243469-59-2

Basic information

• Product Name: 2,5-Anhydro-1-azido-1-deoxy-D-glucitol
• Synonyms: 2,5-Anhydro-1-azido-1-deoxy-D-Glucitol
• CAS NO: 243469-59-2
• Molecular Formula: C₆H₁₁N₃O₄
• Molecular Weight: 189.17
• Product Categories: Sugars
• Mol File: 243469-59-2.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2,5-Anhydro-1-azido-1-deoxy-D-glucitol(CAS DataBase Reference)
• NIST Chemistry Reference: 2,5-Anhydro-1-azido-1-deoxy-D-glucitol(243469-59-2)
• EPA Substance Registry System: 2,5-Anhydro-1-azido-1-deoxy-D-glucitol(243469-59-2)

Safety Data

• Hazardous Substances Data: 243469-59-2(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
2,5-Anhydro-1-azido-1-deoxy-D-glucitol is used as a synthetic intermediate for the preparation of nucleotide sugar analogs, which are essential for the development of new drugs targeting various diseases.
Used in Drug Discovery:
2,5-Anhydro-1-azido-1-deoxy-D-glucitol is used as a key compound in drug discovery, providing a foundation for the development of novel therapeutic agents with potential antiviral and antifungal properties.
Used in Glycobiology Research:
2,5-Anhydro-1-azido-1-deoxy-D-glucitol is used as a valuable tool in glycobiology research, enabling the study of carbohydrate structures and their interactions with biological systems, which can lead to a better understanding of various biological processes and the development of new therapeutic strategies.
Used as a Prodrug Delivery System:
2,5-Anhydro-1-azido-1-deoxy-D-glucitol is used as a prodrug delivery system, offering a promising approach to improve the efficacy and targeting of therapeutic agents, particularly in the treatment of viral and fungal infections.

InChI:InChI=1/C6H11N3O4/c7-9-8-1-3-5(11)6(12)4(2-10)13-3/h3-6,10-12H,1-2H2/t3-,4+,5+,6+/m0/s1

Upstream product

• 243132-01-6 2,5-anhydro-1-azido-4,5-di-O-benzoyl-1-deoxy-D-glucitol 
• 65729-81-9 2,5-anhydro-1,3-O-isopropylidene-D-glucitol 
• 75499-83-1 2,5-anhydro-4,5-di-O-benzoyl-D-glucitol 
• 75499-82-0 2,5-anhydro-4,5-di-O-benzoyl-1,3-O-isopropylidene-D-glucitol 
• 27826-73-9 2,5-anhydro-D-glucitol 
• 1309924-06-8 2,5-anhydro-1-bromo-1-deoxy-D-glucitol 
• 157363-84-3 1,2:5,6-dianhydro-3,4-di-O-benzyl-L-iditol 
• 102093-93-6 2,5-anhydro-3,4-di-O-benzyl-1-bromo-1-deoxy-D-glucitol 
• 36199-02-7 3,4-di-O-benzyl-D-mannitol 
• 82064-07-1 2,5-anhydro-4,5-di-O-benzoyl-1-O-p-tolylsulfonyl-D-glucitol 

Downstream Products

• 1309855-93-3 1-(3,4,6-tri-O-acetyl-2,5-anhydro-1-deoxy-D-glucitolyl)-4-(4-N,N-dimethylaminophenyl)-[1,2,3]-triazole 
• 1309855-95-5 1-(3,4,6-tri-O-acetyl-2,5-anhydro-1-deoxy-D-glucitolyl)-4-(4-methoxyphenyl)-[1,2,3]-triazole 
• 1309855-98-8 1-(3,4,6-tri-O-acetyl-2,5-anhydro-1-deoxy-D-glucitolyl)-4-(1-hydroxy-1-phenylmethyl)-[1,2,3]-triazole 
• 1309855-99-9 1-(3,4,6-tri-O-acetyl-2,5-anhydro-1-deoxy-D-glucitolyl)-4-(1-hydroxycyclohexyl)-[1,2,3]-triazole 
• 1309856-04-9 1-(3,4,6-tri-O-acetyl-2,5-anhydro-1-deoxy-D-glucitolyl)-4-(4-aminophenyl)-[1,2,3]-triazole 
• 1309856-08-3 1-(3,4,6-tri-O-acetyl-2,5-anhydro-1-deoxy-D-glucitolyl)-4-(4-hydroxymethylphenyl)-[1,2,3]-triazole 
• 1309856-11-8 1-(2,5-anhydro-1-deoxy-D-glucitolyl)-4-(4-N,N-dimethylaminophenyl)-[1,2,3]-triazole 
• 1309856-13-0 1-(2,5-anhydro-1-deoxy-D-glucitolyl)-4-(4-methoxyphenyl)-[1,2,3]-triazole 
• 1309856-17-4 1-(2,5-anhydro-1-deoxy-D-glucitolyl)-4-(1-hydroxy-1-phenylmethyl)-[1,2,3]-triazole 
• 1309856-18-5 1-(2,5-anhydro-1-deoxy-D-glucitolyl)-4-(1-hydroxycyclohexyl)-[1,2,3]-triazole 
• 1309856-23-2 1-(2,5-anhydro-1-deoxy-D-glucitolyl)-4-(4-aminophenyl)-[1,2,3]-triazole 
• 1309856-24-3 1-(2,5-anhydro-1-deoxy-6-sulfo-D-glucitolyl)-4-(4-N,N-dimethylaminophenyl)-[1,2,3]-triazole 
• 1309856-26-5 1-(2,5-anhydro-1-deoxy-6-sulfo-D-glucitolyl)-4-(4-methoxyphenyl)-[1,2,3]-triazole 
• 1309856-30-1 1-(2,5-anhydro-1-deoxy-6-sulfo-D-glucitolyl)-4-(1-hydroxycyclohexyl)-[1,2,3]-triazole 

Relevant articles and documents

An efficient approach to 2,5-anhydro-glucitol-based 1′-homo-N- nucleoside mimetics

This Letter describes an efficient synthesis of a range of 1′-homo-N-nucleoside mimetics with a series of 4-substituted 1,2,3-triazoles replacing the natural nucleobase. The synthesis of 6-O-monosulfated 1′-homo-N-nucleoside mimetic derivatives is also discussed.

Ethambutol-sugar hybrids as potential inhibitors of mycobacterial cell-wall biosynthesis

Ethambutol is an established front-line agent for the treatment of tuberculosis, and is also active against Mycobacterium avium infection. However, this agent exhibits toxicity, and is considered to have low potency. The action of ethambutol on the mycoba