756525-91-4

Usage

Uses

Used in Pharmaceutical Industry:
BOC-15-AMINO-4,7,10,13-TETRAOXAPENTADECANOIC ACID is used as a substitution variant of cocaine esterase for improved stability. This application is crucial for the treatment of cocaine overdose, as it helps in the rapid metabolism and detoxification of the drug, reducing its harmful effects on the body.

Synthetic route

benzyl (E)-2,2-dimethyl-4-oxo-3,8,11,14,17-pentaoxa-5-azaicos-18-en-20-oate → 3-[2-[2-[2-[2-(tert-butoxycarbonylamino)ethoxy]ethoxy]ethoxy]ethoxy]propanoic acid (756525-91-4)

Conditions	Yield
With palladium 10% on activated carbon; hydrogen In tetrahydrofuran under 760.051 Torr; for 24h;	100%

3-[2-(2-{2-[2-(2-aminoethoxy)ethoxy]ethoxy}ethoxy)ethoxy]propanoic acid (663921-15-1) + di-tert-butyl dicarbonate (24424-99-5) → 3-[2-[2-[2-[2-(tert-butoxycarbonylamino)ethoxy]ethoxy]ethoxy]ethoxy]propanoic acid (756525-91-4)

Conditions	Yield
With potassium carbonate In tetrahydrofuran; water at 20℃; Cooling with ice;	93%

2-<2-<2-<2-<(tert-Butoxycarbonyl)amino>ethoxy>ethoxy>ethoxy>ethanol (106984-09-2) → 3-[2-[2-[2-[2-(tert-butoxycarbonylamino)ethoxy]ethoxy]ethoxy]ethoxy]propanoic acid (756525-91-4)

Conditions	Yield
Multi-step reaction with 2 steps 1: 4-methyl-morpholine / dichloromethane / 18 h / 20 °C 2: palladium 10% on activated carbon; hydrogen / tetrahydrofuran / 24 h / 760.05 Torr View Scheme

3-[2-[2-[2-[2-(tert-butoxycarbonylamino)ethoxy]ethoxy]ethoxy]ethoxy]propanoic acid (756525-91-4) + C19H22ClN5*2C2HF3O2 → C35H51ClN6O7

Conditions	Yield
With N-ethyl-N,N-diisopropylamine; N-[(dimethylamino)-3-oxo-1H-1,2,3-triazolo[4,5-b]pyridin-1-yl-methylene]-N-methylmethanaminium hexafluorophosphate In N,N-dimethyl-formamide at 22℃; for 1.5h;	100%

3-[2-[2-[2-[2-(tert-butoxycarbonylamino)ethoxy]ethoxy]ethoxy]ethoxy]propanoic acid (756525-91-4) + C19H25N5S → C35H54N6O7S

Conditions	Yield
With N-[(dimethylamino)-3-oxo-1H-1,2,3-triazolo[4,5-b]pyridin-1-yl-methylene]-N-methylmethanaminium hexafluorophosphate In N,N-dimethyl-formamide at 22℃; for 3h;	100%

3-[2-[2-[2-[2-(tert-butoxycarbonylamino)ethoxy]ethoxy]ethoxy]ethoxy]propanoic acid (756525-91-4) + C20H24ClN5*C2HF3O2 → C36H53ClN6O7

Conditions	Yield
With N-[(dimethylamino)-3-oxo-1H-1,2,3-triazolo[4,5-b]pyridin-1-yl-methylene]-N-methylmethanaminium hexafluorophosphate In N,N-dimethyl-formamide at 22℃; for 1h;	100%

3-[2-[2-[2-[2-(tert-butoxycarbonylamino)ethoxy]ethoxy]ethoxy]ethoxy]propanoic acid (756525-91-4) + (S)-4,11-diethyl-4-hydroxy-3,14-dioxo-3,4,12,14-tetrahydro-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinolin-9-yl piperazine-1-carboxylate (97682-37-6) → (S)-4,11-diethyl-4-hydroxy-3,14-dioxo-3,4,12,14-tetrahydro-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinolin-9-yl 4-[3-[2-[2-[2-[2-(tert-butoxycarbonylamino)ethoxy]ethoxy]ethoxy]ethoxy]propanoyl]piperazine-1-carboxylate

