161117-67-5 Usage
Uses
Used in Pharmaceutical Industry:
2,2,5,7,8-PENTAMETHYLCHROMAN-6-SULFONAMIDE is used as a therapeutic agent for the treatment of various diseases and conditions associated with oxidative damage and inflammation. Its antioxidant properties help protect cells from oxidative stress, while its anti-inflammatory effects contribute to the reduction of inflammation in the body.
Used in Cardiovascular Disease Treatment:
In the field of cardiovascular medicine, 2,2,5,7,8-PENTAMETHYLCHROMAN-6-SULFONAMIDE is used as a protective agent against oxidative damage in the heart and blood vessels. Its antioxidant properties help prevent the formation of harmful free radicals, reducing the risk of cardiovascular diseases such as atherosclerosis, hypertension, and myocardial infarction.
Used in Neurodegenerative Disorders Treatment:
2,2,5,7,8-PENTAMETHYLCHROMAN-6-SULFONAMIDE is used as a neuroprotective agent in the treatment of neurodegenerative disorders such as Alzheimer's disease, Parkinson's disease, and multiple sclerosis. Its antioxidant and anti-inflammatory properties help protect neurons from oxidative stress and inflammation, slowing down the progression of these disorders.
Used in Skin Aging and Anti-Aging Products:
In the cosmetics and skincare industry, 2,2,5,7,8-PENTAMETHYLCHROMAN-6-SULFONAMIDE is used as an anti-aging ingredient in various products. Its antioxidant properties help combat the effects of free radicals on the skin, reducing the appearance of fine lines, wrinkles, and age spots. Additionally, its anti-inflammatory effects can help soothe and calm irritated or inflamed skin.
Used in Research and Development:
2,2,5,7,8-PENTAMETHYLCHROMAN-6-SULFONAMIDE is also used in research and development for the discovery of new therapeutic agents and pharmaceutical compounds. Its unique structure and properties make it a valuable tool for studying the mechanisms of oxidative stress and inflammation, as well as for the development of novel treatments for a wide range of health issues.
Check Digit Verification of cas no
The CAS Registry Mumber 161117-67-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,6,1,1,1 and 7 respectively; the second part has 2 digits, 6 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 161117-67:
(8*1)+(7*6)+(6*1)+(5*1)+(4*1)+(3*7)+(2*6)+(1*7)=105
105 % 10 = 5
So 161117-67-5 is a valid CAS Registry Number.
InChI:InChI=1/C14H21NO3S/c1-8-9(2)13(19(15,16)17)10(3)11-6-7-14(4,5)18-12(8)11/h6-7H2,1-5H3,(H2,15,16,17)
161117-67-5Relevant articles and documents
Strategies for the solid-phase diversification of poly-L-proline-type II peptide mimic scaffolds and peptide scaffolds through guanidinylation
Flemer, Stevenson,Wurthmann, Alexander,Mamai, Ahmed,Madalengoitia, Jose S.
, p. 7593 - 7602 (2008/12/22)
(Chemical Equation Presented) A strategy for the solid-phase diversification of PPII mimic scaffolds through guanidinylation is presented. The approach involves the synthesis N-Pmc-N′-alkyl thioureas as diversification reagents. Analogues of Fmoc-Orn(Mtt)-OH can be incorporated into a growing peptide chain on Wang resin. Side chain deprotection with 1% TFA/CH2Cl2 followed by EDCI-mediated reaction of N-Pmc-N′-alkyl thioureas with the side chain amine affords arginine analogues with modified guanidine head groups. The scope, limitations, and incidental chemistry are discussed.
Synthetic routes to N-Pmc-N′,N″-disubstituted guanidines via EDCI-mediated guanylation of amines with N-Pmc-N′-substituted thioureas
Flemer Jr., Stevenson,Madalengoitia, Jose S.
, p. 1848 - 1860 (2008/02/10)
An overview of the facile and high-yielding EDCI-mediated reaction of amines with N-Pmc-N′-alkyl thioureas to afford guanidines is presented, in which the general scope and limitations of the reaction are probed. It was found that the N-sulfonyl-N′-substi
Enantioselective total synthesis of (-)-dehydrobatzelladine C
Collins, Shawn K.,McDonald, Andrew I.,Overman, Larry E.,Rhee, Young Ho
, p. 1253 - 1255 (2007/10/03)
The oxidation of two tethered Biginelli adducts was examined as a potential key step in total syntheses of highly oxidized batzelladine and crambescidin alkaloids. Although angular hydroxyl substitution could not be introduced, dehydrogenation was readily accomplished. This latter conversion is a key step in the first total synthesis of dehydrobatzelladine C.
