1426151-00-9

Basic information

• Product Name: Maleimide-PEG12-NH
• Synonyms: 2,5-Dioxopyrrolidin-1-yl 1-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)-3-oxo-7,10,13,16,19,22,25,28,31,34,37,40-dodecaoxa-4-azatritetracontan-43-oate;2,5-Dioxopyrrolidin-1-yl-1-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)-3-oxo-7,10,13,16,19,22,25,28,31,34,37,40-dodecaoxa-4-azatritetracontan-43-oate;Maleimide PEG12 succinimidyl ester;Maleimide-PEG12-NH;Maleimide-PEG12-succinimidyl ester
• CAS NO: 1426151-00-9
• Molecular Formula: C38H63N3O19
• Molecular Weight: 865.91552
• Mol File: 1426151-00-9.mol

Chemical Properties

• Appearance: /
• Storage Temp.: ?20°C
• CAS DataBase Reference: Maleimide-PEG12-NH(CAS DataBase Reference)
• NIST Chemistry Reference: Maleimide-PEG12-NH(1426151-00-9)
• EPA Substance Registry System: Maleimide-PEG12-NH(1426151-00-9)

Safety Data

• WGK Germany: 3
• Hazardous Substances Data: 1426151-00-9(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical and Biomedical Applications:
Maleimide-PEG12-NH is used as a crosslinking agent for the conjugation of drugs, targeting moieties, or imaging agents to biomolecules such as proteins, peptides, and antibodies. This allows for the development of targeted drug delivery systems, improved pharmacokinetics, and enhanced therapeutic efficacy.
Used in Bioconjugation and Protein Engineering:
In the field of bioconjugation and protein engineering, Maleimide-PEG12-NH is used as a coupling agent to modify proteins and other biomolecules with specific functional groups. This enables the creation of novel bioconjugates with tailored properties, such as improved stability, solubility, or bioactivity.
Used in Research and Development:
Maleimide-PEG12-NH is utilized as a research tool for the study of protein-protein interactions, enzyme kinetics, and the development of new bioanalytical methods. Its ability to selectively react with specific functional groups allows for the precise manipulation of biomolecules in various experimental setups.
Used in Diagnostics:
In the diagnostics industry, Maleimide-PEG12-NH is employed as a component in the development of immunoassays, biosensors, and other diagnostic tools. Its unique reactivity with sulfhydryl-containing compounds enables the creation of highly specific and sensitive detection systems for various analytes.
Overall, Maleimide-PEG12-NH is a versatile and valuable compound with a wide range of applications in the pharmaceutical, biomedical, research, and diagnostics industries, thanks to its ability to selectively crosslink amineand sulfhydryl-containing compounds or biomolecules.

Upstream product

• 6066-82-6 1-hydroxy-pyrrolidine-2,5-dione 
• 756525-98-1 3-(2-{2-[3-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)propanamido]ethoxy}ethoxy)propanoic acid 
• 7423-55-4 3-maleimidepropionic acid 
• 121215-45-0 3-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)propanoyl chloride 
• 2055353-75-6 C₁₆H₂₄N₂O₈ 
• 55750-62-4 3-maleimidopropionic acid N-hydroxysuccinimide ester 
• 1263045-16-4 1-[3-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)propanamido]-3,6,9,12-tetraoxapentadecan-15-oic acid 
• 1615234-93-9 14-carboxy-3,6,9,12-tetraoxatetradecan-1-ammonium 2,2,2-trifluoroacetate 
• 756525-91-4 3-[2-[2-[2-[2-(tert-butoxycarbonylamino)ethoxy]ethoxy]ethoxy]ethoxy]propanoic acid 

Downstream Products

• 932744-55-3 C₃₈H₅₈N₈O₁₃ 

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