15666-84-9Relevant articles and documents
Synthesis and structure of 2-pyransoylperimidines
Smellie, Iain A.S.,Fromm, Andreas,Moggach, Stephen A.,Paton, R. Michael
, p. 43 - 49 (2011)
The first examples of 2-pyranosylperimidines are reported. The β-d-glucopyranosyl nitrile oxide 5, generated by base-induced dehydrochlorination of the hydroximoyl chloride 4, reacted with 1,8-diaminonaphthalene to afford the 2-(β-d-glucopyranosyl)perimid
A new route to 2-substituted perimidines based on nitrile oxide chemistry
Smellie, Iain A.S.,Fromm, Andreas,Paton, R. Michael
, p. 4104 - 4106 (2009)
A new route to perimidines has been developed which involves reaction of a nitrile oxide with 1,8-diaminonaphthalene. Benzonitrile oxide, generated by dehydrochlorination of benzohydroximoyl chloride, and 1,8-diaminonaphthalene afforded 2-phenylperimidine
Unexpected Reaction Pathways in the Reaction of Alkoxyalkynyl-chromium(0) Carbenes with Aromatic Dinucleophiles
Sierra, Miguel A.,Mancheno, Maria J.,Del Amo, Juan C.,Fernandez, Israel,Gomez-Gallego, Mar
, p. 4943 - 4953 (2003)
Thermal- or SiO2-induced reactions of the Michael adducts of 1,2-aromatic dinucleophiles and alkynyl-chromium(0) carbene complexes, compounds 7-10, form different products in good yields depending on the nature of the aromatic dinucleophile used. Thus, 1,2-diaminobenzene derivatives 7 and 8 rearrange to pentacarbonylchromium(0) isocyanide complexes 11, 12, 14, and 15 in a process that occurs through bicyclic intermediates 24. Adducts 9 derived from o-aminophenol give 2,3-dihydro-1,5-benzoxazepine derivatives 17 by intramolecular 1,2-addition, followed by protonation at the chromium center and reductive elimination. In contrast, base-promoted addition of the phenolic hydroxy group in compound 9a affords 3-ethoxy-5-phenyl-5,6-dihydro-2H-1,6-benzoxazocin-2-one (18), together with the expected adduct 17a. Compound 18 is formed by a nucleophilic addition to a CO ligand in a preformed carbene complex. This is a new example of the rare attack of a nucleophile on a CO ligand in a Fischer carbene complex. Adducts 10 form seven-membered-ring carbene complexes 19 and 20 by intramolecular aminolysis. In contrast, reaction of alkynyl carbene complexes with 1,8-diaminonaphthalene under very mild conditions leads to 2-substituted perimidines 33 together with the corresponding ethoxymethylmetal carbene complex 32 through an unprecedented fragmentation process in a formal retro-Aumann reaction.
Design, synthesis and biological evaluation of novel perimidine o-quinone derivatives as non-intercalative topoisomerase II catalytic inhibitors
Zhou, Du-Chao,Lu, Yu-Ting,Mai, Yan-Wen,Zhang, Chen,Xia, Jie,Yao, Pei-Fen,Wang, Hong-Gen,Huang, Shi-Liang,Huang, Zhi-Shu
, (2019/08/06)
For the development of novel anticancer agents, we designed and synthesized a total of 37 perimidine o-quinone derivatives containing the o-quinone group at the A or B ring and different substituents (alkyl groups, aryl groups or heterocycles) at the C ri
A Cobalt Catalyst Permits the Direct Hydrogenative Synthesis of 1H-Perimidines from a Dinitroarene and an Aldehyde
Schwob, Tobias,Ade, Mirco,Kempe, Rhett
, p. 3013 - 3017 (2019/05/15)
A new sustainable catalytic reaction, the synthesis of 1H- perimidines from a dinitroarene and an aldehyde in the presence of H2, was achieved. An earth-abundant metal catalyst was developed to permit the efficient, highly chemoselective, and c
ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME
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Paragraph 0063-0066, (2016/10/09)
The present invention relates to a novel benzo carbazole compound having excellent light-emitting function, hole transport ability, and electric transport ability; and an organic electroluminescent device comprising the same in at least one organic materi
Formation of Hydro-1,3-diazines by the Reaction of Benzo[b]cyclohepta[e][1,4]oxazine with α,γ-Diamines
Sato, Ohki,Seshimo, Manabu,Tsunetsugu, Josuke
, p. 568 - 569 (2007/10/03)
Contrary to a report that the reaction of benzo[b]cyclohepta[e] [1,4]oxazine 1 with α,γ-diamine 2b produces 1,2,3,4-tetrahydrocyclohepta[b][1,4]diazepine 4, the product was found to be 2-phenyl-3,4,5,6-tetrahydropyrimidine 5b and is peculiar to the reaction of 1 with α,γ-diamines 2 as well as β-aminamide 7.
Synthesis of 2-aralkyl-1H-perimidines
Reddy, R. Rambhupal,Rao, C. V. Chalapathi
, p. 367 - 369 (2007/10/02)
2-Aralkyl-1H-perimidines 3a-g and 4 have been synthesised by the condensation of 2-methyl/phenyl-4-arylidene-2-oxazolin-5-ones (2a-h) with 1,8-diaminonapthalene (1) and also by the pyrolysis of arylacetic acids 5.The structures of these compounds (3a-g an
An improved one-pot method for the preparation of 2-substituted 1H-perimidines
Maquestiau,Berte,Mayence,Vanden Eynde
, p. 2171 - 2180 (2007/10/02)
2-Substituted 1H-perimidines are readily prepared, in high yields, by refluxing a mixture of sodium pyrosulfite, an aldehyde, and 1,8-diaminonapthalene in aqueous ethanol or N,N-dimethylformamide. The method is of wide applicability except from
