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2-Bromo-6-fluoro-3-methylbenzoic acid, an organic compound with the molecular formula C8H6BrFO2, is a derivative of benzoic acid. It features a bromine atom at the 2nd position, a fluorine atom at the 6th position, and a methyl group at the 3rd position. 2-broMo-6-fluoro-3-Methylbenzoic acid is known for its potential applications in pharmaceuticals and organic synthesis, serving as a building block for the creation of biologically active molecules. Its unique structure, with both bromine and fluorine atoms, makes it a promising candidate for research in medicinal chemistry and drug development, as well as for its antimicrobial and antiproliferative properties.

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  • 1359857-60-5 Structure
  • Basic information

    1. Product Name: 2-broMo-6-fluoro-3-Methylbenzoic acid
    2. Synonyms: 2-broMo-6-fluoro-3-Methylbenzoic acid;6-Bromo-2-fluoro-5-methylbenzoic acid
    3. CAS NO:1359857-60-5
    4. Molecular Formula: C8H6BrFO2
    5. Molecular Weight: 233.0344432
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 1359857-60-5.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: 2-8°C
    8. Solubility: N/A
    9. CAS DataBase Reference: 2-broMo-6-fluoro-3-Methylbenzoic acid(CAS DataBase Reference)
    10. NIST Chemistry Reference: 2-broMo-6-fluoro-3-Methylbenzoic acid(1359857-60-5)
    11. EPA Substance Registry System: 2-broMo-6-fluoro-3-Methylbenzoic acid(1359857-60-5)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 1359857-60-5(Hazardous Substances Data)

1359857-60-5 Usage

Uses

Used in Pharmaceutical Industry:
2-Bromo-6-fluoro-3-methylbenzoic acid is used as a building block for the synthesis of various biologically active molecules, contributing to the development of new drugs and therapeutic agents. Its presence in the pharmaceutical industry is due to its potential to be incorporated into molecules with specific pharmacological properties, enhancing their efficacy and selectivity.
Used in Organic Synthesis:
In the field of organic synthesis, 2-bromo-6-fluoro-3-methylbenzoic acid is utilized as a key intermediate for the preparation of complex organic compounds. Its unique functional groups and structural features make it a valuable component in the synthesis of a wide range of organic molecules, including pharmaceuticals, agrochemicals, and other specialty chemicals.
Used in Medicinal Chemistry Research:
2-Bromo-6-fluoro-3-methylbenzoic acid is employed as a subject of study in medicinal chemistry research, where its properties and potential applications are explored. The presence of both bromine and fluorine atoms in its structure makes it an interesting candidate for the development of new drugs and therapeutic agents, as these elements can significantly influence the pharmacokinetic and pharmacodynamic properties of molecules.
Used in Drug Development:
In drug development, 2-bromo-6-fluoro-3-methylbenzoic acid is used as a starting material or a precursor for the synthesis of novel drug candidates. Its unique structural features and potential antimicrobial and antiproliferative properties make it a valuable compound for the development of new therapeutic agents, particularly in the treatment of infectious diseases and cancer.
Used in Antimicrobial Applications:
2-Bromo-6-fluoro-3-methylbenzoic acid is studied for its potential antimicrobial properties, making it a candidate for the development of new antimicrobial agents. Its ability to inhibit the growth of various microorganisms could lead to the creation of new treatments for bacterial and fungal infections.
Used in Antiproliferative Applications:
2-broMo-6-fluoro-3-Methylbenzoic acid is also investigated for its antiproliferative properties, which could be harnessed in the development of anticancer drugs. By inhibiting the proliferation of cancer cells, 2-bromo-6-fluoro-3-methylbenzoic acid may contribute to the discovery of new therapeutic options for the treatment of various types of cancer.

Check Digit Verification of cas no

The CAS Registry Mumber 1359857-60-5 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,3,5,9,8,5 and 7 respectively; the second part has 2 digits, 6 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 1359857-60:
(9*1)+(8*3)+(7*5)+(6*9)+(5*8)+(4*5)+(3*7)+(2*6)+(1*0)=215
215 % 10 = 5
So 1359857-60-5 is a valid CAS Registry Number.

1359857-60-5SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-Bromo-6-fluoro-3-methylbenzoic acid

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:1359857-60-5 SDS

1359857-60-5Relevant articles and documents

QUINOXALINE DERIVATIVES

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, (2021/07/24)

The present invention relates to compounds according to general formula (I), which act as modulators of the glucocorticoid receptor and can be used in the treatment and/or prophylaxis of disorders which are at least partially mediated by the glucocorticoid receptor.

ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES

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Paragraph 0167, (2019/02/25)

A compound having a structure of the formula Ir(LA)(LB), in which LA is a bidentate, tridentate, tetradentate, pentadentate, or hexadentate ligand and LB is a monodentate, bidentate, tridentate, or tetradentate ligand, or not present, and where the total denticity of LA plus LB is 6, and LA includes at least one structure of Formula I: is disclosed as a useful phosphorescent emitter compound.

1 -HYDROXY-BENZOOXABOROLES AS ANTIPARASITIC AGENTS

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, (2014/10/03)

Provided are compounds useful for controlling endoparasites both in animals and agriculture. Further provided are methods for controlling endoparasite infestations of an animal by administering an effective amount of a compound as described above, or a pharmaceutically acceptable salt thereof, to an animal, as well as formulations for controlling endoparasite infestations using the compounds described above or an acceptable salt thereof, and an acceptable carrier. The claimed compounds are described by the following Markush formula:A typical example for a compound according to above formula is: A typical example for a compound according to above formula is:

Benzoxaborole antimalarial agents. Part 2: Discovery of fluoro-substituted 7-(2-carboxyethyl)-1,3-dihydro-1-hydroxy-2,1-benzoxaboroles

Zhang, Yong-Kang,Plattner, Jacob J.,Freund, Yvonne R.,Easom, Eric E.,Zhou, Yasheen,Ye, Long,Zhou, Huchen,Waterson, David,Gamo, Francisco-Javier,Sanz, Laura M.,Ge, Min,Li, Zhiya,Li, Lingchao,Wang, Hailong,Cui, Han

, p. 1299 - 1307 (2012/03/26)

A series of new boron-containing benzoxaborole compounds was designed and synthesized for a continuing structure-activity relationship (SAR) investigation to assess the antimalarial activity changes derived from side-chain structural variation, substituent modification on the benzene ring and removal of boron from five-membered oxaborole ring. This SAR study demonstrated that boron is required for the antimalarial activity, and discovered that three fluoro-substituted 7-(2-carboxyethyl)-1,3-dihydro-1-hydroxy-2,1-benzoxaboroles (9, 14 and 20) have excellent potencies (IC50 0.026-0.209 μM) against Plasmodium falciparum.

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