Conditions	Yield
With (benzotriazo-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate; triethylamine In dichloromethane at 20℃; for 24h;	99%

3-[2-[2-[2-[2-(tert-butoxycarbonylamino)ethoxy]ethoxy]ethoxy]ethoxy]propanoic acid (756525-91-4) + rac-tyrosine benzyl ester p-toluenesulfonate → t-boc-NH-dPEG4-CO-Tyr-OBn

Conditions	Yield
With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine In dichloromethane at 5 - 20℃;	98%

3-[2-[2-[2-[2-(tert-butoxycarbonylamino)ethoxy]ethoxy]ethoxy]ethoxy]propanoic acid (756525-91-4) + 4,11-diethyl-4-hydroxy-3,14-dioxo-3,4,12,14-tetrahydro-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinolin-9-yl (S)-4-(aminomethyl)cyclohexanecarboxylate → (S)-4,11-diethyl-4-hydroxy-3,14-dioxo-3,4,12,14-tetrahydro-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinolin-9-yl 4-(21,21-dimethyl-3,19-dioxo-6,9,12,15,20-pentaoxa-2,18-diazadocosyl)cyclohexanecarboxylate

Conditions	Yield
With (benzotriazo-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate; triethylamine In dichloromethane at 20℃; for 24h;	96%

1-hydroxy-pyrrolidine-2,5-dione (6066-82-6) + 3-[2-[2-[2-[2-(tert-butoxycarbonylamino)ethoxy]ethoxy]ethoxy]ethoxy]propanoic acid (756525-91-4) → 2,5-dioxopyrrolidin-1-yl 2,2-dimethyl-4-oxo-3,8,11,14,17-pentaoxa-5-azaicosan-20-oate

Conditions	Yield
With 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In dichloromethane at 20℃; for 18h;	94%
With dicyclohexyl-carbodiimide In dichloromethane
With dicyclohexyl-carbodiimide In dichloromethane at 0 - 20℃; for 2h;
With dicyclohexyl-carbodiimide In dichloromethane at 20℃;
With 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In dichloromethane at 20℃;

3-[2-[2-[2-[2-(tert-butoxycarbonylamino)ethoxy]ethoxy]ethoxy]ethoxy]propanoic acid (756525-91-4) + (2S,4R)-1-[(2S)-2-azanyl-3,3-dimethylbutanoyl]-N-[[4-(4-methyl-1,3-thiazol-5-yl)phenyl]methyl]-4-oxidanylpyrrolidine-2-carboxamide (1448297-52-6) → tert-butyl ((S)-17-((2S,4R)-4-hydroxy-2-((4-(4-methylthiazol-5-yl)benzyl)carbamoyl)pyrrolidine-1-carbonyl)-18,18-dimethyl-15-oxo-3,6,9,12-tetraoxa-16-azanonadecyl)carbamate

Conditions	Yield
With N-[(dimethylamino)-1H-1,2,3-triazolo[4,5-b]pyridine-1-ylmethylene]-N-methylmethanaminium hexafluorophosphate N-oxide; triethylamine In N,N-dimethyl-formamide at 20℃; Inert atmosphere;	92%

3-[2-[2-[2-[2-(tert-butoxycarbonylamino)ethoxy]ethoxy]ethoxy]ethoxy]propanoic acid (756525-91-4) → 1-amino-3,6,9,12-tetraoxapentadecan-15-oic acid hydrochloride

Conditions	Yield
With hydrogenchloride In 1,4-dioxane at 20℃; for 2h;	90%

3-[2-[2-[2-[2-(tert-butoxycarbonylamino)ethoxy]ethoxy]ethoxy]ethoxy]propanoic acid (756525-91-4) + Propargylamine → tert-butyl(15-oxo-3,6,9,12-tetraoxa-16-azanonadeca-18-yne-1-yl)carbamate

