169749-99-9

Basic information

• Product Name: (3S)-(+)-1-Benzyl-3-(methylamino)pyrrolidine
• Synonyms: (3S)-(+)-1-BENZYL-3-(METHYLAMINO)PYRROLIDINE;(S)-1-BENZYL-3-METHYLAMINOPYRROLIDINE;(S)-1-benzyl-N-methylpyrrolidin-3-amine;(S)-N-Benzyl-3-methylaminopyrrolidine;(S)-(1-Benzyl-pyrrolidin-3-yl)-methyl-amine;(3S)-1-benzyl-N-Methylpyrrolidin-3-aMine;(3S)-1-Benzyl-N-methyl-3-pyrrolidinamine;(3S)-(+)-1-Benzyl-3-(methylamino)pyrrolidine
• CAS NO: 169749-99-9
• Molecular Formula: C₁₂H₁₈N₂
• Molecular Weight: 190.28
• Product Categories: 3-Aminopyrrolidines;Amines (Chiral);Chiral 3-Aminopyrrolidines;Chiral Building Blocks;Synthetic Organic Chemistry
• Mol File: 169749-99-9.mol

Chemical Properties

• Boiling Point: 273.066 °C at 760 mmHg
• Flash Point: 105.62 °C
• Appearance: /
• Density: 0,99 g/cm3
• Vapor Pressure: 0.006mmHg at 25°C
• Refractive Index: 3 ° (C=10, EtOH)
• Storage Temp.: 2-8°C
• PKA: 10.16±0.20(Predicted)
• CAS DataBase Reference: (3S)-(+)-1-Benzyl-3-(methylamino)pyrrolidine(CAS DataBase Reference)
• NIST Chemistry Reference: (3S)-(+)-1-Benzyl-3-(methylamino)pyrrolidine(169749-99-9)
• EPA Substance Registry System: (3S)-(+)-1-Benzyl-3-(methylamino)pyrrolidine(169749-99-9)

Safety Data

• Hazard Codes: Xn
• Statements: 22-52
• RIDADR: 2735
• HazardClass: 8
• PackingGroup: III
• Hazardous Substances Data: 169749-99-9(Hazardous Substances Data)

Usage

Uses

Used in Organic Synthesis:
(3S)-(+)-1-Benzyl-3-(methylamino)pyrrolidine is utilized as a key intermediate in organic synthesis for the preparation of a variety of complex organic molecules. Its unique structure allows for the efficient construction of target compounds, enhancing the overall synthetic process.
Used in Medicinal Chemistry:
In the field of medicinal chemistry, (3S)-(+)-1-Benzyl-3-(methylamino)pyrrolidine is employed as a building block for the synthesis of pharmaceuticals. Its stereochemistry and structural features are crucial for the development of new drugs with improved efficacy and selectivity.
Used in Pharmaceutical Industry:
(3S)-(+)-1-Benzyl-3-(methylamino)pyrrolidine is used as a precursor in the pharmaceutical industry for the production of various drugs. Its unique properties enable the creation of molecules with specific therapeutic effects, contributing to the advancement of novel treatments for a range of diseases.
Used in Biologically Active Molecule Synthesis:
(3S)-(+)-1-Benzyl-3-(methylamino)pyrrolidine is also used as a component in the synthesis of biologically active molecules. Its incorporation into these molecules can lead to enhanced biological activity, making it a valuable tool in the development of new therapeutic agents.

InChI:InChI=1/C12H18N2/c1-13-12-7-8-14(10-12)9-11-5-3-2-4-6-11/h2-6,12-13H,7-10H2,1H3/t12-/m0/s1

Upstream product

• 131852-53-4 (S)-1-benzyl-3-(tert-butoxycarbonylamino)pyrrolidine 
• 116183-79-0 (3S)-3-<(4-tolylsulfonyl)oxy>-1-(phenylmethyl)pyrrolidine 
• 116143-02-3 (3R)-1-(phenylmethyl)pyrrolidin-3-ol Acetate 
• 101385-90-4 (R)-N-benzyl-3-hydroxypyrrolidine 
• 101385-90-4 (S)-N-benzyl-3-hydroxypyrrolidine 
• 116183-80-3 (3R)-3-<(4-tolylsulfonyl)oxy>-1-(phenylmethyl)pyrrolidine 
• 74-89-5 methylamine 

Downstream Products

• 169750-00-9 (S)-1-benzyl-3-[[N-(t-butoxycarbonyl)]-N-methylamino]pyrrolidine 
• 762286-16-8 ((S)-1-{[(S)-1-(4,4-Dimethyl-cyclohexyl)-pyrrolidin-3-yl]-methyl-carbamoyl}-pyrrolidin-3-yl)-methyl-carbamic acid tert-butyl ester 
• 848464-94-8 ((R)-1-{[(S)-1-(4,4-Dimethyl-cyclohexyl)-pyrrolidin-3-yl]-methyl-carbamoyl}-pyrrolidin-3-yl)-methyl-carbamic acid tert-butyl ester 
• 762286-17-9 (S)-3-Methylamino-pyrrolidine-1-carboxylic acid [(S)-1-(4,4-dimethyl-cyclohexyl)-pyrrolidin-3-yl]-methyl-amide 
• 762285-86-9 {(S)-1-[((S)-1-Benzyl-pyrrolidin-3-yl)-methyl-carbamoyl]-pyrrolidin-3-yl}-methyl-carbamic acid tert-butyl ester 
• 764722-59-0 ((R)-1-{(S)-3-[Methyl-(4'-trifluoromethyl-biphenyl-4-carbonyl)-amino]-pyrrolidine-1-carbonyl}-pyrrolidin-3-yl)-carbamic acid tert-butyl ester 

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