149379-71-5

Basic information

• Product Name: 3-Pyridinecarbonitrile,2-methoxy-4-methyl-(9CI)
• Synonyms: 3-Pyridinecarbonitrile,2-methoxy-4-methyl-(9CI);2-methoxy-4-methylpyridine-3-carbonitrile;2-methoxy-4-methylnicotinonitrile
• CAS NO: 149379-71-5
• Molecular Formula: C8H8N2O
• Molecular Weight: 148.16192
• Product Categories: PYRIDINE
• Mol File: 149379-71-5.mol

Chemical Properties

• Boiling Point: 272.3±35.0 °C(Predicted)
• Appearance: /
• Density: 1.12±0.1 g/cm3(Predicted)
• Storage Temp.: 2-8°C
• PKA: 0.61±0.18(Predicted)
• CAS DataBase Reference: 3-Pyridinecarbonitrile,2-methoxy-4-methyl-(9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Pyridinecarbonitrile,2-methoxy-4-methyl-(9CI)(149379-71-5)
• EPA Substance Registry System: 3-Pyridinecarbonitrile,2-methoxy-4-methyl-(9CI)(149379-71-5)

Safety Data

• Hazardous Substances Data: 149379-71-5(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
3-Pyridinecarbonitrile, 2-methoxy-4-methyl-(9CI) is used as an intermediate in the synthesis of various pharmaceuticals for its ability to facilitate the creation of complex molecules that can be utilized in the development of new medicines.
Used in Agricultural Industry:
In the agricultural sector, 3-Pyridinecarbonitrile, 2-methoxy-4-methyl-(9CI) is used as a precursor in the production of certain pesticides, contributing to the development of effective crop protection agents.
Used in Food Industry:
3-Pyridinecarbonitrile, 2-methoxy-4-methyl-(9CI) is employed as a flavoring agent in the food industry, where its unique properties can be harnessed to enhance the taste and aroma of various food products.
Used in Chemical Industry:
3-Pyridinecarbonitrile,2-methoxy-4-methyl-(9CI) is used as a building block in the synthesis of dyes and paints, where its chemical properties allow for the creation of vibrant colors and durable coatings.
Used in Rubber and Adhesives Industry:
3-Pyridinecarbonitrile, 2-methoxy-4-methyl-(9CI) is utilized in the production of rubber products and adhesives, where it can improve the performance and durability of these materials.
Used in Textile Industry:
In the textile industry, 3-Pyridinecarbonitrile, 2-methoxy-4-methyl-(9CI) is used in the development of waterproofing agents for fabrics, enhancing the functionality and versatility of textile products.

Upstream product

• 123-73-9 trans-Crotonaldehyde 
• 109-77-3 malononitrile 
• 124-41-4 sodium methylate 
• 65169-38-2 2-chloro-4-methyl-3-pyridinecarbonitrile 
• 875-35-4 2,6-dichloro-4-methylnicotinonitrile 
• 93271-59-1 1,2-dihydro-2-oxo-4-methylpyridine-3-carbonitrile 
• 4637-24-5 N,N-dimethyl-formamide dimethyl acetal 
• 67-56-1 methanol 

Downstream Products

• 243469-67-2 4-(2-hydroxy-2-phenylethyl)-2-methoxypyridine-3-carbonitrile 
• 243469-62-7 3-hydroxymethyl-2-methoxy-4-methylpyridine 
• 243469-77-4 methyl 2-<3-<<<(1,1-dimethylthyl)dimethylsilyl>oxy>methyl>-2-methoxypyrid-4-yl>-2-<(phenoxy)thiocarbonyloxy>ethanoate 
• 243469-68-3 methanesulfonic acid 2-(3-cyano-2-methoxy-pyridin-4-yl)-1-phenyl-ethyl ester 

Relevant articles and documents

BACTERICIDE COMPOSITION AND METHOD OF CONTROLLING PLANT DISEASE

It is to provide a fungicidal composition having stable and high fungicidal effects against cultivated crops infected with plant diseases resulting from plant diseases. A fungicidal composition containing as active ingredients (a) a benzoylpyridine derivative represented by the formula (I) or its salt: (wherein X is a halogen atom, a nitro group, a substitutable hydrocarbon group, a substitutable alkoxy group, a substitutable aryloxy group, a substitutable cycloalkoxy group, a hydroxyl group, a substitutable alkylthio group, a cyano group, a carboxyl group which may be esterified or amidated, or a substitutable amino group, n is 1, 2, 3 or 4; R1 is a substitutable alkyl group, R2' is a substitutable alkyl group, a substitutable alkoxy group, a substitutable aryloxy group, a substitutable cycloalkoxy group or a hydroxyl group, p is 1, 2 or 3, and R2" is a substitutable alkoxy group or a hydroxyl group, provided that at least two of R2' and R2" may form a condensed ring containing an oxygen atom) and (b) at least one another fungicide.

Alkylazinylcarbonitriles as building blocks in heterocyclic synthesis: A route for the synthesis of 4-methyl-2-oxopyridines

The reaction of 1 with active methylene reagents afforded the enaminoamides 2 which readily cyclised to the pyridones 5. Compound 5 condensed with DMFDMA to afford the dimethylamino pyridones 8. These coupled with aryldiazonium chloride to give hydrazonoals 10. Compound 2 coupled with aromatic diazonium salts to yield the arylazopyridines 4.

Studies on the preparation of 3,4-disubstituted 2-methoxypyridines

The synthesis of 2-methoxy-4-methylpyridine-3-carbonitrile (3) and its conversion, by way of alkylation of the C(4) methyl group, into the pyridyl acetic acid ester 6 is described.

A Simple Synthesis of 2-Methoxypyridine-3-carbonitriles

The condensation of propanedinitrile with several enals or enones in a methanol-sodium methoxide system provides a one-step route to 2-methoxypyridine-3-carbonitriles.Together with these compounds substituted 2-aminobenzene-1,3-dicarbonitriles, were obtained as by-products.