150026-75-8Relevant articles and documents
An enantioselective formal synthesis of montelukast sodium
Bollikonda, Satyanarayana,Mohanarangam, Saravanan,Jinna, Rajender Reddy,Kandirelli, Venkata Kiran Kumar,Makthala, Laxman,Sen, Saikat,Chaplin, David A.,Lloyd, Richard C.,Mahoney, Thomas,Dahanukar, Vilas Hareshwar,Oruganti, Srinivas,Fox, Martin E.
, p. 3891 - 3901 (2015/06/02)
A formal synthesis of the antiasthma drug montelukast sodium is described, wherein the key chiral diol intermediate was accessed with greater convergence of the C-C bond-forming steps as compared to previous routes. Improved synthetic efficiency was achie
PREPARATION OF MONTELUKAST AND ITS SALTS
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Page/Page column 33-34, (2008/12/05)
There is provided a process for the preparation of montelukast of the Formula (I).
Unsaturated hydroxyalkylquinoline acids as leukotriene antagonists
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, (2008/06/13)
Compounds having the formula I: STR1 are leukotriene antagonists and inhibitors of leukotriene biosynthesis. These compounds are useful as anti-asthmatic, anti-allergic, anti-inflammatory, and cytoprotective agents. They are also useful in treating angina, cerebral spasm, glomerular nephritis, hepatitis, endotoxemia, uveitis, and allograft rejection.
Fluorinated hydroxyalkylquinoline acids as leukotriene antagonists
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, (2008/06/13)
Compounds having the formula I: STR1 are leukotriene antagonists and inhibitors of leukotriene biosynthesis. These compounds are useful as anti-asthmatic, anti-allergic, anti-inflammatory, and cytoprotective agents. They are also useful in treating angina, cerebral spasm, glomerular nephritis, hepatitis, endotoxemia, uveitis, and allograft rejection.