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Methyl 2-(4-hydroxyphenyl)benzoate, commonly known as methyl salicylate, is a versatile organic compound derived from the esterification of salicylic acid and methanol. It is characterized by its distinct wintergreen odor and possesses analgesic and anti-inflammatory properties, making it a valuable ingredient in various applications across the pharmaceutical, cosmetic, and food industries.

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  • 170304-68-4 Structure
  • Basic information

    1. Product Name: Methyl 2-(4-hydroxyphenyl)benzoate
    2. Synonyms: Methyl 2-(4-hydroxyphenyl)benzoate
    3. CAS NO:170304-68-4
    4. Molecular Formula: C14H12O3
    5. Molecular Weight: 228.24328
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 170304-68-4.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: 2-8°C
    8. Solubility: N/A
    9. CAS DataBase Reference: Methyl 2-(4-hydroxyphenyl)benzoate(CAS DataBase Reference)
    10. NIST Chemistry Reference: Methyl 2-(4-hydroxyphenyl)benzoate(170304-68-4)
    11. EPA Substance Registry System: Methyl 2-(4-hydroxyphenyl)benzoate(170304-68-4)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 170304-68-4(Hazardous Substances Data)

170304-68-4 Usage

Uses

Used in Pharmaceutical Industry:
Methyl 2-(4-hydroxyphenyl)benzoate is used as an analgesic and anti-inflammatory agent for its ability to alleviate pain and reduce inflammation. It is commonly found in topical pain relief products such as muscle rubs and joint creams, providing relief from muscle aches, joint pain, and inflammation.
Used in Cosmetic Industry:
In the cosmetic industry, methyl 2-(4-hydroxyphenyl)benzoate is used as a fragrance ingredient in personal care products due to its pleasant wintergreen scent. Its addition enhances the sensory experience of products such as perfumes, soaps, and lotions, making them more appealing to consumers.
Used in Food and Beverage Industry:
Methyl 2-(4-hydroxyphenyl)benzoate is used as a flavoring agent in the food and beverage industry. Its characteristic wintergreen flavor is utilized in the formulation of various food products, beverages, and confectionery items, adding a unique taste profile and enhancing the overall flavor experience.
Used in Aromatherapy:
Methyl 2-(4-hydroxyphenyl)benzoate is also used in aromatherapy for its potential therapeutic benefits. Its analgesic and anti-inflammatory properties may provide relief from muscle and joint pain when inhaled or applied topically. Additionally, its pleasant aroma can promote relaxation and stress relief.

Check Digit Verification of cas no

The CAS Registry Mumber 170304-68-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,7,0,3,0 and 4 respectively; the second part has 2 digits, 6 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 170304-68:
(8*1)+(7*7)+(6*0)+(5*3)+(4*0)+(3*4)+(2*6)+(1*8)=104
104 % 10 = 4
So 170304-68-4 is a valid CAS Registry Number.

170304-68-4Downstream Products

170304-68-4Relevant articles and documents

Synthesis of fluorenone and anthraquinone derivatives from aryl- and aroyl-substituted propiolates

Puenner, Florian,Schieven, Justin,Hilt, Gerhard

supporting information, p. 4888 - 4891 (2013/10/08)

Fluorenone derivatives were generated from aryl-substituted propiolates via a cobalt-catalyzed Diels-Alder reaction/DDQ-oxidation and Friedel-Crafts-type cyclization. Several functional groups are tolerated, and good to excellent overall yields (up to 89%) could be achieved. For the synthesis of anthraquinone derivatives, aroyl-substituted propiolates were applied in a zinc iodide catalyzed Diels-Alder reaction with 1,3-dienes. The subsequent DDQ oxidation and Friedel-Crafts-type cyclization led to symmetrical as well as some unsymmetrical anthraquinones in good to excellent yields of up to 87% over the three-step reaction sequence.

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