131501-59-2Relevant articles and documents
Discrimination in metal-ion binding to RNA dinucleotides with a non-bridging oxygen or sulfur in the phosphate diester link
Knobloch, Bernd,Nawrot, Barbara,Okruszek, Andrzej,Sigel, Roland K.O.
supporting information; scheme or table, p. 3100 - 3109 (2009/04/16)
Replacement of a non-bridging oxygen in the phosphate diester bond by a sulfur has become quite popular in nucleic acid research and is often used as a probe, for example, in ribozymes, where the normally essential Mg2+ is partly replaced by a
Acid-base and metal-ion binding properties of the RNA dinucleotide uridylyl-(5′→3′)-[5′]uridylate (pUpU3-)
Knobloch, Bernd,Suliga, Danuta,Okruszek, Andrzej,Sigel, Roland K.O.
, p. 4163 - 4170 (2007/10/03)
It is well known that Mg2+ and other divalent metal ions bind to the phosphate groups of nucleic acids. Subtle differences in the coordination properties of these metal ions to RNA, especially to ribozymes, determine whether they either promote