117874-96-1Relevant articles and documents
Cerium(III) chloride: A highly efficient reagent for the synthesis of α-aminonitriles
Pasha,Nanjundaswamy,Jayashankara
, p. 4371 - 4380 (2007)
We report a highly efficient, one-pot, three-component condensation of carbonyl compounds, amines, and TMSCN in MeCN; the reaction is significantly promoted by the catalytic amount of cerium(III) chloride at ambient temperature in excellent yields without any adverse effect on the other substituents. The method afforded an elegant alternative to the synthesis of α- aminonitriles. The reactions are fast and clean, and the products obtained are of high purity. Copyright Taylor & Francis Group, LLC.
H14[NaP5W30O110] as an efficient catalyst for the one-pot synthesis of α-amino nitriles
Oskooie, Hossein A.,Heravi, Majid M.,Bakhtiari, Khadijeh,Zadsirjan, Vahideh,Bamoharram, Fatemeh F.
, p. 1768 - 1770 (2006)
In this study, the synthesis of some α-amino nitriles is reported. The compounds were prepared by the nucleophilic addition reaction of aldehydes and amines with TMSCN in the presence of a catalytic amount of H 14[NaP5W30O110], Preyssler's heteropoly acid, in excellent yields. The catalyst can be recovered and reused in subsequent reactions. Georg Thieme Verlag Stuttgart.
Dehydroascorbic acid (DHAA) capped magnetite nanoparticles as an efficient magnetic organocatalyst for the one-pot synthesis of α-aminonitriles and α-aminophosphonates This article is dedicated to memory of Majid Shahriari
Saberi, Dariush,Cheraghi, Samaneh,Mahdudi, Samaneh,Akbari, Jafar,Heydari, Akbar
, p. 6403 - 6406 (2013)
A dehydroascorbic acid capped magnetite (DHAA-Fe3O4) catalyst is prepared and used for the one-pot synthesis of α-aminonitriles and α-aminophosphonates. Different derivatives of these compounds are synthesized in good yields.
Fe3O4/MIL-101(Fe) nanocomposite as an efficient and recyclable catalyst for Strecker reaction
Mostafavi, Mohammad Mahdi,Movahedi, Farnaz
, (2018/01/05)
A highly porous metal-organic framework, MIL-101(Fe), was prepared by a solvothermal method in the presence of amino-modified Fe3O4@SiO2 nanoparticles, in order to achieve Fe3O4/MIL-101(Fe) nanocomposite, which was characterized by XRD, FT-IR, SEM, TEM, BET, and VSM. This hybrid magnetic nanocomposite was employed as heterogeneous catalyst for α-amino nitriles synthesis through three-component condensation reaction of aldehydes (ketones), amines, and trimethylsilyl cyanide in EtOH, at room temperature. The recoverability and reusability was admitted for the heterogeneous magnetic catalyst; no significant reduction of catalytic activity was observed even after five consecutive reaction cycles.
Zn(OAc)2·2H2O-catalyzed one-pot efficient synthesis of α-amino nitriles
Reddy, V. Venkata Rami,Saritha,Ramu,Varala, Ravi,Jayashree
, p. 7439 - 7442 (2015/04/22)
A mild, efficient one-pot three component strecker reaction involving electronically and structurally divergent aldehydes, amines and trimethly silyl cyanide in chloroform as solvent at room temperature was accomplished in moderate to excellent yields using an inexpensive and readily available catalyst, Zn(OAc)2.2H2O.
Sulfated tungstate: A green catalyst for Strecker reaction
Pathare, Sagar P.,Akamanchi, Krishnacharya G.
experimental part, p. 871 - 875 (2012/03/08)
A straightforward, mild, efficient, and general method has been developed for the synthesis of α-aminonitriles via Strecker reaction starting from aldehydes or ketones, amines, and trimethylsilyl cyanide in the presence of sulfated tungstate as a heterogeneous mild solid acid catalyst at room temperature and solvent free condition. The developed method has been successfully applied for the synthesis of a wide range of α-aminonitriles with variable functionality.
Sulfamic acid-functionalized magnetic Fe3O4 nanoparticles as an efficient and reusable catalyst for one-pot synthesis of α-amino nitriles in water
Kassaee,Masrouri, Hassan,Movahedi, Farnaz
experimental part, p. 28 - 33 (2012/01/04)
Grafting of chlorosulfuric acid on the amino-functionalized Fe 3O4 nanoparticles afforded sulfamic acid-functionalized magnetic Fe3O4 nanoparticles (SA-MNPs) as a novel organic-inorganic hybrid heterogeneous catalyst, which was characterized by XRD, FT-IR, TGA, TEM, and elemental analysis. The catalytic activity of SA-MNPs was probed through one-pot synthesis of α-amino nitriles via three-component couplings of aldehydes (or ketones), amines and trimethylsilyl cyanide in water, at room temperature. The heterogeneous catalyst could be recovered easily and reused many times without significant loss of its catalytic activity.
Ga-TUD-1: A new heterogeneous mesoporous catalyst for the solventless expeditious synthesis of α-aminonitriles
Karmakar, Bikash,Sinhamahapatra, Apurba,Panda, Asit Baran,Banerji, Julie,Chowdhury, Biswajit
experimental part, p. 111 - 117 (2011/10/13)
The high surface area three-dimensional porous catalyst has been prepared and characterized by TEM, BET S.A, low angle XRD, 29Si MAS NMR, NH3 TPD techniques. A simple, efficient and rapid method for the green synthesis of α-aminonitriles has been demonstrated over a new mesoporous gallosilicate catalyst Ga-TUD-1. The solventless technique has been applied for the synthesis of a range of compounds with variable functionality with excellent yield and selectivity. The catalyst has been recycled four times with reproducible yield.
Lewis base-catalyzed three-component Strecker reaction on water. An efficient manifold for the direct α-cyanoamination of ketones and aldehydes
Cruz-Acosta, Fabio,Santos-Exposito, Alicia,De Armas, Pedro,Garcia-Tellado, Fernando
experimental part, p. 6839 - 6841 (2010/03/25)
The first three-component organocatalyzed Strecker reaction operating on water has been developed. The manifold utilizes ketones (aldehydes) as the starting carbonyl component, aniline as the primary amine, acetyl cyanide as the cyanide source and N,N-dim
Strecker-type reaction catalyzed by carboxylic acids in aqueous media
Xie, Zhengfeng,Li, Guilong,Zhao, Gang,Wang, Jide
experimental part, p. 2035 - 2039 (2009/12/27)
Carboxylic acid catalyzed Strecker-type reactions were successfully carried out by simply mixing aldehydes, amines, tributyltin cyanide and carboxylic acid in aqueous media at room temperature, to afford α-aminonitriles in high yields. Georg Thieme Verlag
