144292-53-5

Basic information

• Product Name: 1-(Benzyloxy)-2,3-difluorobenzene
• Synonyms: 1-(Benzyloxy)-2,3-difluorobenzene
• CAS NO: 144292-53-5
• Molecular Formula: C₁₃H₁₀F₂O
• Molecular Weight: 220.2147064
• Mol File: 144292-53-5.mol

Chemical Properties

• Boiling Point: 289.7±25.0 °C(Predicted)
• Appearance: /
• Density: 1.206±0.06 g/cm3(Predicted)
• CAS DataBase Reference: 1-(Benzyloxy)-2,3-difluorobenzene(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(Benzyloxy)-2,3-difluorobenzene(144292-53-5)
• EPA Substance Registry System: 1-(Benzyloxy)-2,3-difluorobenzene(144292-53-5)

Safety Data

• Hazardous Substances Data: 144292-53-5(Hazardous Substances Data)

Usage

Structure

A benzene ring with a benzyl ether group and two fluorine atoms attached at the 2 and 3 positions.

Organic synthesis

Used as a building block for creating various biologically active molecules.

Pharmaceutical research

Utilized in the development of new drugs and pharmaceutical compounds.

Agrochemicals

Serves as a starting material for the synthesis of agrochemicals.

Specialty chemicals

Acts as a precursor for the production of specialty chemicals.

Versatility

Wide range of applications in the field of organic chemistry.

Upstream product

• 6418-38-8 2,3-difluorophenol 
• 100-39-0 benzyl bromide 
• 1489-53-8 1,2,3-trifluorobenzene 
• 100-51-6 benzyl alcohol 
• 144292-32-0 2,3-difluoro-4-bromophenol 
• 100-44-7 benzyl chloride 
• 121219-16-7 (2,3-difluorophenyl)boronic acid 
• 367-11-3 ortho-difluorobenzene 

Downstream Products

• 175968-39-5 2,3-difluoro-4-hydroxybenzoic acid 
• 122265-94-5 4-(dodecyloxy)-2,3-difluorobenzoic acid 
• 122265-99-0 2,3-difluoro-4-(undecyloxy)benzoic acid 
• 122265-98-9 4-(decyloxy)-2,3-difluorobenzoic acid 

Relevant articles and documents

BIREFRINGENCE IMPROVING AGENT, FERROELECTRIC LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE USING THE AGENT, AND COMPOUND

A main object of the present invention is to provide a birefringence improving agent that can realize a satisfactory white display even in a liquid crystal display device in which a ferroelectric liquid crystal composition is used and which can reduce the

Regioselective preparation of 3-alkoxy-4,5-difluoroanilines by S NAr

A simple and scalable procedure to introduce alcohols selectively at the 3-position of 3,4,5-trifluoroaniline is described. The procedure uses powdered NaOH as base and catalytic 15-crown-5 in refluxing toluene with a Dean-Stark trap. A short exploration of other nucleophiles and fluoroaryl electrophiles is also described.

V-Shaped switching and interlayer interactions in ferroelectric liquid crystals

Linear electrooptic responses in ferroelectric liquid crystals can be achieved via thresholdless switching. The molecular parameters for the design of ferroelectric liquid crystals that may yield a thresholdless response have not been delineated so far. In this article we explore some of the chemical design features that may be utilised in controlling switching processes, and we develop property-structure correlations in order to achieve materials that exhibit thresholdless behaviour. The Royal Society of Chemistry.

The synthesis and mesomorphic properties of some novel antiferroelectric liquid crystals

Several esters have been synthesised that exhibit the antiferroelectric smectic C phase. The core structures, like virtually all antiferroelectric materials, are very similar to that of MHPOBC. Lateral fluoro substituents have been used to reduce melting points and to investigate their effect on mesomorphic properties, spontaneous polarisation and tilt angle. A new device format reported by Lagerwall requires antiferroelectric liquid crystals with a 45° tilt angle. Novel antiferroelectric materials were prepared with fluoro substituents in lateral positions and in a terminal chain to provide low melting points, high antiferroelectric phase stability, high spontaneous polarisation and tilt angles of up to 45°. The synthetic routes to the novel materials are discussed, and the transition temperatures, tilt angles and spontaneous polarisations are compared to those of known materials.

Liquid crystal compounds and compositions

Smetic C liquid crystal compounds, represented by the following formula (1) or (2) are disclosed. R1-O-A1-C≡C-A2-CO-(O)P-R2 (2)wherein R1and R2are C1-18 alkyl groups; A is a cyclic group, such as aubstituted or unsubstituted 1,4-phenylene group, X is direct bond, O or C#IDW#C; Y is -C#IDW#C- or -CH2CH2-; one of A1and A2is 1,4-phenylene group and the other is, 2,3-difluoro-1,4-phenylene group; and p is 0 or 1. These compounds can provide ferroelectric liquid crystal composition of low viscosity, and are useful as a component giving negative dielectric anisotropy and enlarging a temperature range showing smetic C phase.