19246-18-5

Basic information

• Product Name: CYS-GLY
• Synonyms: L-CYSTEINYL GLYCINE;L-CYSTEINYLGLYCINE MONOHYDRATE;CYS-GLY;H-CYS-GLY-OH;cysteinylglycine;glycine,n-cysteinyl;n-l-cysteinyl-glycin;2-(2-amino-3-sulfanyl-propanoyl)aminoacetic acid
• CAS NO: 19246-18-5
• Molecular Formula: C₅H₁₀N₂O₃S
• Molecular Weight: 178.21
• Product Categories: Dipeptides;Dipeptides and Tripeptides;Peptides
• Mol File: 19246-18-5.mol

Chemical Properties

• Boiling Point: 459oC at 760 mmHg
• Flash Point: 231.4oC
• Appearance: /
• Density: 1.373g/cm3
• Vapor Pressure: 1.06E-09mmHg at 25°C
• Refractive Index: 1.557
• Storage Temp.: −20°C
• Solubility: DMSO (Slightly), Methanol (Slightly), Water (Slightly)
• PKA: 3.02±0.10(Predicted)
• Stability: Air Sensitive
• CAS DataBase Reference: CYS-GLY(CAS DataBase Reference)
• NIST Chemistry Reference: CYS-GLY(19246-18-5)
• EPA Substance Registry System: CYS-GLY(19246-18-5)

Safety Data

• Hazard Codes: Xn
• Statements: 22-36
• Safety Statements: 26
• WGK Germany: 3
• RTECS: MB9285800
• Hazardous Substances Data: 19246-18-5(Hazardous Substances Data)

Usage

Uses

Used in Chromatography:
CYS-GLY is used as a derivatization agent for p-hydroxymercury benzoate (PHMB) in the calibration of reversed phase chromatography. This application is particularly useful for coupling on-line and sequentially with a UV-visible diode array detector (RPLC-DAD), enhancing the accuracy and efficiency of the chromatographic process.
Used in Pharmaceutical Industry:
CYS-GLY, being a part of glutathione metabolism, has potential applications in the pharmaceutical industry. It can be utilized in the development of drugs targeting glutathione-related pathways, which may have implications for various therapeutic areas, including antioxidant defense, detoxification, and immune system regulation.
Used in Research and Development:
CYS-GLY can be employed as a research tool for studying the role of glutathione in cellular processes and its involvement in various diseases. This can lead to a better understanding of glutathione metabolism and the development of novel therapeutic strategies targeting this pathway.
Used in Analytical Chemistry:
CYS-GLY can be used as a reference compound or standard in analytical chemistry for the development and validation of new methods and techniques for the analysis of peptides and other related compounds. This can contribute to the advancement of analytical methodologies and the improvement of existing ones.

Biochem/physiol Actions

Cys-Gly is a precursor for glutathione biosynthesis in the neurons. It favors reactive oxygen species generation in the presence of transition metal ions. A normal level of cys-gly is essential for normal cellular function.

InChI:InChI=1/C5H10N2O3S/c6-3(2-11)5(10)7-1-4(8)9/h3,11H,1-2,6H2,(H,7,10)(H,8,9)/t3-/m0/s1

Upstream product

• 70-18-8 GLUTATHIONE 
• 74527-65-4 N-((R)-3-formyl-2,2-dimethyl-thiazolidine-4-carbonyl)-glycine 
• 2601-46-9 Z-L-Cys(Bzl)-Gly-OBzl 
• 166036-87-9 N-tert-butoxycarbonyl-S-(3,4-dimethylbenzyl)-L-cysteinylglycine 
• 7732-18-5 water 
• 2790-86-5 (Z-L-Cys-GlyOH)2 
• 7664-41-7 ammonia 
• 556-50-3 glycylglycine 
• 149227-97-4 N-((R)-3-formyl-2,2-dimethyl-thiazolidine-4-carbonyl)-glycine-methyl ester 

Downstream Products

• 4909-66-4 N-[N-(N-benzyloxycarbonyl-Ξ-γ-glutamyl)-L-cysteinyl]-glycine 
• 7729-20-6 L-cystinyl-bis-glycine 
• 127041-56-9 (6E,8E,10E)-(S)-5-Hydroxy-11-(1-methoxy-4-pentyl-cyclohexyl)-undeca-6,8,10-trienoic acid methyl ester 
• 91944-21-7 7Z,9E,11E,14Z-LTD₄ methyl ester 
• 7669-84-3 S-benzyl-L-cysteinylglycine 
• 79695-13-9 LTD5 
• 77165-74-3 Leukotrien D3 
• 73836-78-9 7Z,9E,11E,14Z-LTD₄ 
• 52-90-4 L-Cysteine 
• 56-40-6 glycine 
• 1349808-68-9 C₇₆H₉₈N₁₂O₁₈S₂ 

Related news

Binding of Hg2+ by Cys, CYS-GLY (cas 19246-18-5) and reduced glutathione: Study by differential pulse voltammetry on rotating Au-disk electrode, electrospray ionization mass-spectrometry and isothermal titration calorimetry08/03/2019

The study of Hg2+ binding with short-chain thiols as cysteine (Cys), dipeptide Cys-Gly and reduced glutathione (GSH) was performed by a recently proposed voltammetric method, using the rotating Au-disk electrode. For every thiol a similar complexation pattern was obtained. The highly stable Hg(t...detailed

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