Conditions	Yield
With 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In dichloromethane at 20℃; for 3h;	89%
With 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In dichloromethane at 20℃;	72%
With 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In dichloromethane at 20℃; for 16h; Inert atmosphere;	71%
With 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In dichloromethane at 20℃; for 16h; Inert atmosphere;	71%
With 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In dichloromethane at 20℃; for 16h; Inert atmosphere;	71%

3-[2-[2-[2-[2-(tert-butoxycarbonylamino)ethoxy]ethoxy]ethoxy]ethoxy]propanoic acid (756525-91-4) + C20H23ClN4O → C36H52ClN5O8

Conditions	Yield
With N-ethyl-N,N-diisopropylamine; N-[(dimethylamino)-3-oxo-1H-1,2,3-triazolo[4,5-b]pyridin-1-yl-methylene]-N-methylmethanaminium hexafluorophosphate In N,N-dimethyl-formamide at 22℃; for 18h;	85%

3-[2-[2-[2-[2-(tert-butoxycarbonylamino)ethoxy]ethoxy]ethoxy]ethoxy]propanoic acid (756525-91-4) + (3-(5H,6H-11,12-didehydrodibenzo[b,f]azocin-5-yl)-3-oxopropyl)amine (1255942-06-3) → N-boc protected ADIBO-PEG4-amine (1255942-12-1)

Conditions	Yield
Stage #1: 3-[2-[2-[2-[2-(tert-butoxycarbonylamino)ethoxy]ethoxy]ethoxy]ethoxy]propanoic acid With 1,2-dichloro-ethane; N-ethyl-N,N-diisopropylamine In dichloromethane at 20℃; for 0.25h; Stage #2: N-(3-aminopropionyl)-5,6-dihydro-11,12-didehydrodibenzo[b,f]azocine In dichloromethane at 20℃; for 4h;	80%
Stage #1: 3-[2-[2-[2-[2-(tert-butoxycarbonylamino)ethoxy]ethoxy]ethoxy]ethoxy]propanoic acid With 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In dichloromethane at 20℃; for 0.25h; Stage #2: N-(3-aminopropionyl)-5,6-dihydro-11,12-didehydrodibenzo[b,f]azocine In dichloromethane for 4h;

N-(tert-butyloxycarbonyl)-S-methylisothiourea (173998-77-1) + 3-[2-[2-[2-[2-(tert-butoxycarbonylamino)ethoxy]ethoxy]ethoxy]ethoxy]propanoic acid (756525-91-4) → N-tert-butoxycarbonyl-N’-[15-(tert-butoxycarbonylamino-4,7,10,13-tetraoxa)pentadecanoyl]-S-methylisothiourea (1334181-91-7)

Conditions	Yield
With O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborate; benzotriazol-1-ol; N-ethyl-N,N-diisopropylamine In N,N-dimethyl-formamide at 20℃; for 16h;	80%
With benzotriazol-1-ol; O-(benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborate; N-ethyl-N,N-diisopropylamine In water; N,N-dimethyl-formamide at 20℃; for 16h;	80%

3-[2-[2-[2-[2-(tert-butoxycarbonylamino)ethoxy]ethoxy]ethoxy]ethoxy]propanoic acid (756525-91-4) + cholesterol (57-88-5) → cholest-5-en-3-yl 2,2-dimethyl-4-oxo-3,8,11,14,17-pentaoxa-5-azaicosan-20-oate (1147885-57-1)

Conditions	Yield
With dmap; diisopropyl-carbodiimide In dichloromethane at 20℃;	75%

3-[2-[2-[2-[2-(tert-butoxycarbonylamino)ethoxy]ethoxy]ethoxy]ethoxy]propanoic acid (756525-91-4) → tert-butyl {trans-4-[(3-{5-[(2S)-1-methylpyrrolidin-2-yl]pyridin-3-yl}propyl)carbamoyl]cyclohexyl}carbamate (1351946-91-2) + tert-butyl (19-{5-[(2S)-1-methylpyrrolidine-2-yl]pyridine-3-yl}-15-oxo-3,6,9,12-tetraoxa-16-azanonadeca1-yl)carbamate (1351946-92-3)

