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1259603-82-1

(S)-1-(imidazo[1,2-a]pyridin-6-yl)ethan-1-amine is a chemical compound belonging to the imidazo[1,2-a]pyridine family, characterized by the molecular formula C11H13N3. It features an amine functional group and holds potential pharmacological activities, particularly in medicinal chemistry. (S)-1-(imidazo[1,2-a]pyridin-6-yl)ethan-1-amine is of interest due to its possible applications in the development of therapeutic agents for central nervous system disorders, given the known studies on related imidazo[1,2-a]pyridine derivatives.

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  • 1259603-82-1 Structure

  • Basic information

    1. Product Name: (S)-1-(imidazo[1,2-a]pyridin-6-yl)ethan-1-amine
    2. Synonyms: (S)-1-(imidazo[1,2-a]pyridin-6-yl)ethan-1-amine;(1S)-1-imidazo[1,2-a]pyridin-6-ylethanamine,hydrochloride;(1S)-1-(4-HYDROIMIDAZO[1,2-A]PYRIDIN-6-YL)ETHYLAMINE HCl;EOS-60800
    3. CAS NO:1259603-82-1
    4. Molecular Formula: C9H11N3
    5. Molecular Weight: 161.20374
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 1259603-82-1.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: 1.22±0.1 g/cm3(Predicted)
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. PKA: 8.31±0.29(Predicted)
    10. CAS DataBase Reference: (S)-1-(imidazo[1,2-a]pyridin-6-yl)ethan-1-amine(CAS DataBase Reference)
    11. NIST Chemistry Reference: (S)-1-(imidazo[1,2-a]pyridin-6-yl)ethan-1-amine(1259603-82-1)
    12. EPA Substance Registry System: (S)-1-(imidazo[1,2-a]pyridin-6-yl)ethan-1-amine(1259603-82-1)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 1259603-82-1(Hazardous Substances Data)

1259603-82-1 Usage

Uses

Used in Pharmaceutical Industry:
(S)-1-(imidazo[1,2-a]pyridin-6-yl)ethan-1-amine is used as a compound of interest for drug development, specifically targeting central nervous system disorders. Its unique structure and properties make it a valuable candidate for further investigation and potential use in creating novel therapeutic agents.
Used in Medicinal Chemistry Research:
In the field of medicinal chemistry, (S)-1-(imidazo[1,2-a]pyridin-6-yl)ethan-1-amine serves as a key compound for research purposes. Its potential pharmacological activities and the possibility of its application in treating neurological diseases make it an important subject for scientific exploration and experimentation.

Check Digit Verification of cas no

The CAS Registry Mumber 1259603-82-1 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,5,9,6,0 and 3 respectively; the second part has 2 digits, 8 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 1259603-82:
(9*1)+(8*2)+(7*5)+(6*9)+(5*6)+(4*0)+(3*3)+(2*8)+(1*2)=171
171 % 10 = 1
So 1259603-82-1 is a valid CAS Registry Number.

1259603-82-1SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name (1S)-1-imidazo[1,2-a]pyridin-6-ylethanamine,hydrochloride

1.2 Other means of identification

Product number -
Other names EX-5984

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:1259603-82-1 SDS

1259603-82-1Relevant articles and documents

IMPROVED METHOD FOR THE MANUFACTURE OF 3-[(1S)-1-IMIDAZO[1,2-A]PYRIDIN-6-YLETHYL]-5-(1-METHYLPYRAZOL-4-YL)TRIAZOLO[4,5-B]PYRAZINE AND POLYMORPHIC FORMS THEREOF

-

, (2020/05/07)

This specification generally relates to an improved method for the manufacture of 3-[(lS)-l -imidazo[ 1,2-a]pyridin-6-ylethyl]-5-(l-methylpyrazol-4-yl)triazolo[4,5- bjpyrazine (I), or pharmaceutically acceptable salts thereof; polymorphic forms thereof; and intermediates useful in the manufacture of such compounds and salts thereof. Formula (I).

Discovery of (S)-1-(1-(Imidazo[1,2- a ]pyridin-6-yl)ethyl)-6-(1-methyl-1 H -pyrazol-4-yl)-1 H -[1,2,3]triazolo[4,5- b ]pyrazine (Volitinib) as a Highly Potent and Selective Mesenchymal-Epithelial Transition Factor (c-Met) Inhibitor in Clinical Development for Treatment of Cancer

Jia, Hong,Dai, Guangxiu,Weng, Jianyang,Zhang, Zhulin,Wang, Qing,Zhou, Feng,Jiao, Longxian,Cui, Yumin,Ren, Yongxin,Fan, Shiming,Zhou, Jinghong,Qing, Weiguo,Gu, Yi,Wang, Jian,Sai, Yang,Su, Weiguo

supporting information, p. 7577 - 7589 (2014/12/11)

HGF/c-Met signaling has been implicated in human cancers. Herein we describe the invention of a series of novel triazolopyrazine c-Met inhibitors. The structure-activity relationship of these compounds was investigated, leading to the identification of compound 28, which demonstrated favorable pharmacokinetic properties in mice and good antitumor activities in the human glioma xenograft model in athymic nude mice.

CERTAIN TRIAZOLOPYRIDINES AND TRIAZOLOPYRAZINES, COMPOSITIONS THEREOF AND METHODS OF USE THEREFOR

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Page/Page column 28, (2012/10/08)

Provided are certain triazolopyridines and triazolopyrazines, compositions thereof and methods of use therefor.

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