23229-26-7

Basic information

• Product Name: 2,5-Dibromopyrazine
• Synonyms: 2,5-DIBROMOPYRAZINE;3,6-Dibromopyrazine, 2,5-Dibromo-1,4-diazine;2,5-Dibromopyrazine 95% (GC);2,5-bisbromopyrazine;PYRAZINE,2,5-DIBROMO
• CAS NO: 23229-26-7
• Molecular Formula: C₄H₂Br₂N₂
• Molecular Weight: 237.88
• EINECS: 1312995-182-4
• Product Categories: Halides;Pyrazines, Pyrimidines & Pyridazines;Building Blocks;Pyrazine
• Mol File: 23229-26-7.mol

Chemical Properties

• Melting Point: 45.0 to 49.0 °C
• Boiling Point: 234.044 °C at 760 mmHg
• Flash Point: 95℃
• Appearance: /
• Density: 2.197
• Vapor Pressure: 0.082mmHg at 25°C
• Refractive Index: 1.616
• Storage Temp.: 0-10°C
• PKA: -4.28±0.10(Predicted)
• CAS DataBase Reference: 2,5-Dibromopyrazine(CAS DataBase Reference)
• NIST Chemistry Reference: 2,5-Dibromopyrazine(23229-26-7)
• EPA Substance Registry System: 2,5-Dibromopyrazine(23229-26-7)

Safety Data

• Hazard Codes: Xi,Xn
• Statements: 22-36/37/38
• Safety Statements: 26-36/37/39
• WGK Germany: 3
• HazardClass: IRRITANT
• Hazardous Substances Data: 23229-26-7(Hazardous Substances Data)

Usage

Uses

Used in Chemical Industries:
2,5-Dibromopyrazine is used as a key intermediate in the synthesis of various organic compounds for chemical industries. Its unique reactivity and bromine substitutions make it suitable for conducting numerous organic reactions, such as amination, acylation, and urea bond formation.
Used in Research Laboratories:
In research laboratories, 2,5-Dibromopyrazine is utilized as a reagent for conducting various organic reactions and studying the properties of pyrazine compounds. Its stability and reactivity make it an ideal candidate for exploring new chemical reactions and developing novel synthetic pathways.
Used in Pharmaceutical Industry:
2,5-Dibromopyrazine can be used as a building block in the development of pharmaceutical compounds. Its unique structure and reactivity can be exploited to create new drug candidates with potential therapeutic applications.
Used in Agrochemical Industry:
In the agrochemical industry, 2,5-Dibromopyrazine can be employed as a precursor for the synthesis of various agrochemicals, such as pesticides and herbicides. Its reactivity and stability make it a valuable component in the development of effective and environmentally friendly agrochemicals.
Used in Dye and Pigment Industry:
2,5-Dibromopyrazine can be utilized in the dye and pigment industry for the synthesis of various dyes and pigments. Its unique structure and reactivity contribute to the development of new colorants with improved properties, such as enhanced color strength and stability.
Used in Material Science:
In material science, 2,5-Dibromopyrazine can be employed in the development of new materials with specific properties, such as conductivity, magnetism, or luminescence. Its unique structure and reactivity can be harnessed to create novel materials with potential applications in various fields, including electronics, sensors, and energy storage.

InChI:InChI=1/C4H2Br2N2/c5-3-1-7-4(6)2-8-3/h1-2H

Upstream product

• 59489-71-3 5-amino-2-bromopyrazine 
• 56423-63-3 2-bromopyrazine 
• 290-37-9 1,4-pyrazine 
• 1692-15-5 4-pyridylboronic acid 

