112137-63-0

Basic information

• Product Name: 2-Deoxy-3,5-di-O-benzoylribofuranose
• Synonyms: 2-Deoxy-3,5-di-O-benzoylribofuranose;2-Deoxy-D-ribofuranose 3,5-Dibenzoate
• CAS NO: 112137-63-0
• Molecular Formula: C₁₉H₁₈O₆
• Molecular Weight: 342.34262
• Product Categories: Aromatics;Carbohydrates & Derivatives;Intermediates;Aromatics, Carbohydrates & Derivatives, Intermediates
• Mol File: 112137-63-0.mol

Chemical Properties

• Appearance: /
• Storage Temp.: Hygroscopic, -20°C Freezer, Under inert atmosphere
• Solubility: Chloroform (Slightly), Ethyl Acetate (Slightly)
• Stability: Hygroscopic
• CAS DataBase Reference: 2-Deoxy-3,5-di-O-benzoylribofuranose(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Deoxy-3,5-di-O-benzoylribofuranose(112137-63-0)
• EPA Substance Registry System: 2-Deoxy-3,5-di-O-benzoylribofuranose(112137-63-0)

Safety Data

• Hazardous Substances Data: 112137-63-0(Hazardous Substances Data)

Usage

Uses

Used in Organic Synthesis:
2-Deoxy-3,5-di-O-benzoylribofuranose is used as an intermediate in organic synthesis for the creation of complex organic molecules. Its unique structure allows for selective functionalization and modification, making it a versatile building block for the synthesis of a wide range of compounds, including pharmaceuticals, agrochemicals, and other specialty chemicals.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 2-Deoxy-3,5-di-O-benzoylribofuranose is utilized as a key component in the development of novel drug candidates. Its unique chemical properties enable the design and synthesis of new molecules with potential therapeutic applications, contributing to the advancement of drug discovery and development.
Used in Research and Development:
2-Deoxy-3,5-di-O-benzoylribofuranose is also employed in research and development settings, where it serves as a valuable tool for studying the properties and reactivity of complex organic molecules. Its use in this context aids in the understanding of fundamental chemical processes and the development of new synthetic strategies and methodologies.

Upstream product

• 98-88-4 benzoyl chloride 
• 108647-88-7 ((2R,3S)-3-(benzoyloxy)-5-methoxytetrahydrofuran-2-yl)methyl benzoate 
• 51255-17-5 (2S,3R)-2-Hydroxymethyl-5-methoxy-tetrahydro-furan-3-ol 
• 51785-70-7 methyl 3,5-dibenzoyloxy-2-deoxy-β-D-erythropentofuranoside 
• 80339-59-9 methyl 3,5-dibenzoyloxy-2-deoxy-α-D-erythropentofuranoside 
• 452-51-7 D-2-deoxyribose 
• 533-67-5 2-deoxy-D-ribose 
• 51255-17-5 1-O-methyl-2-deoxy-D-ribofuranoside 

Downstream Products

• 55734-51-5 1,4-anhydro-2-deoxy-3,5-di-O-benzoyl-D-erythro-pent-1-enitol 
• 140186-56-7 methyl 2,3-O-isopropylidene-5-O-(3,5-di-O-benzoyl-2-deoxy-α-D-ribofuranosyl)-α-D-ribofuranoside 
• 140186-58-9 1,2:5,6-di-O-isopropylidene-3-O-(3,5-di-O-benzoyl-2-deoxy-α-D-ribofuranosyl)-α-D-glucofuranoside 
• 140186-57-8 1,2:3,4-di-O-isopropylidene-5-O-(3,5-di-O-benzoyl-2-deoxy-α-D-ribofuranosyl)-α-D-galactopyranoside 
• 140186-59-0 methyl 2,3-di-O-benzyl-6-O-(3,5-di-O-benzoyl-2-deoxy-α-D-ribofuranosyl)-α-D-glucopyranoside 
• 51255-12-0 1-O-acetyl-3,5-di-O-benzoyl-2-deoxy-D-erythro-pentafuranose 
• 870181-69-4 (2R,3S,5R)-5-(3-Benzooxazol-2-yl-2-hydroxy-phenyl)-2-[bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-tetrahydro-furan-3-ol 
• 870181-65-0 C₃₂H₂₅NO₇ 
• 870181-67-2 (2R,3S,5R)-5-(3-Benzooxazol-2-yl-2-hydroxy-phenyl)-2-hydroxymethyl-tetrahydro-furan-3-ol 
• 870181-62-7 C₁₉H₁₇FO₅ 
• 80311-45-1 C₂₃H₂₄O₇ 
• 80311-45-1 C₂₃H₂₄O₇ 
• 35898-30-7 C₂₄H₂₂N₂O₇ 
• 145417-01-2 2-pyridyl 3,5-di-O-benzoyl-2-deoxy-1-thio-α,β-D-ribofuranoside 

