cas 117620-85-6, Defluoro Levofloxacin | Articles data ｜lookchem

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117620-85-6

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Synthesis and biological testing of non-fluorinated analogues of Levofloxacin
Quinolones without the usual 6-fluorine substituent have been recently described as potent antibacterial agents. A series of non-fluorinated analogues of the antibacterial quinolone Levofloxacin were synthesized and tested.
Gray, Jeffrey L.,Almstead, Ji-In K.,Gallagher, Corey P.,Hu, X. Eric,Kim, Nick K.,Taylor, Cynthia J.,Twinem, Tracy L.,Wallace, Cynthia D.,Ledoussal, Benoit
p. 2373 - 2375
(2003)
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Chemical Properties

Melting Point: 217-223?C
Boiling Point: 561.4±50.0 °C(Predicted)
Density: 1.43±0.1 g/cm3(Predicted)
Solubility:DMSO (Slightly), Methanol (Slightly, Sonicated, Heated)
Storage Temp.:Refrigerator, Under Inert Atmosphere
PKA: 5?+-.0.40(Predicted)

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