112581-95-0

Basic information

• Product Name: 2-BROMOIMIDAZO[1,2-A]PYRIDINE
• Synonyms: 2-Bromoimidazo[1,2-a]pyridine;2-broMoindolizine;IMidazo[1,2-a]pyridine, 2-broMo-;2-broMo-1,5-dihydroiMidazo[1,2-a]pyridine;2-BroMoiMidazo
• CAS NO: 112581-95-0
• Molecular Formula: C7H5BrN2
• Molecular Weight: 197.03
• Product Categories: Heterocycle-Pyridine series
• Mol File: 112581-95-0.mol

Chemical Properties

• Appearance: /
• Density: 1.697 g/cm³
• Refractive Index: 1.688
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• PKA: 3.86±0.50(Predicted)
• CAS DataBase Reference: 2-BROMOIMIDAZO[1,2-A]PYRIDINE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-BROMOIMIDAZO[1,2-A]PYRIDINE(112581-95-0)
• EPA Substance Registry System: 2-BROMOIMIDAZO[1,2-A]PYRIDINE(112581-95-0)

Safety Data

• Hazardous Substances Data: 112581-95-0(Hazardous Substances Data)

Usage

Uses

Used in Organic Chemistry:
2-Bromoimidazo[1,2-a]pyridine is utilized as a synthetic intermediate in organic chemistry for the synthesis of various complex organic molecules. Its unique structure and the presence of the bromide group make it a versatile building block for creating a range of chemical compounds.
Used in Pharmaceutical Synthesis:
In the pharmaceutical industry, 2-Bromoimidazo[1,2-a]pyridine is used as a key intermediate in the development of new drugs. Its reactivity allows for the formation of diverse chemical entities that can possess potential therapeutic properties, contributing to the discovery of novel medications.
Used in Material Science:
2-Bromoimidazo[1,2-a]pyridine can also be employed in material science for the creation of new materials with specific properties. Its ability to form stable compounds can be leveraged to develop materials with tailored characteristics for various applications.
Safety Precautions:
When handling 2-Bromoimidazo[1,2-a]pyridine, it is crucial to take safety precautions due to the potential risks associated with bromine toxicity. Proper protective equipment and handling procedures should be followed to minimize exposure and ensure the safety of those working with this compound.

InChI:InChI=1/C7H5BrN2/c8-6-5-10-4-2-1-3-7(10)9-6/h1-5H

Upstream product

• 504-29-0 2-aminopyridine 
• 126202-06-0 2-(2-imino-1,2-dihydropyridin-1-yl)acetic acid 
• 105-36-2 ethyl bromoacetate 
• 471-25-0 Propiolic acid 

Downstream Products

• 4044-95-5 2-Phenyl-3-bromoimidazo<1,2-a>pyridine 
• 64413-90-7 3-iodo-2-phenylimidazo[1,2-α]pyridine 
• 4105-21-9 2-phenylimidazo[1,2-a]pyridine 
• 1357270-57-5 tert-butyl 1-(4-(3-Iodoimidazo[1,2-a]pyridin-2-yl)phenyl)cyclobutylcarbamate 
• 1356000-04-8 tert-butyl 1-(4-(3-phenylimidazo[1,2-a]pyridin-2-yl)phenyl)cyclobutylcarbamate 
• 1355998-03-6 1-(4-(3-phenylimidazo[1,2-a]pyridin-2-yl)phenyl)cyclobutanamine 
• 3999-29-9 2-phenylimidazo[1,2-a]pyridin-3-amine 
• 54167-76-9 N-(2-phenyl-imidazo[1,2-a]pyridin-3-yl)-acetamide 
• 1452807-20-3 C₁₇H₁₈N₄O 
• 1452807-21-4 C₁₈H₂₀N₄O 
• 1296335-75-5 C₂₀H₂₂N₄O 
• 171628-63-0 1-Phenyl-3-(2-phenyl-imidazo[1,2-a]pyridin-3-yl)-urea 
• 1189902-53-1 C₂₁H₁₈N₄O 
• 1110272-22-4 N,2-diphenylimidazo[1,2-a]pyridin-3-amine 

Relevant articles and documents

A Cu(II)-promoted tandem decarboxylative halogenation and oxidative diamination reaction of 2-aminopyridines with alkynoic acids for the synthesis of 2-haloimidazo[1,2-: A] pyridines

A copper-promoted cascade decarboxylative halogenation and oxidative diamination reaction sequence of 2-aminopyridines with alkynoic acids has been developed for the synthesis of 2-haloimidazo[1,2-a]pyridines. In this reaction, two C-N bonds and one C-halogen bond are formed in one pot, generating the desired products in good yields. This is the first report on the synthesis of 2-haloimidazo[1,2-a]pyridine derivatives from alkynoic acids.

FUSED POLYCYCLIC 2-PYRIDINONE ANTIBACTERIAL COMPOUNDS

The present description relates to fused polycyclic 2-pyridinone compounds and forms and pharmaceutical compositions thereof and methods of using such compounds, forms or compositions thereof for treating or ameliorating a wild-type or drug-resistant form of N. gonorrhoeae or N. meningitides. A compound of Formula (la), Formula (lb) or Formula (Ic), or a form thereof, wherein the dashed lines represent one or more double bonds optionally present where allowed by available valences.

An efficient access to 2,3-diarylimidazo[1,2-a]pyridines via imidazo[1,2-a]pyridin-2-yl triflate through a Suzuki cross-coupling reaction-direct arylation sequence

An efficient method to prepare 2,3-diarylimidazo[1,2-a]pyridines is described. The procedure involves a Suzuki cross-coupling reaction followed by a direct arylation at position 3. Imidazo[1,2-a]pyridin-2-yl triflate was identified as a suitable coupling partner, permitting access to a variety of highly functionalized 2,3-diarylimidazo[1,2-a]pyridines.

Substituted phenylheterocyclic herbicides

This invention relates to certain phenylheterocyclic compounds, herbicidal compositions thereof and a method for their use as general and selective preemergent or postemergent herbicides or plant growth regulants.