Relevant articles and documents

Iron-Catalyzed Radical Cleavage/C?C Bond Formation of Acetal-Derived Alkylsilyl Peroxides

A novel radical-based approach for the iron-catalyzed selective cleavage of acetal-derived alkylsilyl peroxides, followed by the formation of a carbon–carbon bond is reported. The reaction proceeds under mild reaction conditions and exhibits a broad substrate scope with respect to the acetal moiety and the carbon electrophile. Mechanistic studies suggest that the present reaction proceeds through a free-radical process involving carbon radicals generated by the homolytic cleavage of a carbon–carbon bond within the acetal moiety. A synthetic application of this method to sugar-derived alkylsilyl peroxides is also described.

SYNTHETIC INTERMEDIATE OF 1-(2-DEOXY-2-FLUORO-4-THIO-?-D-ARABINOFURANOSYL)CYTOSINE, SYNTHETIC INTERMEDIATE OF THIONUCLEOSIDE, AND METHOD FOR PRODUCING THE SAME

A compound represented by a formula [1D] as shown below (wherein R1A, R1B, R2A, R2B, R3A and R3B represent a hydrogen atom, an optionally substituted C1-6 alkyl group, and the li

Differential solvation and tautomer stability of a model base pair within the minor and major grooves of DNA

2-(2′-Hydroxyphenyl)benzoxazole (HBO) may be used as a model base pair to study solvation, duplex environment, and tautomerization within the major and minor groves of DNA duplexes. In its ground state, HBO possesses an enol moiety which may be oriented s

A mild and rapid glycosylation reaction between pyrimidine bases and 2-deoxyribofuranosyl N,N,N',N'-tetramethylphosphoroamidates

A trimethylsilyl triflate-mediated coupling reaction to produce protected 2′-deoxynucleosides has been developed by using N,N,N',N'-tetramethylphosphoroamidate as a leaving group. In this reaction, employment of a 3,4,5-trimethoxybenzoyl group as the 3-hydroxyl protective group in the sugar moiety improved the β-stereoselectivity via a novel 1,3-participation.

Stereoselective synthesis of α-linked 2-deoxysaccharides and furanosaccharides by the use of 2-deoxy 2-pyridyl-1-thio pyrano- and furanosides as donors and methyl iodide as an activator

A practical and highly stereoselective glycosidation methodology is described, where anomeric mixture of 2-deoxy 2-pyridyl-1-thiopyranoside donors (1-3,27) have been coupled with several sugar alcohols (4-8,29,31) on activation by methyl iodide to obtain axially linked 2-deoxysaccharides (9-17,30,32,33). Application of this method for the synthesis of disaccharide fragment 28 of avermectin is also described. Utility of this method is also shown by use of 2-pyridyl-1-thiofuranosides (34-36) as donors to prepare α-linked furanosides (42-51).

Improved procedure for the regiospecific synthesis of 2'-deoxyribonucleosides

2'-Deoxyribonucleosides are regiospecifically synthesized in high yields by catalyzing with KI-dibenzo-18-crown-6 PTC the condensation between unprotected silylated purines and pyrimidines and the appropriate easily available 2-deoxy-ribofuranosyl or pyranosyl sugar derivatives.

5(S), 6(R)-5, 7-DIBENZOYLOXY-6-HYDROXYHEPTANOATE ESTER : IMPROVED SYNTHESIS OF A LEUKOTRIENE INTERMEDIATE

The title compound, a key intermediate in the synthesis of leukotriene A4, was prepared by a convenient procedure from 2-deoxy-D-ribose.