128660-97-9

Basic information

• Product Name: THP-PEG5
• Synonyms: THP-PEG5;THP-PEG4-alcohol
• CAS NO: 128660-97-9
• Molecular Formula: C₁₃H₂₆O₆
• Molecular Weight: 278.34194
• Mol File: 128660-97-9.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: THP-PEG5(CAS DataBase Reference)
• NIST Chemistry Reference: THP-PEG5(128660-97-9)
• EPA Substance Registry System: THP-PEG5(128660-97-9)

Safety Data

• Hazardous Substances Data: 128660-97-9(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
THP-PEG5 is used as a protecting group for alcohols in the synthesis of complex organic molecules, particularly in the pharmaceutical industry. The acid-labile nature of the THP group allows for selective deprotection under acidic conditions, enabling the controlled release of active pharmaceutical ingredients.
Used in Drug Delivery Systems:
THP-PEG5 is used as a component in the design and development of drug delivery systems. The hydrophilic PEG linkers improve the solubility and stability of drug molecules in aqueous environments, while the terminal hydroxyl group allows for the attachment of drug molecules or other functional groups. This enhances the bioavailability and targeted delivery of therapeutic agents.
Used in Chemical Synthesis:
THP-PEG5 is used as an intermediate in the synthesis of various chemical compounds, particularly those requiring a hydroxyl group for further functionalization. The acid-labile THP group provides a means to control the reactivity and selectivity of the molecule during the synthesis process.
Used in Bioconjugation:
THP-PEG5 is used as a bioconjugation agent, facilitating the attachment of biologically active molecules, such as proteins, peptides, or nucleic acids, to other molecules or surfaces. The hydroxyl group can be used to form covalent bonds with the target biomolecule, while the PEG linker provides a hydrophilic spacer to reduce non-specific interactions and increase solubility.
Used in Material Science:
THP-PEG5 can be used in the development of novel materials with enhanced properties, such as improved water solubility, increased stability, or tailored reactivity. The PEG linker and terminal hydroxyl group can be incorporated into polymers, dendrimers, or other macromolecular structures to achieve specific material characteristics.

Upstream product

• 110-87-2 3,4-dihydro-2H-pyran 
• 112-60-7 Tetraethylene glycol 

Downstream Products

• 86259-87-2 1-phenyl-2,5,8,11-tetraoxatridecan-13-ol 
• 1611489-00-9 monotetrahydropyranyl octa(ethylene glycol) monobenzyl ether 
• 477775-73-8 1-phenyl-2,5,8,11,14,17,20,23-octaoxapenta-cosan-25-ol 
• 130955-37-2 2-(2-(2-(2-hydroxyethoxy)ethoxy)ethyl) methanesulfonate 
• 23783-42-8 tetraethylene glycol monomethyl ether 
• 1429426-19-6 C₆₁H₆₇N₃O₈P₂Pt 
• 1429426-21-0 C₄₇H₅₉Cl₂NO₈P₂Pt 
• 1429426-20-9 2,6-bis(13-(diphenylphosphino)-2,5,8,11-tetraoxatridecyl)pyridine 
• 1416729-01-5 C₃₇H₄₉NO₁₂ 
• 1416729-04-8 C₅₃H₆₅N₅O₁₀ 
• 187600-67-5 14-[[(4-methylphenyl)sulfonyl]oxy]-3,6,9,12-tetraoxatetradecanoic acid phenylmethyl ester 
• 195071-47-7 14-hydroxy-3,6,9,12-tetraoxatetradecanoic acid phenylmethyl ester 
• 1318760-40-5 3,6,9,12-tetraoxatetradecanoic acid 14-[[tetrahydro-2H-pyran-2-yl]oxy]phenylmethyl ester 

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