Downstream Products

• 13051-89-3 dimethyl Pyrazine-2,5-dicarboxylate 
• 180049-21-2 2,5-Bis(2'-tert-butylcarbonylaminophenyl)pyrazine 
• 5398-63-0 2,5-diphenylpyrazine 
• 58861-90-8 2-methyl-5-phenylpyrazine 
• 329020-70-4 2,5-Bis(4'-tert-butoxycarbonylaminophenyl)pyrazine 
• 446286-90-4 2-bromo-5-(piperazin-1-yl)pyrazine 
• 55368-77-9 4,4'-(pyrazine-2,5-diyl)dibenzonitrile 
• 1049026-49-4 2-bromo-5-(methylsulfanyl)pyrazine 
• 1093418-77-9 2,5-diiodopyrazine 
• 1424016-69-2 (4-chlorophenyl)(3,6-dibromopyrazin-2-yl)methanone 
• 1424016-78-3 (4-(tert-butyl)phenyl)(3,6-dibromopyrazin-2-yl)methanone 
• 1428548-90-6 2,5-bis(p-tolylthio)pyrazine 
• 1562104-45-3 C₃₈H₃₈F₄N₄O₂ 
• 1613149-58-8 4-(5-bromopyrazin-2-yl)-N,N-diphenylaniline 

Relevant articles and documents

Structure property relationship of linear and angular pyrazine-based structural isomers with terminal D-A groups and evaluation of their photophysical properties

A series of pyrazine-based linear and angular shaped push-pull chromophores were synthesized by Sonogashira reaction and were further investigated by X-ray analysis. The photophysical properties were comprehensively studied both experimentally and through

The difference in the CO2adsorption capacities of different functionalized pillar-layered metal-organic frameworks (MOFs)

The excessive use of fossil energy has caused the CO2concentration in the atmosphere to increase year by year. MOFs are ideal CO2adsorbents that can be used in CO2capture due to their excellent characteristics. Studies of the structure-activity relationship between the small structural differences in MOFs and the CO2adsorption capacities are helpful for the development of efficient MOF-based CO2adsorbents. Therefore, a series of pillar-layered MOFs with similar structural and different functional groups were designed and synthesized. The CO2adsorption tests were carried out at 273 K to explore the relationship between the small structural differences in MOFs caused by different functional groups and the CO2adsorption capacities. Significantly, compound6which contains a pyridazinyl group has a 30.9% increase in CO2adsorption capacity compared to compound1with no functionalized group.

NOVEL COMPOUNDS AS GPR119 AGONISTS

The present invention relates to novel compounds of formula (I) as GPR119 agonist, composition compositions containing such compounds and method of preparation thereof.

RuII multinuclear metallosupramolecular rack-type architectures of polytopic hydrazone-based ligands: Synthesis, structural features, absorption spectra, redox behavior, and near-infrared luminescence

A novel class of polytopic hydrazone-based ligands was synthesized. They gave heteroleptic RuII polynuclear rack-like complexes of formula [Runterpyn molecular strand)]2n+ (terpy = 2,2′:6′,2″-terpyridine). The new rack-like systems can be viewed as being made of two identical or roughly identical peripheral subunits separated by several similar metal-containing spacer subunits. The presence of pyrazine or pyrimidine units within the molecular multitopic strands introduces additional chemical diversity; whereas a pyrimidine unit leads to appended orthogonal subunits that are on the same side with regard to the main molecular strand, a pyrazine unit leads to orthogonal subunits that lie on different sides. Mixing pyrazine and pyrimidine units within the same (bridging) molecular strand also allows peculiar and topographically controlled geometries to be obtained. Redox studies provided evidence that each species undergoes reversible redox processes at mild potentials, which can be assigned to specific subunits of the multicomponent arrays. Non-negligible electronic coupling takes place among the various subunits, and some electron derealization ex-tending over the overall bridging molecular strand takes place. In particular, oxidation data suggest that the systems can behave as p-type "molecular wires" and reduction data indicate that n-type electron conduction can occur within the multimetallic framework. All the multinuclear racks exhibit 3MLCT emission, both at 77 K in rigid matrix and at 298 K in fluid solution, which takes place in the near-infrared region (emission maxima in the 1000-1100 nm region), and is quite structured. Rigidity of the molecular structures and derealization within the large bridging ligands are proposed to contribute to the occurrence of the rather uncommon MLCT infrared emission, which is potentially interesting for optical communication devices.

BENZO ‘ D!AZEPINE DERIVATIVES FOR THE TREATMENT OF NEUROLOGICAL DISORDERS

The present invention relates to benzazepine derivatives of formula ( I ) wherein: R1 represents -C3-7 cycloalkyl optionally substituted by C1-3 alkyl; having pharmacological activity, processes for their preparation, to compositions containing them and to their use in the treatment of neurological and psychiatric disorders.