155164-67-3Relevant articles and documents
2-Acylpyridazin-3-ones: Novel mild and chemoselective acylating agents for amines
Kang, Young-Jin,Chung, Hyun-A,Kim, Jeum-Jong,Yoon, Yong-Jin
, p. 733 - 738 (2007/10/03)
2-Acyl-4,5-dichloropyridazin-3-ones served as excellent novel N-acylating reagents for amines under neutral conditions in organic solvent. They are convenient, chemoselective and easy to handle stable N-acylating reagents of amines.
Fungicidal and genotoxic activity of new substituted pyridazinones
Carmellino,Massolini,Pagani,Zani,Leri
, p. 1427 - 1438 (2007/10/02)
Some 2-sulfonyl- and 2-acylderivatives of the 4,5-dichloro-3 (2H)- pyridazinone were prepared in order to test their fungicidal activity. Interesting results, both in vitro and in vivo, were obtained in particular from the alkylsulfonyl-derivatives. Genotoxic activity of 3(2H)-pyridazinones was evaluated in vitro by the Bacillus subtilis rec-assay and the Salmonella- microsome reversion assay.