14475-59-3

Basic information

• Product Name: S-4-broMobutyl ethanethioate
• Synonyms: S-4-broMobutyl ethanethioate;1-Butanethiol, 4-bromo-, acetate;Acetic acid, thio-,S-(4-bromobutyl) ester;Ethanethioic acid, S-(4-bromobutyl) ester;S-(4-Bromobutyl) thioacetate
• CAS NO: 14475-59-3
• Molecular Formula: C₆H₁₁BrOS
• Molecular Weight: 211.11994
• Mol File: 14475-59-3.mol

Chemical Properties

• Appearance: /
• Density: 1.388 g/mL at 25 °C
• Refractive Index: n20/D1.518
• Storage Temp.: ?20°C
• CAS DataBase Reference: S-4-broMobutyl ethanethioate(CAS DataBase Reference)
• NIST Chemistry Reference: S-4-broMobutyl ethanethioate(14475-59-3)
• EPA Substance Registry System: S-4-broMobutyl ethanethioate(14475-59-3)

Safety Data

• Statements: 22-36/37/38
• Safety Statements: 26-36/37/39
• WGK Germany: 3
• Hazardous Substances Data: 14475-59-3(Hazardous Substances Data)

Usage

Uses

Used in Electronics Industry:
S-4-Bromobutyl ethanethioate is used as a precursor for the formation of self-assembled monolayers on gold electrodes. Its application is crucial in modifying the work function of these electrodes, which can significantly impact the performance of electronic devices and sensors.
Used in Nanotechnology:
In the field of nanotechnology, S-4-Bromobutyl ethanethioate is utilized as a building block for creating well-ordered nanostructures. The formation of self-assembled monolayers on metal surfaces allows for the development of advanced materials with tailored properties, such as improved conductivity, enhanced sensitivity, or specific chemical reactivity.
Used in Surface Science:
S-4-Bromobutyl ethanethioate plays a vital role in surface science, where it is employed to study the interactions between organic molecules and metal surfaces. The formation of self-assembled monolayers provides insights into the fundamental processes governing molecular adsorption, desorption, and rearrangement on surfaces, which can be applied to develop new surface coatings, sensors, and catalysts.
Used in Chemical Synthesis:
As a versatile organic compound, S-4-Bromobutyl ethanethioate can be used as a synthetic intermediate in the preparation of various complex molecules and materials. Its unique structural features and reactivity make it a valuable component in the synthesis of pharmaceuticals, dyes, and other specialty chemicals.

Upstream product

• 110-01-0 thiophene 
• 506-96-7 Acetyl bromide 
• 110-52-1 1,4-dibromo-butane 
• 507-09-5 tiolacetic acid 
• 10387-40-3 potassium thioacetate 
• 5162-44-7 1-bromo-4-butene 

Downstream Products

• 93-08-3 methyl 2-naphthyl ketone 
• 98-86-2 acetophenone 
• 1234871-32-9 E-1-(4-((5'-(6-oxo-5-thiaheptylsulfanyl)-2,2'-bithiophene-5-sulfanyl)methyl)phenyl)-2-p-tolyldiazene 
• 1361953-85-6 ethyl 6-(acetylthio)-2-((diphenylmethylene)amino)hexanoate 

Relevant articles and documents

Structural control of the horizontal double fixation of oligothiophenes on gold

Quaterthiophenes bearing one (1) or two (2) alkanethiol chains attached at the internal β-position of the outermost thiophene ring through a sulfide linkage have been synthesized. Cyclic voltammetric analysis of their electrochemical behavior in solution suggests that electrooxidation of the doubly substituted oligomer 2 leads to electrodeposition of a poly(disulfide) on the anode surface. Monolayers of 1 or 2 on gold surfaces have been investigated and characterized by cyclic voltammetry, ellipsometry, contact angle measurement, and X-ray photoelectron spectroscopy. The results of these investigations indicate that introduction of two thiol groups in the structure leads to double fixation of the oligothiophene chain with the main axis of the conjugated system oriented parallel to the surface. The effects of single versus double fixation of the quaterthiophene chain on the electrochemical properties and stability of the corresponding monolayers are discussed.

