1186-70-5

Basic information

• Product Name: METHOXY-BIS(DIMETHYLAMINO)METHANE
• Synonyms: Bis(dimethylamino)methoxymethane technical;DIMETHYLFORMAMIDE DIMETHYLACETALE AND TRIS(DIMETHYLAMINO)METHANE;METHOXY-BIS(DIMETHYLAMINO)METHANE;Bis(dimethylamino)methoxymethane;1-methoxy-N,N,N',N'-tetramethylmethylenediamine;methoxy-bis(dimethylamino)methanetech;dimethylformamide dimethyl acetal + tris(dimethylamino)methane;α-Methoxy-N,N,N',N'-tetramethylmethanediamine
• CAS NO: 1186-70-5
• Molecular Formula: C₆H₁₆N₂O
• Molecular Weight: 132.2
• EINECS: 214-695-5
• Mol File: 1186-70-5.mol

Chemical Properties

• Boiling Point: 120-125 °C(lit.)
• Flash Point: 14℃
• Appearance: /
• Density: 0.863 g/mL at 20 °C(lit.)
• Vapor Pressure: 18.8mmHg at 25°C
• Refractive Index: n20/D 1.418
• Storage Temp.: 2-8°C
• BRN: 1900972
• CAS DataBase Reference: METHOXY-BIS(DIMETHYLAMINO)METHANE(CAS DataBase Reference)
• NIST Chemistry Reference: METHOXY-BIS(DIMETHYLAMINO)METHANE(1186-70-5)
• EPA Substance Registry System: METHOXY-BIS(DIMETHYLAMINO)METHANE(1186-70-5)

Safety Data

• Hazard Codes: F
• Statements: 11
• RIDADR: UN 1993 3/PG 2
• WGK Germany: 3
• HazardClass: 3.1
• PackingGroup: II
• Hazardous Substances Data: 1186-70-5(Hazardous Substances Data)

Usage

Uses

Used in Research and Development:
Methoxy-bis(dimethylamino)methane is used as a research chemical for [application reason] in the scientific community. Its unique properties make it valuable for exploring various chemical reactions and processes, contributing to the advancement of chemical knowledge and potential applications in specialized fields.
Used in Chemical Synthesis:
In the chemical synthesis industry, Methoxy-bis(dimethylamino)methane is used as a reagent or intermediate for [application reason] in the production of other organic compounds. Its specific chemical structure allows it to participate in various reactions, facilitating the synthesis of target molecules.
Used in Laboratory Settings:
Methoxy-bis(dimethylamino)methane is used as a laboratory chemical for [application reason] in academic and industrial research labs. Its controlled environment use ensures safety and allows for precise experimentation, leading to a better understanding of its properties and potential applications.

InChI:InChI=1/C6H16N2O/c1-7(2)6(9-5)8(3)4/h6H,1-5H3

Upstream product

• 2214-82-6 Bis(dimethylamino)acetonitrile 
• 124-41-4 sodium methylate 
• 2013-91-4 N,N,N',N'-tetramethylformamidinium methyl sulfate 
• 110-91-8 morpholine 
• 4637-24-5 N,N-dimethyl-formamide dimethyl acetal 
• 67-56-1 methanol 
• 119522-06-4 Di-tert-butylphosphine 
• 124-40-3 dimethyl amine 
• 1071-38-1 N,N,N',N'-Tetramethylformamidinium chloride 

Downstream Products

• 1201-93-0 1-phenyl-3-dimethylaminoprop-2-enone 
• 1187-27-5 2-cyano-3-dimethylamino acrylate 
• 76344-78-0 ethyl 3-(N,N-dimethylamino)-2-(p-methoxyphenyl)propenoate 
• 117121-19-4 N,N-bis(3-amino-1-methoxy-1-oxo-2-propen-2-yl)phenylamine 
• 84590-77-2 4-phenyl-5H-pyrido<3,4-b><1,4>benzothiazin-3-2H-one 
• 84590-76-1 4-(4-chlorophenyl)-5H-pyrido<3,4-b><1,4>benzothiazin-3-2H-one 
• 62502-14-1 3-(3,4-methylenedioxyphenyl)-8,8-dimethyl-4-oxo-4H,8H-benzo[1,2-b:3,4-b']dipyran 
• 84590-81-8 4-(2-fluorophenyl)-5H-pyrido<3,4-b><1,4>benzothiazin-3-2H-one 
• 84590-78-3 4-(2-chlorophenyl)-5H-pyrido<3,4-b><1,4>benzothiazin-3-2H-one 
• 84590-79-4 4-<(3-trifluoromethyl)phenyl>-5H-pyrido<3,4-b><1,4>benzothiazin-3-2H-one 
• 66380-92-5 1-(3-benzyloxy-4-methoxyphenyl)-5-dimethylamino-1,4-pentadien-3-one 
• 632-22-4 tetramethylurea 
• 90-29-9 7-hydroxy-3',4'-methylenedioxyisoflavone 
• 24211-36-7 AnCoA₄ 

Relevant articles and documents

1H Nuclear Magnetic Resonance Study of the Kinetics of the Reaction of N,N-Dialkylformamide Dimethyl Acetals with Secondary Amines

Rate constants and activation parameters (ΔG, ΔH, ΔS) for the reactions of N,N-dialkylformamide dimethyl acetals with four secondary amines have been estimated by 1H n.m.r. spectroscopy.The reactions are reversible and obey a second-order kinetic equation.Substitution of one methoxy group of the amide acetal by the amine entity is found to give ester aminals which are subject to decomposition (ΔG 92-103 kJ mol-1).A transamination reaction yields a new amide acetal at higher temperatures (ΔG 115 kJ mol-1).On the basis of the kinetic data, the mechanism of these reactions is discussed.

Bredereck's reagent revisited: Latent anionic ring-opening polymerization and transesterification reactions

The ring-opening polymerization of lactide with commercially available Bredereck-type reagents in the presence or absence of alcohol initiators was carried out affording polylactide with controlled molecular weight and narrow polydispersities. An anionic mechanism involving heterolytic cleavage to alkoxides is proposed, where these reagents function as latent anionic initiators for the ring-opening polymerization of lactide.

Preparation of 1-nitroanthraquinone-2-carboxylic acid

1-Nitroanthraquinone-2-carboxylic acid of the formula I STR1 is prepared by treating novel 2-substituted 1-nitroanthraquinones of the general formula II STR2 where R is --CH=CH--R1 or --CH2 --CHO, where R1 is C1 -C5 -dialkylamino or a cyclic 5- or 6-membered amine which may contain further hetero atoms, with oxidizing agents free of heavy metal.

1H and 13C Nuclear Magnetic Resonance Identification of the Products of the Reaction of NN-Dialkylformamide Dimethyl Acetals with Secondary Amines

Eight reactions of NN-dialkylformamide dimethyl acetals with secondary amines have been followed by means of 1H n.m.r.The reaction products were not only other amide acetals but also ester aminals and orthoamides.Therefore secondary amines exchanged the amine moiety and the methoxy group of the amide acetal.The relative concentrations of products at equilibrium have been estimated.The 13C chemical shifts for substrates and some products have been reported.

Reaction of Singlet Oxygen with Enamino Carbonyl Systems. A General Method for the Synthesis of α-Keto Derivatives of Lactones, Esters, Amides, Lactams, and Ketones

A general method for the introduction of a ketone α to the carbonyl group of a ketone, lactone. ester, substituted amide, or lactam has been developed involving the formation and dye-sensitized photooxygenation of enamino carbonyl intermediates.