Conditions	Yield
	A n/a B 70%

Tau (107-35-7) + 3-[2-[2-[2-[2-(tert-butoxycarbonylamino)ethoxy]ethoxy]ethoxy]ethoxy]propanoic acid (756525-91-4) → 1-ammonio-15-oxo-3,6,9,12-tetraoxa-16-azaoctadecane-18-sulfonate

Conditions	Yield
Stage #1: 3-[2-[2-[2-[2-(tert-butoxycarbonylamino)ethoxy]ethoxy]ethoxy]ethoxy]propanoic acid With di(succinimido) carbonate; N-ethyl-N,N-diisopropylamine In tetrahydrofuran at 20℃; Inert atmosphere; Stage #2: Tau In tetrahydrofuran; water at 20℃;	70%

3-[2-[2-[2-[2-(tert-butoxycarbonylamino)ethoxy]ethoxy]ethoxy]ethoxy]propanoic acid (756525-91-4) + benzyl bromide (100-39-0) → C23H37NO8 (1351397-20-0)

Conditions	Yield
With potassium carbonate; sodium iodide In N,N-dimethyl-formamide at 20℃; Cooling with ice;	69%

3-[2-[2-[2-[2-(tert-butoxycarbonylamino)ethoxy]ethoxy]ethoxy]ethoxy]propanoic acid (756525-91-4) + N-(5-aminopentyl)-5-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazole-4-yl)pentanamide (115416-38-1) → C31H57N5O9S

Conditions	Yield
Stage #1: 3-[2-[2-[2-[2-(tert-butoxycarbonylamino)ethoxy]ethoxy]ethoxy]ethoxy]propanoic acid With 1-hydroxy-pyrrolidine-2,5-dione; dicyclohexyl-carbodiimide In dichloromethane at 0 - 20℃; for 2.16667h; Stage #2: N-(5-aminopentyl)-5-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazole-4-yl)pentanamide With triethylamine In N,N-dimethyl-formamide at 20℃;	65%

3-[2-[2-[2-[2-(tert-butoxycarbonylamino)ethoxy]ethoxy]ethoxy]ethoxy]propanoic acid (756525-91-4) + (2S,3S,4R)-3,4-bis-tert-butyldimethylsilyloxy-2-hexacosanoylamino-1-(2,3,4-tri-O-benzyl-6-hydroxy-α-D-galactopyranosyl)octadecane → (2S,3S,4R)-3,4-bis-tert-butyldimethylsilyloxy-2-hexacosanoylamino-1-(2,3,4-tri-O-benzyl-6-carbonyl-1-ethyl-2-(tri-1-ethanoyl)1-ethanoyl-2-(tert-butoxy-carbonyl)amino)-α-D-galactopyranosyloctadecane

Conditions

Yield

Stage #1: 3-[2-[2-[2-[2-(tert-butoxycarbonylamino)ethoxy]ethoxy]ethoxy]ethoxy]propanoic acid With O-(benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborate; N-ethyl-N,N-diisopropylamine In N,N-dimethyl-formamide at 20℃; for 0.5h; Stage #2: (2S,3S,4R)-3,4-bis-tert-butyldimethylsilyloxy-2-hexacosanoylamino-1-(2,3,4-tri-O-benzyl-6-hydroxy-α-D-galactopyranosyl)octadecane In N,N-dimethyl-formamide for 5h;

63%

3-[2-[2-[2-[2-(tert-butoxycarbonylamino)ethoxy]ethoxy]ethoxy]ethoxy]propanoic acid (756525-91-4) → tert-butyl (trans-4-{[2-({5-[(2S)-1-methylpyrrolidin-2-yl]pyridin-3-yl}oxy)ethyl]carbamoyl}cyclohexyl)carbamate (1351947-13-1) + tert-butyl [18-({5-[(2S)-1-methylpyrrolidine-2-yl]pyridine-3-yl}oxy)-15-oxo-3,6,9,12-tetraoxa-16-azaoctadeca-1-yl]carbamate (1351947-23-3)