[FeFe]-hydrogenase H-cluster mimics mediated by mixed (S, Se) and (S, Te) bridging moieties: Insight into molecular structures and electrochemical characteristics

Two synthetic models of the active site of [FeFe]-hydrogenase containing mixed (S, Se) and (S, Te) bridges have been synthesized and characterized. These complexes [Fe2(CO)6{μ-S(CH2)4E-μ)}] (E?=?Se (1), Te (2))

QUINOLYL-CONTAINING COMPOUND AND PHARMACEUTICAL COMPOSITION, AND USE THEREOF

Provided is a quinolyl-containing compound as shown in general formula (I) or (II) or a pharmaceutically acceptable salt, a solvate, an active metabolite, a polymorph, an isotopic label, or an isomer thereof, and further provided are a pharmaceutical composition comprising the compound and use of the compound and the pharmaceutical composition. The provided compound has a dual molecule function, can serve as multi -target inhibitors of novel tyrosine kinase/histone deacetylase, can simultaneously achieve the effect of two inhibitors, has excellent biological activity and pharmacokinetic properties, and has the application potential particularly in the field of treatment of tumors.

Switching the subcellular organelle targeting of atomically precise gold nanoclusters by modifying the capping ligand

Here, we have achieved the target switching fluorescence imaging and photodynamic activity of hydrosoluble AuNCs from lysosomes to mitochondria through ligand exchange. This work unveils the ligand-regulated subcellular distribution of AuNCs by which new

Halogenated-1-(4-mercaptobutyl)-3-methylimidazole ionic liquid, preparation method and application thereof

The invention discloses a halogenated-1-(4-mercaptobutyl)-3-methylimidazole ionic liquid, a preparation method and application thereof. According to the invention, N-methylimidazole, potassium thioacetate and 1, 4-dihalobutane are adopted as the raw materials, and three steps of reactions are carried out to synthesize the target product. The method has the advantages of short reaction cycle, mild reaction conditions of the steps, simple post-treatment process, good repeatability and stability, and is suitable for popularization and application. The ionic liquid prepared by the method provided by the invention can be applied to a micro-extraction system of ionic liquid to serve as an extractant or dispersant. The ionic liquid prepared by the method provided by the invention greatly improves the fluorescence sensitivity of detection in biomacromolecule fluorescence detection, also can be used as a fluorescence probe for pesticide residue detection, and has good analytical application value.

Halogenated-1-(4-sulfydryl butyl)-3-methylimidazole ionic liquid, and preparation method and application thereof

The invention discloses halogenated-1-(4-sulfydryl butyl)-3-methylimidazole ionic liquid, and a preparation method and application thereof. The ionic liquid has a structural formula shown as the formula I. According to the halogenated-1-(4-sulfydryl butyl)-3-methylimidazole ionic liquid, sulfydryl butyl is used as a substituent group; lone pair electrons of sulfydryl can generate p-Pi conjugation with large Pi bonds on an imidazole ring; the distance from the sulfydryl to the imidazole ring is proper through the butyl; the conditions of repulsion force increase when the distance is too small and sulfydryl coating when the distance is too great are avoided; the microenvironment effect of the ionic liquid is combined, so that the fluorescence property of the ionic liquid can reach the optimum. The ionic liquid can be applied to an ionic liquid microextraction system, is used as an extracting agent or a dispersing agent, and is suitable for being popularized and applied to an organic solvent-free microextraction technology. When the ionic liquid is used in weak fluorescence compound or biomacromolecule fluorescence detection, the detection fluorescence sensitivity can be greatly improved; the analysis and application values are high.

Synthesis of thiol-containing amino acids through alkylation of glycinate ketimine

A general synthetic route for the synthesis of thiol-containing amino acids through alkylation of glycinate ketimine followed by hydrolysis was developed in this work. The common problems associated with the instability of ketimines and thioesters were so

Preparation of ω-tetrahydropyran-2-ylsulfanylalkylmagnesium chlorides: Useful reagents for the synthesis of 1-(ω-mercaptoalkyl)-1,2- dihydrobuckminsterfullerenes (C60)

ω-Tetrahydropyran-2-ylsulfanylalkylmagnesium chlorides are prepared as Grignard reagents containing protected mercaptoalkyl chains, which are useful for the direct introduction of ω-mercaptoalkyl chains to electrophiles. In order to prove the usefulness of these reagents, they were reacted with buckminsterfullerene (C60) to give 1-(ω-mercaptoalkyl)-1,2- dihydrobuckminsterfullerenes after the deprotection of THP group with TFA.