceuticals, contributing to the development of new drugs and therapeutic agents. Its unique structure allows for versatile chemical transformations, facilitating the creation of diverse medicinal compounds.
Used in Agrochemical Industry:
In the agrochemical sector, 1-(3-Bromopyridin-2-yl)ethanone serves as an essential component in the production of agrochemicals. It aids in the synthesis of various pesticides and other agricultural chemicals, enhancing crop protection and yield.
Used in Fine Chemicals Synthesis:
1-(3-Bromopyridin-2-yl)ethanone is utilized as a building block in the synthesis of fine chemicals, which are high-purity chemicals used in various applications such as fragrances, dyes, and specialty chemicals.
Used in Research and Development:
1-(3-Bromopyridin-2-yl)ethanone is employed in the research and development of new chemical entities, playing a crucial role in advancing scientific knowledge and innovation in the chemical and pharmaceutical fields.
Used as a Reagent in Organic Synthesis:
1-(3-Bromopyridin-2-yl)ethanone functions as a reagent in organic synthesis and chemical transformations, enabling the production of a wide range of organic compounds for various applications. Its properties make it a valuable and versatile compound in chemical and pharmaceutical research.

Upstream product

• 917-64-6 methyl magnesium iodide 
• 55758-02-6 3-bromopyridine-2-carbonitrile 
• 75-16-1 methylmagnesium bromide 
• 1383734-83-5 1-(3-bromopyridin-2-yl)ethanol 
• 405174-97-2 3-bromopicolinaldehyde 

Relevant articles and documents

Effects of structural modifications on the metal binding, anti-amyloid activity, and cholinesterase inhibitory activity of chalcones

As the number of individuals affected with Alzheimer's disease (AD) increases and the availability of drugs for AD treatment remains limited, the need to develop effective therapeutics for AD becomes more and more pressing. Strategies currently pursued include inhibiting acetylcholinesterase (AChE) and targeting amyloid-β (Aβ) peptides and metal-Aβ complexes. This work presents the design, synthesis, and biochemical evaluation of a series of chalcones, and assesses the relationship between their structures and their ability to bind metal ions and/or Aβ species, and inhibit AChE/BChE activity. Several chalcones were found to exhibit potent disaggregation of pre-formed N-biotinyl Aβ1-42 (bioAβ42) aggregates in vitro in the absence and presence of Cu2+/Zn2+, while others were effective at inhibiting the action of AChE.

OXINDOLE COMPOUNDS CARRYING A NITROGEN-BOUND SPIRO SUBSTITUENT AND USE THEREOF FOR TREATING VASOPRESSIN-RELATED DISEASES

The present invention relates to novel substituted oxindole derivatives of the formula I wherein A is a ring selected from phenyl and 6-membered hetaryl containing 1 or 2 nitrogen atoms as ring members, where ring A carries one substituent R6 a

PYRAZOLOPIPERIDINE COMPOUNDS AS CCR1 RECEPTOR ANTAGONISTS

Disclosed are compounds of the formula (I), useful for treating a variety of diseases and disorders that are mediated or sustained through the activity of CCR1 including autoimmune diseases, such as rheumatoid arthritis and multiple sclerosis. Also disclosed are methods of making and methods of using same.