Conditions	Yield
	A n/a B 56%

3-[2-[2-[2-[2-(tert-butoxycarbonylamino)ethoxy]ethoxy]ethoxy]ethoxy]propanoic acid (756525-91-4) + (S)-1-(5-chloro-6-(2H-1,2,3-triazol-2-yl)pyridin-3-yl)-3-(2-chloro-7-(1-(methylamino)ethyl)pyrazolo[1,5-a]pyrimidin-6-yl)urea hydrochloride → tert-butyl (S)-(17-(2-chloro-6-(3-(5-chloro-6-(2H-1,2,3-triazol-2-yl)pyridin-3-yl)ureido)pyrazolo[1,5-a]pyrimidin-7-yl)-16-methyl-15-oxo-3,6,9,12-tetraoxa-16-azaoctadecyl)carbamate

Conditions	Yield
With N-ethyl-N,N-diisopropylamine; HATU In N,N-dimethyl-formamide for 0.5h;	56%

3-[2-[2-[2-[2-(tert-butoxycarbonylamino)ethoxy]ethoxy]ethoxy]ethoxy]propanoic acid (756525-91-4) + 2-(2-((6-chlorohexyl)oxy)ethoxy)ethan-1-aminium 2,2,2-trifluoroacetate (744203-61-0) → C26H51ClN2O9

Conditions	Yield
With O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; N-ethyl-N,N-diisopropylamine In dichloromethane at 20℃; for 1h;	56%

3-[2-[2-[2-[2-(tert-butoxycarbonylamino)ethoxy]ethoxy]ethoxy]ethoxy]propanoic acid (756525-91-4) + 2-((5-chloro-2-((4-(piperazin-1-yl)phenyl)amino)pyrimidin-4-yl)amino)-N-methylbenzamide (1439934-41-4) → tert-butyl (15-(4-(4-((5-chloro-4-((2-(methylcarbamoyl)phenyl)amino)pyrimidin-2-yl)amino)phenyl)piperazin-1-yl)-15-oxo-3,6,9,12-tetraoxapentadecyl)carbamate

Conditions	Yield
With N-ethyl-N,N-diisopropylamine; HATU In N,N-dimethyl-formamide for 3h;	53.3%

3-[2-[2-[2-[2-(tert-butoxycarbonylamino)ethoxy]ethoxy]ethoxy]ethoxy]propanoic acid (756525-91-4) + p-nitrobenzenesulfonamide (6325-93-5) → C22H35N3O11S

Conditions	Yield
With dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In dichloromethane at 20℃; for 5h; Inert atmosphere;	53%

3-[2-[2-[2-[2-(tert-butoxycarbonylamino)ethoxy]ethoxy]ethoxy]ethoxy]propanoic acid (756525-91-4) + rac-2-piperidin-4-yl-1,2,4,10-tetrahydro-3-oxa-10-azaphenanthren-9-one trifluoroacetate (1520890-12-3) → rac-(2-{2-[2-(2-{3-oxo-3-[4-(9-oxo-1,4,9,10-tetrahydro-2H-3-oxa-10-azaphenanthren-2-yl)piperidin-1-yl]propoxy}ethoxy)ethoxy]ethoxy}ethyl)carbamic acid tert-butyl ester (1520890-16-7)

Conditions	Yield
With O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; N-ethyl-N,N-diisopropylamine In 1-methyl-pyrrolidin-2-one at 20℃; for 18h; Inert atmosphere;	52%

3-[2-[2-[2-[2-(tert-butoxycarbonylamino)ethoxy]ethoxy]ethoxy]ethoxy]propanoic acid (756525-91-4) + RGD-C2 (1012048-05-3) → C44H70N12O13 (1012050-70-2)

