16817-43-9

Basic information

• Product Name: 5-BROMO-2-CHLOROANISOLE
• Synonyms: 5-BROMO-2-CHLOROANISOLE;4-BROMO-1-CHLORO-2-METHOXYBENZENE;4-CHLORO-3-METHOXYBROMOBENZENE;5-Bromo-2-chloroanisol;2-Chloro-5-bromoanisole;Benzene, 4-broMo-1-chloro-2-Methoxy-;4-Bromo-1-chloro-2-methoxybenzene, 5-Bromo-2-chlorophenyl methyl ether;5-BroMo-2-chloroanisole, 97+%
• CAS NO: 16817-43-9
• Molecular Formula: C₇H₆BrClO
• Molecular Weight: 221.48
• Product Categories: Anisole;Anisoles, Alkyloxy Compounds & Phenylacetates;Bromine Compounds;Chlorine Compounds;Ethers;Organic Building Blocks;Oxygen Compounds
• Mol File: 16817-43-9.mol

Chemical Properties

• Melting Point: 27-28℃
• Boiling Point: 240-245 °C748 mm Hg(lit.)
• Flash Point: 26 °C
• Appearance: Clear colorless to pale yellow/Liquid or Low Melting Solid
• Density: 1.631 g/mL at 25 °C(lit.)
• Vapor Pressure: 0.0922mmHg at 25°C
• Refractive Index: n20/D 1.587(lit.)
• Storage Temp.: Sealed in dry,Room Temperature
• Water Solubility: Soluble in water.
• CAS DataBase Reference: 5-BROMO-2-CHLOROANISOLE(CAS DataBase Reference)
• NIST Chemistry Reference: 5-BROMO-2-CHLOROANISOLE(16817-43-9)
• EPA Substance Registry System: 5-BROMO-2-CHLOROANISOLE(16817-43-9)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36/37/39-24/25
• WGK Germany: 3
• Hazardous Substances Data: 16817-43-9(Hazardous Substances Data)

Usage

Uses

Used in Chemical Synthesis:
5-BROMO-2-CHLOROANISOLE is used as a chemical intermediate for the production of 4-chloro-3-methoxy-benzonitrile. This synthesis process takes place at a temperature of 110°C and requires the use of a solvent, specifically dimethylformamide, to facilitate the reaction.
In the Chemical Industry:
5-BROMO-2-CHLOROANISOLE serves as a valuable compound in the chemical industry due to its unique properties and reactivity. It can be utilized in the synthesis of various other organic compounds, contributing to the development of new materials and products.

InChI:InChI=1/C7H6BrClO/c1-10-7-4-5(8)2-3-6(7)9/h2-4H,1H3

Upstream product

• 18282-59-2 4-bromo-1,2-dichlorobenzene 
• 124-41-4 sodium methylate 
• 183802-98-4 5-bromo-2-chlorophenol 
• 77-78-1 dimethyl sulfate 
• 59557-91-4 4-bromo-2-methoxyaniline 
• 13726-14-2 4-chloro-m-anisidine 
• 71-43-2 benzene 
• 74-88-4 methyl iodide 

Downstream Products

• 189628-40-8 4-chloro-3-methoxybenzonitrile 
• 834895-50-0 4-chloro-3-methoxybenzophenone 
• 865305-29-9 1-chloro-4-cyclopropyl-2-methoxy-benzene 
• 1056167-65-7 2-(4-chloro-3-methoxy-phenyl)-1-oxo-2,8-diaza-spiro[4.5]decane-8-carboxylic acid tert-butyl ester 
• 174913-22-5 5-bromo-2,4-dichloroanisole 
• 13659-23-9 2-Bromo-5-chlorophenol 
• 142476-45-7 4-chloro-3-methoxyphenylethynyl-trimethylsilane 
• 61150-48-9 4-chloro-3-methoxybenzenethiol 
• 89694-47-3 (4-chloro-3-methoxyphenyl)boronic acid 
• 936092-35-2 2-chloro-N⁴-(4-chloro-3-methoxyphenyl)-5-methylpyrimidin-4-amine 
• 906071-12-3 1-(4-Chloro-3-methoxy-phenyl)-3,3,5,5-tetramethyl-[1,4]diazepane 
• 1018324-01-0 ethyl 1-(4-chloro-3-methoxyphenyl)piperidine-4-carboxylate 
• 1018325-68-2 8-(4-chloro-3-methoxyphenyl)-1,4-dioxa-8-azaspiro[4.5]decane 
• 1200449-29-1 C₁₃H₁₁ClO₃ 

Relevant articles and documents

BENZOXABOROLE COMPOUNDS AND FORMULATIONS THEREOF

A benzoxaborole formulation composition including a benzoxaborole, a non-ionic surfactant, or a non-ionic and ionic surfactant mixture, and a carrier is described herein. At least one of the non-ionic surfactant, the non-ionic and ionic surfactant mixture

Active Molybdenum-Based Anode for Dehydrogenative Coupling Reactions

A new and powerful active anode system that can be operated in 1,1,1,3,3,3-hexafluoro-2-propanol (HFIP) has been discovered. In HFIP the molybdenum anode forms a compact, conductive, and electroactive layer of higher-valent molybdenum species. This system can replace powerful but stoichiometrically required MoV reagents for the dehydrogenative coupling of aryls. This electrolytic reaction is more sustainable and allows the conversion of a broad scope of activated arenes.