151358-47-3Relevant articles and documents
Convenient synthesis of bis(indol)alkanes by niobium(V) chloride
Heravi, Majid M.,Nahavandi, Fatemeh,Sadjadi, Samaheh,Oskooie, Hosien A.,Tajbakhsh, Mahmood
, p. 3285 - 3292 (2009)
Bis(indolyl)alkanes have been synthesized in excellent yields in the presence of a catalytic amount of niobium(V) chloride under solvent-free conditions. Copyright Taylor & Francis Group, LLC.
Micron particles of AlN/Al: Efficient, novel, and reusable heterogeneous catalyst for the synthesis of Bis(indolyl)methanes
Tekale, Sunil U.,Shisodia, Suresh S.,Kauthale, Sushma S.,Jadhav, Vivekanand B.,Kanhe, Nilesh S.,Bhoraskar, Sudha V.,Pawar, Rajendra P.
, p. 1849 - 1858 (2013)
The present work introduces for the first time the catalytic utility of micron particulate aluminium nitride (AlN/Al) as a novel and reusable heterogeneous catalyst for the synthesis of bis(indolyl)methanes involving the electrophilic substitution of indo
Boron trifluoride supported on nano-SiO2: An efficient and reusable heterogeneous catalyst for the synthesis of bis(indolyl)methanes and oxindole derivatives
Saffar-Teluri, Ali
, p. 1061 - 1067 (2014)
Boron trifluoride supported on nano-SiO2 was used as an efficient and heterogeneous catalyst for the electrophilic substitution reaction of indole with various aromatic aldehydes and isatins in methanol to afford the corresponding bis(indolyl)m
CuBr2-catalyzed synthesis of bis(indolyl)methanes
Mo, Li-Ping,Ma, Zi-Chuan,Zhang, Zhan-Hui
, p. 1997 - 2004 (2005)
Copper(II) bromide is found to be an efficient catalyst for the electrophilic substitution reaction of indole with aldehydes to afford the corresponding bis(indolyl)-methanes in good yields. Copyright Taylor & Francis, Inc. 1997-2004.
Ion Exchange Resin Catalyzed Condensation of Indole and Carbonyl Compounds - Synthesis of bis-Indolylmethanes
Feng, Xin-Liang,Guan, Chuan-Jin,Zhao, Cheng-Xue
, p. 487 - 492 (2004)
The condensation reactions of indole with some carbonyl compounds were found to be catalyzed effectively by ion exchange resins under mild conditions.
Enhanced catalytic activity of Zr(IV) complex with simple tetradentate Schiff base ligand in the clean synthesis of indole derivatives
Jafarpour, Maasoumeh,Rezaeifard, Abdolreza,Gorzin, Ghorbanali
, p. 1732 - 1736 (2011)
Zirconium (IV) tetradentate Schiff base (salphen) complex has been successfully used for efficient synthesis of wide variety of indole derivatives in EtOH as a standard green solvent under mild conditions. The investigation of turnover number and reusabil
Diindolylmethane Derivatives: Potent Agonists of the Immunostimulatory Orphan G Protein-Coupled Receptor GPR84
Pillaiyar, Thanigaimalai,K?se, Meryem,Sylvester, Katharina,Weighardt, Heike,Thimm, Dominik,Borges, Gleice,F?rster, Irmgard,Von Kügelgen, Ivar,Müller, Christa E.
, p. 3636 - 3655 (2017)
The Gi protein-coupled receptor GPR84, which is activated by (hydroxy)fatty acids, is highly expressed on immune cells. Recently, 3,3′-diindolylmethane was identified as a heterocyclic, nonlipid-like GPR84 agonist. We synthesized a broad range of diindolylmethane derivatives by condensation of indoles with formaldehyde in water under microwave irradiation. The products were evaluated at the human GPR84 in cAMP and β-arrestin assays. Structure-activity relationships (SARs) were steep. 3,3′-Diindolylmethanes bearing small lipophilic residues at the 5- and/or 7-position of the indole rings displayed the highest activity in cAMP assays, the most potent agonists being di(5-fluoro-1H-indole-3-yl)methane (38, PSB-15160, EC50 80.0 nM) and di(5,7-difluoro-1H-indole-3-yl)methane (57, PSB-16671, EC50 41.3 nM). In β-arrestin assays, SARs were different, indicating biased agonism. The new compounds were selective versus related fatty acid receptors and the arylhydrocarbon receptor. Selected compounds were further investigated and found to display an ago-allosteric mechanism of action and increased stability in comparison to the lead structure.
Facile synthesis of bis(indolyl)alkanes catalyzed by cu(clo 4)2.6h2o under solvent free conditions
Baruah, Mukulesh
, p. 461 - 463 (2011)
Copper perchlorate hexahydrate is found to be an efficient catalyst for the electrophilic substitution of indole with carbonyl compounds to prepare bis(indolyl)methane derivatives without solvent in excellent yield at room temperature.
A new catalytic method for ecofriendly synthesis of bis- and trisindolylmethanes by zirconyldodecylsulfate under mild conditions
Jafarpour, Maasoumeh,Rezaeifard, Abdolreza,Golshani, Tayebeh
, p. 535 - 539 (2009)
(Chemical Equation Presented) Zirconyldodecylsulfate (ZrO(DS)2) as a versatile Lewis acid-surfactant-combined (LASC) catalyzed ecofriendly synthesis of bis- and tris(indolyl)methanes via electrophilic substitution of indoles with carbonyl compo
An effective green and ecofriendly catalyst for synthesis of bis(indolyl)methanes as promising antimicrobial agents
Nemallapudi, Bakthavatchala Reddy,Zyryanov, Grigory V.,Avula, Balakrishna,Guda, Mallikarjuna Reddy,Gundala, Sravya
, p. 3324 - 3332 (2019)
An effective and suitable meglumine-catalyzed high-yielding process was considered and engaged for the synthesis of new bis(indolyl)methanes at ambient temperature under aqueous conditions. The catalytic reaction proceeds very smoothly. Clean reaction, ea