Conditions	Yield
Stage #1: 3-[2-[2-[2-[2-(tert-butoxycarbonylamino)ethoxy]ethoxy]ethoxy]ethoxy]propanoic acid With 1-hydroxy-pyrrolidine-2,5-dione; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In N,N-dimethyl-formamide at 20℃; for 1h; Stage #2: RGD-C2 With N-ethyl-N,N-diisopropylamine In N,N-dimethyl-formamide for 6h;	46%

3-[2-[2-[2-[2-(tert-butoxycarbonylamino)ethoxy]ethoxy]ethoxy]ethoxy]propanoic acid (756525-91-4) + (2S)-4-[[(2R,3R,4R,5S,6R)-3-acetamido-4,5-dihydroxy-6-(hydroxymethyl)tetrahydropyran-2-yl]amino]-2-(tertbutoxycarbonylamino)-4-oxobutanoic acid → 3-[2-[2-[2-[2-[[(2S)-4-[[(2R,3R,4R,5S,6R)]-3-acetamido-4,5-dihydroxy-6-(hydroxymethyl)tetrahydropyran-2-yl]amino-2-(tert-butoxycarbonylamino)-4-oxobutanoyl]amino]ethoxy]ethoxy]ethoxy]ethoxy]propanoic acid

Conditions

Yield

Stage #1: 3-[2-[2-[2-[2-(tert-butoxycarbonylamino)ethoxy]ethoxy]ethoxy]ethoxy]propanoic acid With hydrogenchloride In 1,4-dioxane at 20℃; for 1h; Stage #2: (2S)-4-[[(2R,3R,4R,5S,6R)-3-acetamido-4,5-dihydroxy-6-(hydroxymethyl)tetrahydropyran-2-yl]amino]-2-(tertbutoxycarbonylamino)-4-oxobutanoic acid With N-ethyl-N,N-diisopropylamine; N-[(dimethylamino)-3-oxo-1H-1,2,3-triazolo[4,5-b]pyridin-1-yl-methylene]-N-methylmethanaminium hexafluorophosphate In 1,4-dioxane; N,N-dimethyl-formamide at 20℃; for 0.51h;

43%

3-[2-[2-[2-[2-(tert-butoxycarbonylamino)ethoxy]ethoxy]ethoxy]ethoxy]propanoic acid (756525-91-4) + (E)-4-(4-(2-aminoethyl)piperazin-1-yl)-1-(4-(4-(4-phenoxyphenoxy)-5H-pyrrolo[3,2-d]pyrimidin-5-yl)piperidin-1-yl)but-2-en-1-one → tert-butyl (E)-(15-oxo-18-(4-(4-oxo-4-(4-(4-(4-phenoxyphenoxy)-5H-pyrrolo[3,2-d]pyrimidin-5-yl)piperidin-1-yl)but-2-en-1-yl)piperazin-1-yl)-3,6,9,12-tetraoxa-16-azaoctadecyl)carbamate

Conditions	Yield
With 2,4,6-tripropyl-1,3,5,2,4,6-trioxatriphosphinane-2,4,6-trioxide; triethylamine In dichloromethane; ethyl acetate at 20℃; for 6h;	33.4%

Upstream product

• 663921-15-1 3-[2-(2-{2-[2-(2-aminoethoxy)ethoxy]ethoxy}ethoxy)ethoxy]propanoic acid 
• 24424-99-5 di-tert-butyl dicarbonate 
• 106984-09-2 2-<2-<2-<2-<(tert-Butoxycarbonyl)amino>ethoxy>ethoxy>ethoxy>ethanol 

Downstream Products

• 663921-15-1 3-[2-(2-{2-[2-(2-aminoethoxy)ethoxy]ethoxy}ethoxy)ethoxy]propanoic acid 
• 1351397-20-0 C₂₃H₃₇NO₈ 
• 778648-12-7 2,5-dioxopyrrolidin-1-yl 2,2-dimethyl-4-oxo-3,8,11,14,17-pentaoxa-5-azaicosan-20-oate 

Relevant academic research and scientific papers

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